Psychological stress in childhood and susceptibility to the chronic diseases of aging: moving toward a model of behavioral and biological mechanisms

Among people exposed to major psychological stressors in early life, there are elevated rates of morbidity and mortality from chronic diseases of aging. The most compelling data come from studies of children raised in poverty or maltreated by their parents, who show heightened vulnerability to vascular disease, autoimmune disorders, and premature mortality. These findings raise challenging theoretical questions. How does childhood stress get under the skin, at the molecular level, to affect risk for later diseases? And how does it incubate there, giving rise to diseases several decades later? Here we present a biological embedding model, which attempts to address these questions by synthesizing knowledge across several behavioral and biomedical literatures. This model maintains that childhood stress gets "programmed" into macrophages through epigenetic markings, posttranslational modifications, and tissue remodeling. As a consequence these cells are endowed with proinflammatory tendencies, manifest in exaggerated cytokine responses to challenge and decreased sensitivity to inhibitory hormonal signals. The model goes on to propose that over the life course, these proinflammatory tendencies are exacerbated by behavioral proclivities and hormonal dysregulation, themselves the products of exposure to early stress. Behaviorally, the model posits that childhood stress gives rise to excessive threat vigilance, mistrust of others, poor social relationships, impaired self-regulation, and unhealthy lifestyle choices. Hormonally, early stress confers altered patterns of endocrine and autonomic discharge. This milieu amplifies the proinflammatory environment already instantiated by macrophages. Acting in concert with other exposures and genetic liabilities, the resulting inflammation drives forward pathogenic mechanisms that ultimately foster chronic disease.     

The not‐sure response option in sequential lineup practice

Field implementation of double‐blind sequential lineups has prompted a question about the impact on eyewitness decisions of an explicit not‐sure response option. In this laboratory study, a video crime was viewed by 378 participants who then attempted to identify the culprit from a six‐person sequential or simultaneous‐format lineup that either included or did not include the culprit. Witnesses were provided either dichotomous forced‐choice (FC) response categories (yes/no) or a not‐sure option as one of three response categories (yes/no/not‐sure). The not‐sure option (NSO) significantly decreased witness choosing compared to the FC condition but only for sequential lineups. Both correct identifications and false alarms decreased. Diagnosticity was greatest for a sequential lineup with a NSO. The results suggest a criterion decision shift for witnesses who view a sequential lineup with a not‐sure response option. Copyright © 2010 John Wiley & Sons, Ltd.     

Nonsuicidal self‐injury across cultures and ethnic and racial minorities: A review

The field of nonsuicidal self‐injury (NSSI) is dominated by research conducted with Caucasian‐majority samples in Western countries such as United States, Canada, Australia and European countries. This article critically reviewed the empirical research on NSSI in non‐Western countries and among ethnic/racial minority individuals who live in the West to give voice to and understand the patterns of NSSI among individuals who do not fall within the dominant Caucasian majority. The study found both similarities and differences between Western and non‐Western data in terms of characteristics and functions of NSSI. Differences in gender patterns in regards to prevalence of NSSI and methods used as well as presence of a more relational functionality of NSSI rather than emotion regulation functionality were two points of divergence in the findings of these studies. In addition, the findings seem to indicate that the role of ethnicity/race is mediated by important factors such as socioeconomic status (SES) and gender. Existing gaps in the literature and suggestions for further research are discussed.     

Beyond ‘nothing to hide’: When identity is key to privacy threat under surveillance

Privacy is psychologically important, vital for democracy, and in the era of ubiquitous and mobile surveillance technology, facing increasingly complex threats and challenges. Yet surveillance is often justified under a trope that one has ‘nothing to hide’. We conducted focus groups (N = 42) on topics of surveillance and privacy and using discursive analysis, identify the ideological assumptions and the positions that people adopt to make sense of their participation in a surveillance society. We find a premise that surveillance is increasingly inescapable, but this was only objected to when people reported feeling misrepresented, or where they had an inability to withhold aspects of their identities. The (in)visibility of the surveillance technology also complicated how surveillance is constructed. Those interested in engaging the public in debates about surveillance may be better served by highlighting the identity consequences of surveillance, rather than constructing surveillance as a generalised privacy threat.     

Thinking high but feeling low: An exploratory cluster analysis investigating how implicit and explicit spider fear co-vary

Research has demonstrated large differences in the degree to which direct and indirect measures predict each other and variables including behavioural approach and attentional bias. We investigated whether individual differences in the co-variance of “implicit” and “explicit” spider fear exist, and whether this covariation exerts an effect on spider fear-related outcomes. One hundred and thirty-two undergraduate students completed direct and indirect measures of spider fear/avoidance, self-report questionnaires of psychopathology, an attentional bias task, and a proxy Behavioural Approach Task. TwoStep cluster analysis using implicit and explicit spider fear as criterion variables resulted in three clusters: (1) low explicit/low implicit; (2) average explicit/high implicit; and (3) high explicit/low implicit. Clusters with higher explicit fear demonstrated greater disgust propensity and sensitivity and less willingness to approach a spider. No differences between clusters emerged on anticipatory approach anxiety or attentional bias. We discuss results in terms of dual-systems and cognitive–behavioural models of fear.     

Measuring episodic memory: A novel approach with an indefinite number of alternative forms

Both clinical practice and clinical research settings can require successive administrations of a memory test, particularly when following the trajectory of suspected memory decline in older adults. However, relatively few verbal episodic memory tests have alternative forms. We set out to create a broad‐based memory test to allow for the use of an essentially unlimited number of alternative forms. Four tasks for inclusion in such a test were developed. These tasks varied the requirement for recall as opposed to recognition, the need to form an association between unrelated words, and the need to discriminate the most recent list from earlier lists, all of which proved useful. A total of 115 participants completed the battery of tests and were used to show that the test could differentiate between older and younger adults; a sub‐sample of 73 participants completed alternative forms of the tests to determine test–retest reliability and the amount of learning to learn. Copyright © 2009 John Wiley & Sons, Ltd.     

Proactively performing teams: The role of work design,transformational leadership,and team composition

This study investigated the determinants of team proactive performance amongst 43 shift teams from a UK chemical processing plant. Using external ratings of team proactive performance, the study found that the most proactive teams were those with higher levels of self‐management, transformational team leaders, and a higher‐than‐average level of proactive personality. The relationship between transformational leadership and team proactive performance was mediated by favourable interpersonal norms. In addition, lower diversity of proactive personality amongst team members had an indirect association with team proactive performance via its negative effect on favourable interpersonal norms.