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171.
Effects of antisocial personality, cocaine and opioid dependence, and gender on eye movement control
Substance-dependent patients have been reported to exhibit abnormal smooth pursuit and saccadic eye movements. However, contrasts of the effects of different substances and the effects of comorbid psychiatric symptoms such as antisocial personality have rarely been performed. Separate analyses examined the effects of cocaine dependence, opioid dependence, or antisocial personality disorder. In each analysis, sex was included as an additional grouping factor. The dependent measures were the gain of smooth pursuit eye movement and the delay and accuracy of saccadic eye movement. Analyses of covariance indicated that both cocaine dependence and antisocial personality, but not opiate dependence, were associated with a significant reduction in gain of smooth pursuit eye movement. Cocaine dependence and antisocial personality also slowed the onset of saccadic eye movements, but only in men. No group differences were found in the accuracy of saccadic eye movements. The results suggest that the neurophysiological effects of cocaine dependence and antisocial personality overshadow the effects of heroin. The significance of these findings for visual attention and reading skill has yet to be assessed. 相似文献
172.
Bratcher NA Farmer-Dougan V Dougan JD Heidenreich BA Garris PA 《Journal of the experimental analysis of behavior》2005,84(3):371-399
Dose-dependent changes in sensitivity to reinforcement were found when rats were treated with low, moderate, and high doses of the partial dopamine D1-type receptor agonist SKF38393 and with the nonselective dopamine agonist apomorphine, but did not change when rats were treated with similar doses of the selective dopamine D2-type receptor agonist quinpirole. Estimates of bias did not differ significantly across exposure to SKF38393 or quinpirole, but did change significantly at the high dose of apomorphine. Estimates of goodness of fit (r2) did not change significantly during quinpirole exposure. Poor goodness of fit was obtained for the high doses of SKF38393 and apomorphine. Decrements in absolute rates of responding were observed at the high dose of quinpirole and at the moderate and high doses of SKF38393 and apomorphine. Changes in r2 and absolute responding may be due to increases in stereotyped behavior during SKF38393 and apomorphine exposure that, in contrast to quinpirole, were distant from the response lever. The present data provide evidence that sensitivity to reward is affected more strongly by dopamine D1-like receptors rather than D2-like receptors, consistent with evidence from other studies investigating consummatory dopamine behavior and the tonic/phasic dopamine hypothesis. 相似文献
173.
Wingate LR Bobadilla L Burns AB Cukrowicz KC Hernandez A Ketterman RL Minnix J Petty S Richey JA Sachs-Ericsson N Stanley S Williams FM Joiner TE 《Suicide & life-threatening behavior》2005,35(6):615-629
The rise in suicide by African Americans in the United States is directly attributable to the dramatic, nearly three-fold increase in suicide rates of African American males. Gibbs (1997) hypothesized high social support, religiosity, and southern residence are protective factors against suicidality for Black people. This hypothesis was tested among 5,125 participants from the National Comorbidity Survey; 299 were African American males. In this study we hypothesized that there would be significantly lower suicidality in the South, and social support and religiosity would mediate this relationship. Our results indicate that Southern region is indeed a significant predictor of suicidal symptoms in African American men, such that suicidal symptoms were lower in the South, but religiosity and social support did not account for this effect. Other potential mediators were also examined. 相似文献
174.
This study examined the cross-sectional factorial invariance of anxiety sensitivity in an ethnically diverse sample of adolescents (n = 173; mean age 15.5 years) and young adults (n = 291; mean age 20.1 years). Research in adult and youth samples suggests that anxiety sensitivity is best understood as a hierarchical construct with several lower-order factors. Factor models based on previous research using both adult and youth samples were compared and a hierarchical model with three lower-order factors provided the best fit to the data. Results supported the hypothesis that the factor structure of the Anxiety Sensitivity Index was invariant across age and gender. The factor scores also demonstrated differential correlations with symptoms of anxiety and depression. Results are discussed with regard to construct validation and understanding the structure of anxiety sensitivity in youth. 相似文献
175.
176.
The authors tested whether older adults have greater difficulty than younger adults in ignoring task-irrelevant information during reading as a result of age-related decline in inhibitory processes. Participants were shown target sentences containing distractor words. They were instructed to read aloud each sentence and ignore distractors. The N400 event-related potential (ERP) was used to measure the extent of semantic processing of target and distracting information. It showed that younger adults semantically processed both target and distracting material, whereas online processing of target sentences in older adults was disrupted by the distractors. In older adults, memory for target information related to their susceptibility to distraction and inhibition efficiency. Implications for age-differences in inhibitory control, working memory, and resource capacity are discussed. 相似文献
177.
178.
Robert E. Warren Natalie Terbovic Warren John P. Green Jan H. Bresnick 《Memory & cognition》1978,6(4):364-371
The resolution of lexical ambiguity was studied in two experiments. While subsequent selection would appear to limit longer term storage to one meaning of an ambiguous word, multiple initial encoding of homophones and homographs was indicated by the intrusion of their alternative meanings across trials in a Brown-Peterson paradigm. In Experiment 1 subjects heard four words and then engaged in a 10osec distractor task. Written recall was then demanded. On context trials a homophone with two distinct alternative meanings was presented with other words biasing either a dominant or subordinate meaning, for example, look, stare,peer, glance. On the next trial words related to an alternative meaning were presented, for example, dock, wharf, quay, jetty. Intrusions of the graphic forms of alternative meanings le.g.,PIER) into critical trial recall occurred whether the dominant or subordinate meaning of the homophone had been biased by context. Experiment 2 employed visual presentation of homographs, for example, GOLD, IRON,LEAD, and oral recall, but was logically similar to Experiment 1. Intrusions of the alternative codings of homographs across trials again occurred, for example, GUIDE, DIRECT,lead, regardless of the meaning originally biased by context. 相似文献
179.
Jernigan Christopher M. Stafstrom Jay A. Zaba Natalie C. Vogt Caleb C. Sheehan Michael J. 《Animal cognition》2023,26(2):589-598
Animal Cognition - Visual individual recognition requires animals to distinguish among conspecifics based on appearance. Though visual individual recognition has been reported in a range of taxa... 相似文献
180.