Genetic Counseling Practice in Next Generation Sequencing Research: Implications for the Ethical Oversight of the Informed Consent Process

The potential for next generation sequencing research (NGS) to generate individual genetic results could have implications for the informed consent process and the provision of genetic counseling. We undertook a content analysis of informed consent templates and guidelines produced by Canadian institutional review boards, purposively sampling documents used by researchers to obtain consent from participants in genetics studies. Our goal was to examine the extent to which the informed consent documents addressed genetic counseling and the return of individual genetic results. Our analysis reveals that the majority of informed consent documents did not mention genetic counseling while several did not mention the return of results. We found differences in the ways in which documents addressed availability of counseling, eligibility criteria for referral to a genetic counselor, genetic counselor involvement, provision of services to family members of participants and incidental findings. From an ethical standpoint, consent documents should provide appropriate information so that participants may make an informed decision about their participation in research. The need to ensure adequate counseling for study populations in an NGS research context will necessarily involve adapting values that underlie care in genetic counseling practice. If the interests of research participants are to be truly promoted, the drafting and review of informed consent documents should give proper due to genetic counseling.     

La qualité de vie au travail dans les services de ressources humaines

This research looks at work well-being for human resources staffs, which are brought to manage relations between individuals and organization, between organization and society, between individuals and society. 263 human resources staffs performed a questionnaire estimating work facets such professionals satisfaction and commitment, work conditions and health. Results shown firstly a work quality of life for staffs, what does not prevent them from reporting hardness (temporal constraints, working overload), secondly the absence of systematic effects of status, age and gender on work attitudes and health. Results and futur works are discussed.     

Transitions to Adulthood Among First Generation Sub-Saharan African Immigrant Adolescents in Canada: Evidence from a Qualitative Study in Montreal

In industrialized societies, a large number of studies have addressed the various patterns of adolescent transitions to adulthood. While most studies on migration have examined aspects of migrants’ integration into host societies, few researches, however, have dealt with the intersection of these two topics—the experiences and problems encountered by immigrant adolescents. This research focuses on the transition to adulthood among sub-Saharan African youth who live in Montreal, Canada. This group is still poorly known in Canada, and the few studies that exist on sub-Saharan Africans in Canada showed that they are among the most discriminated groups socially and economically. Both immigrant youth and their parents/families’ experience a transition to adapt to a new place, and these respective experiences may affect their relationships. Our research objectives are to examine the conditions in which African immigrant adolescents experience their transition to adulthood and to assess whether the gaps between the two perspectives are purely generational or are partly specific to this group. The data are based on qualitative focus group discussions and individual interviews conducted in Montreal in 2005–2007 among first generation immigrants from sub-Saharan Africa and a control group of native Canadians (whose parents were also born in Canada), men and women between age 12 and 18 and young adults aged 18 to 29. Our results show that in all cases the question of becoming responsible, making one’s own decision is central. What varies is the process through which the young people become responsible.     

Organizational Impression Management: Utilizing Anticipatory Tactics

The current pair of studies are the first to empirically show that the proposed tactics/processes (i.e., accommodation, legitimation, intimidation, bureaucratic) of the anticipatory organizational impression management (OIM) model decrease initial challenges to an event and prevent the escalation of an already existing challenge. Moreover, our data showed that variables specified by the model mediated the relationship between the tactics and the respective dependent measures (i.e., initial challenges, escalation of challenges). Our results offer compelling evidence for the OIM model, an empirical case that has been heretofore absent from the literature.     

Who are you looking at? The influence of face gender on visual attention and memory for own- and other-race faces

Previous research suggests that the own-race bias (ORB) in memory for faces is a result of other-race faces receiving less visual attention at encoding. As women typically display an own-gender bias in memory for faces and men do not, we investigated whether face gender and sex of viewer influenced visual attention and memory for own- and other-race faces, and if preferential viewing of own-race faces contributed to the ORB in memory. Participants viewed pairs of female or male own- and other-race faces while their viewing time was recorded. Afterwards, they completed a surprise memory test. We found that (1) other-race males received the initial focus of attention, (2) own-race faces were viewed longer than other-race faces over time, although the difference was larger for female faces, and (3) even though longer viewing time increased the probability of remembering a face, it did not explain the magnified ORB in memory for female faces. Importantly, these findings highlight that face gender moderates attentional responses to and memory for own- and other-race faces.     

Acquired affective associations induce emotion effects in word recognition: An ERP study

The present study examined how contextual learning and in particular emotionality conditioning impacts the neural processing of words, as possible key factors for the acquisition of words’ emotional connotation. 21 participants learned on five consecutive days associations between meaningless pseudowords and unpleasant or neutral pictures using an evaluative conditioning paradigm. Subsequently, event-related potentials were recorded while participants implicitly processed the learned emotional relevance in a lexical decision paradigm. Emotional and neutral words were presented together with the conditioned pseudowords and a set of new pseudowords. Conditioned and new pseudowords differed in the late positive complex. Emotionally and neutrally conditioned stimuli differed in an early time window (80–120 ms) and in the P300. These results replicate ERP effects known from emotion word recognition and indicate that contextual learning and in particular evaluative conditioning is suitable to establish emotional associations in words, and to explain early ERP effects in emotion word recognition.     

Metamemory beliefs and episodic memory in obstructive sleep apnea syndrome

This study assessed metamemory and its role in actual episodic memory performance in 26 patients with obstructive sleep apnea syndrome and 27 healthy controls. Metamemory knowledge and memory beliefs were assessed using the Metamemory Inventory in Adulthood. Episodic memory performance was investigated with the Remember/Know paradigm. Subjective sleepiness was evaluated. Patients underwent a polysomnographic assessment. In contrast to the control group's more stable memory beliefs, patients self-assessed their memory as declining across time, and felt more anxious about their memory. There was only a modest difference between patients' self-perceptions of their memory capacities and those of the control group, but patients' actual memory performance was strongly disturbed. While the latter was significantly correlated with severity of obstructive sleep apnea, scores on the Metamemory Inventory in Adulthood scales were not correlated with physiological measures, subjective sleepiness, or episodic memory performance. Obstructive sleep apnea may affect prefrontal cortex functioning and hence the ability to assess one's own memory impairment.     

Featural selective attention,exemplar representation,and the inverse base-rate effect

Selective attention plays a central role in theories of category learning and representation. In exemplar theory, selective attention has typically been formalized as operating uniformly across entire stimulus dimensions. Selective featural attention operating within dimensions has been recognized as a conceptual possibility, but relatively little research has focused on evaluating it. In the present research, we explored the usefulness of selective featural attention in the context of exemplar representation. We report the results of embedding the feature-to-category relations typically associated with the inverse base-rate effect—a classic and paradoxical category-learning result— perceptual category-learning task using a category structure with three multivalued feature dimensions. An exemplar model incorporating featural selective attention accurately accounted for the inverse base-rate effect that occurred but failed to do so with only dimensional attention.