条件性恐惧记忆消退返回的性别差异

采用预期判断任务考察男女性对已消退的条件性恐惧记忆是否会出现消退返回的现象。结果表明: (1)在对已习得的条件性恐惧记忆消退后4个小时进行测试, 被试整体会出现明显的消退返回现象; (2)对消退返回现象的性别差异进行比较, 女性比男性的消退返回现象更突出, 并且差异显著; (3)与男性相比, 女性对条件性恐惧记忆具有易习得难消退的趋势, 但是性别差异不显著。研究结果验证了消退返回现象存在的普遍性, 并且有着显著的性别差异, 为以后对创伤后应激障碍患者的治疗应考虑性别因素提供了心理学依据。     

催产素及受体基因与社会适应行为

作为一种在哺乳动物分娩和泌乳中起神经调节作用的激素, 催产素(oxytocin, OT)在人类的母婴关系和社会关系中也发挥着重要作用。研究发现催产素及其受体基因与人类的社会适应行为关系密切。催产素会影响亲子依恋和父母教养行为, 也能促进人际信任及慷慨行为; 同时, 不同催产素受体(oxytocin receptor, OXTR)基因型的个体, 在亲子关系和一些亲社会行为方面都表现出了差异。来自于激素和基因水平的研究提示我们, 催产素及其受体基因可能是通过促进社会识别、调节共情以及降低恐惧、减缓焦虑来影响人类一系列的社会适应行为。未来的研究应考虑结合分子遗传学和神经科学的研究方法, 从基因－激素－行为三个层面系统的研究催产素影响社会行为的分子过程和认知神经过程。     

Taking a long look at action and time perception

Everyone has probably experienced chronostasis, an illusion of time that can cause a clock's second hand to appear to stand still during an eye movement. Though the illusion was initially thought to reflect a mechanism for preserving perceptual continuity during eye movements, an alternative hypothesis has been advanced that overestimation of time might be a general effect of any action. Contrary to both of these hypotheses, the experiments reported here suggest that distortions of time perception related to an eye movement are not distinct from temporal distortions for other kinds of responses. Moreover, voluntary action is neither necessary nor sufficient for overestimation effects. These results lead to a new interpretation of chronostasis based on the role of attention and memory in time estimation.     

抗菌药物的围手术期预防性应用

手术部位感染在所有医院感染中占第三位,大肠埃希菌、金黄色葡萄球菌、铜绿假单胞菌、表皮葡萄球菌和肠球菌属是主要病原菌,是外科临床十分关心的问题,围手术期预防使用抗菌药物能降低外科部位感染的发生率。在围手术期使用抗菌药物中,应针对不同部位的手术以及可能的病原体以及本院或本地区病原体药物的敏感性选择抗菌药物,同时应注意给要时间应在手术前30min-1h静脉使用足量抗菌药物,以保持抗菌药物的有效浓度覆盖整个手术过程。预防手术部位感染同时应关注其他综合性预防措施。     

伏隔核和中脑腹侧被盖区内食欲素在吗啡奖赏中的作用

实验采用条件性位置偏爱（CPP）模型考察中脑腹侧被盖区（VTA）和伏隔核壳区（NAcSh）内食欲素（orexin）在吗啡奖赏中的作用。Wistar大鼠分为盐水训练组和吗啡训练组。3轮吗啡（或盐水）匹配训练前,双侧VTA或NAcSh内给予OXR1拮抗剂SB334867（VTA: 0, 1, 5μg;NAcSh: 0, 1, 3μg）;或2轮吗啡（或盐水）匹配训练前NAcSh内给予orexin A（0, 2, 4, 6μg）,观察其对吗啡CPP建立的影响。结果表明,VTA内给予SB334867抑制吗啡CPP建立,并存在剂量效应关系;NAcSh内给予SB334867或orexin A均未影响吗啡CPP建立,而orexin A可增加吗啡处理大鼠的运动性。以上结果表明,VTA和NAcSh内的orexin在吗啡奖赏中扮演的角色不同,可能调控成瘾行为的不同成分     

唐山市三甲医院住院费用的灰色关联分析

利用灰色关联分析方法探索引起“看病贵”的主要因素,并提出有效的策略和措施。以唐山市2所三甲医院2004年出院的800名住院患者的医疗费用为研究对象,利用灰色关联分析法进行分析。提出灰色关联模型更加科学和合理;药费是造成外科疾病医疗费用过高的关键因素;需进一步改革医疗服务价格体系。     

Frequency of verb use in young children who stutter

Several recent studies have suggested that young children who stutter (CWS) tend to show depressed lexical performance relative to peers. Given the developmental literature as well as several studies of verb processing in individuals who stutter, verbs may pose a particular challenge for this group. The purpose of the present study was to examine verb use in CWS. In theory, if young CWS differ in their production of verbs, this finding would partially explain the findings of studies that probed conversational vocabulary skills more generally. Fifteen CWS and 15 children who do not stutter (CWNS) participated in a play-based conversational sample with a parent. Samples were analyzed for the total number of verbs, the number of different verbs, and the proportion of general all-purpose (GAP) verbs within the samples. CWS produced significantly fewer different verbs and total verbs than the CWNS. However, previously reported near-significant differences in utterance length between groups would appear to temper the robustness of this finding. The groups did not differ in the proportion of GAP verbs used, suggesting that the CWS did not over-rely on GAP verbs in conversational language production but rather used these verbs to the same extent as their peers. Educational objectives: As a result of this activity, the participant will be able to: (1) relate the purpose and rationale for examining verb use in children who stutter (CWS); (2) summarize the procedures used to assess verb use and GAP verb use in the present study; (3) explain the findings of the present study; (4) relate findings to the extant literature on lexical diversity in CWS.     

The time course of attentional and oculomotor capture reveals a common cause

Eye movements are often misdirected toward a distractor when it appears abruptly, an effect known as oculomotor capture. Fundamental differences between eye movements and attention have led to questions about the relationship of oculomotor capture to the more general effect of sudden onsets on performance, known as attentional capture. This study explores that issue by examining the time course of eye movements and manual localization responses to targets in the presence of sudden-onset distractors. The results demonstrate that for both response types, the proportion of trials on which responses are erroneously directed to sudden onsets reflects the quality of information about the visual display at a given point in time. Oculomotor capture appears to be a specific instance of a more general attentional capture effect. Differences and similarities between the two types of capture can be explained by the critical idea that the quality of information about a visual display changes over time and that different response systems tend to access this information at different moments in time.     

Anxiety sensitivity, conscious awareness and selective attentional biases in children

The current study investigated whether physical anxiety sensitivity (AS) is associated with selective attentional biases to affective stimuli in children. The dot-probe paradigm was used to examine the deployment of attention towards words pertaining to anxiety symptomatology, socially threatening words, and positive words, in samples of 8-10-year-old children. Word pairs were presented under both masked and unmasked conditions. Irrespective of masking, children high in physical AS displayed an attentional vigilance for emotional words relative to neutral words, whereas those low in physical AS displayed a relative avoidance of such material. The results of this study are interesting as they not only suggest the presence of automatic AS-related biases in childhood, but that this is a general emotionality bias rather than one related to specific anxiety-related stimuli.     

视知觉无意识对局部形状和颜色特征加工的注意调节

研究了视知觉无意识对局部几何特征加工中的整体优势效应.被试为天津师范大学本科生60名.仪器为pentium III高分辨率计算机,程序用E-prime心理实验软件系统编制而成.被试的任务是判断靶图形中央线条的方向或颜色.用MANOVA分析了启动图形对靶图形局部特征加工的启动效应,发现了视知觉对无意识呈现的图形加工具有形状优势效应,启动图形与靶图形的整体形状相同可以抑制对靶图形局部形状特征的判断.当被试的任务变成判断靶线条的颜色或启动图形的边由连通状态变成不连通时,视知觉无意识对启动图形加工的整体优势效应消失.该结果提示整体优势效应很可能与任务涉及的信息通道密切相关,对局部形状特征的注意很可能涉及对周围整体形状信息加工自动抑制的过程.