<Emphasis Type="Italic">Æternus Est:</Emphasis> Divinity as a Conceptual Necessity in the Principle of Causation

The modern belief that mindless forces can be ultimate efficient causes of natural events is a conceptual impossibility. The logically ultimate cause of any change, the something that is ultimately making it occur in the present moment, is either a mind or not. More specifically, the cause either chooses to act or it does not. By choice here, I mean an act of free will in the libertarian sense. Where there is choosing in this sense there must be a mind. And when we say that an agent acts thus freely, we mean that it acts without being causally determined to act by anything beyond itself. However, this is conceptually indistinguishable from the idea of an ultimate efficient cause. To say that an agent is the ultimate cause in a causal chain is, by definition, to say that it acts without being caused to act by anything beyond itself. It is the head of the causal chain. It is, therefore, a matter of conceptual necessity that ultimate causes be minds, a fact that we have been blind to since the Scientific Revolution on the bad analogy of machines. Thus, every force ultimately governing the universe must be a mind corresponding either to the polytheist’s or the monotheist’s generic definition of divinity, and monotheism’s eternal mind will always be the most complete and justifiable explanation for the existence of the universe as a whole, even for the existence of the gods themselves.     

Why is the receipt of social support associated with increased psychological distress? an examination of three hypotheses

Abstract

Although there is a great deal of research linking social support with favourable psychological well-being outcomes a number of contradictory findings have been published showing support to be associated with increased psychological distress. These contrary findings arise when social support is measured as the receipt of supportive behavior rather than perceptions of support availability and quality. This paper examines three hypotheses that have been advanced to explain why the receipt of support is associated with distress. The first of these hypotheses (the support mobilisation hypothesis) argues that the relationship is a spurious one, and that it is a product of distressing circumstances which increase both support receipt and psychological distress. The other two hypotheses (the inequity hypothesis and the esteem threat hypothesis) both argue that receiving support actually causes distress. We tested these hypotheses in two samples. One sample was a group of individuals who reported having some form of disability (N = 106). the other sample was a 'healthy' comparison group (N = 134). Our analyses showed that in both groups the receipt of support was significantly and positively related to reports of anxiety, but not to reports of depression. Among the 'healthy' sample, controlling for subjects' sex largely explained the positive association between support receipt and anxiety. This was not the case among the 'disabled sample, where the inequity hypothesis received the strongest support. The implications of these findings for interventions based around the provision of social support are examined.     

Time Doesn’t Change Everything: The Longitudinal Course of Distress Tolerance and its Relationship with Externalizing and Internalizing Symptoms During Early Adolescence

Although distress tolerance is an emerging construct of empirical interest, we know little about its temporal change, developmental trajectory, and prospective relationships with maladaptive behaviors. The current study examined the developmental trajectory (mean- and individual-level change, and rank-order stability) of distress tolerance in an adolescent sample of boys and girls (N?=?277) followed over a four-year period. Next we examined if distress tolerance influenced change in Externalizing (EXT) and Internalizing (INT) symptoms, and if EXT and INT symptoms in turn influenced change in distress tolerance. Finally, we examined if any of these trends differed by gender. Results indicated that distress tolerance is temporally stable, with little mean- or individual-level change. Latent growth models reported that level of distress tolerance is cross-sectionally associated with both EXT and INT symptoms, yet longitudinally, only associated with EXT symptoms. These results suggest that distress tolerance should be a focus of research on etiology and intervention.     

Generalizing Kant's Distinction between Perfect and Imperfect Duties to Trust in Different Situations

Based on previous research that violations of perfect duties cause stronger correspondent inferences than violations of imperfect ones, the authors performed four experiments to generalize this effect to trust. In Experiment 1, abstract violations of perfect duties resulted in less trust than violations of imperfect ones for specific trust scenarios. In Experiments 2 and 3, the authors experimented with different levels of abstractness of the duty violations and obtained similar effects. Experiment 4 was concerned with generalizing further—from duty violations in one situation to trust in a different situation. Although mostly consistent with the findings from Experiments 1–3, the data also demonstrated partial generalization for violations of both perfect and imperfect duties.     

Trajectories and predictors of developmental skills in healthy twins up to 24 months of age

Background

Low birth weight and low 5-min Apgar scores have been associated with developmental delay, while older maternal age is a protective factor. Little is known about trajectories and predictors of developmental skills in infant twins, who are generally born with lower birth weights, lower Apgar scores and to older mothers.

Methods

Developmental skills were assessed at 3, 6, 9, 12, 18 and 24 months using the Ages and Stages Questionnaires in 152 twins from the Birmingham Registry for Twin and Heritability Studies. Multilevel spline and linear regression models (adjusted for gestational age, gender, maternal age) were used to estimate developmental trajectories and the associations between birth weight, maternal age and Apgar scores on developmental skills.

Results

Twins performed worse than singletons on communication, gross motor, fine motor, problem solving and personal-social skills (p < 0.001). Twins caught up around 6 months (score within −1 standard deviation of norm), except on gross motor skills, which did not catch up until after the age of 12 months. A one-year increase in maternal age was significantly associated with decreases in gross motor and personal–social z-scores of up to −0.09, whereas one unit increases in Apgar score increased z-scores up to 0.90 (p < 0.01).

Conclusions

Healthy twins should be considered at a higher risk for developmental delay. Whether these results are comparable to preterm singletons, or whether there are twin-specific issues involved, should be further investigated in a study that uses a matched singleton control group.     

Are You Kynd? Conformity and Deviance Within the Jamband Subculture

I use measures of interpersonal involvement specific to differential association theory to explain variation within the jamband subculture. Specifically, I examine the relationship between the differential association modalities (frequency, intensity, priority, and duration) and the affective meanings (evaluation, potency, and activity) associated with six behaviors that are relevant to that subculture. I expect the modalities to be related positively to the evaluation and potency of four prosocial (what I term “kynd”) behaviors (to barter, to follow a band, to share, to trade music) and negatively to the evaluation and potency of two “unkynd” behaviors (to talk down, to threaten). Using data from self-administered surveys (n = 379), I find that frequency and intensity predict variation in the affective meaning of kynd and unkynd behaviors. However, priority and duration generally do not predict variation in the affective meaning of kynd and unkynd behaviors.     

Oxytocin Receptor Gene Relates to Theory of Mind and Prosocial Behavior in Children

Individual social differences have been addressed in recent studies, and the oxytocin receptor gene (OXTR) is the major candidate in explaining various social phenotypes. To study the association between a well-known haplotype (rs53576) of OXTR and children's prosocial behavior and its relationship with theory of mind (ToM) ability, 87 children (aged 3 to 5 years old) participated in 3 prosocial tasks and ToM performance experiments. Participants who were homozygous for the G allele (GG) exhibited more prosocial behaviors than did those with 1 or 2 copies of the A allele (AA), and GG carriers also displayed better ToM ability than did AA individuals. Further tests showed differences between genotypes in helping and comforting, albeit not in sharing. The results demonstrated that OXTR rs53576 was related to individual differences in ToM and was associated with prosocial behavior.     

胚胎期可卡因、吗啡暴露影响子代成瘾相关行为的神经发育机制

孕期使用毒品可影响胎儿大脑的正常发育,导致脑内神经递质系统异常以及行为的改变.近年来不断有研究证据提示,胚胎期接触可卡因、吗啡等成瘾药物,可以影响神经细胞的增殖、迁移或凋亡等发育过程,使中脑皮层边缘系统中多巴胺、GABA、谷氨酸等神经元形态、受体功能以及突触可塑性发生改变,从而导致子代的学习记忆和成瘾易感性等行为异常.本文将从行为、神经发育、递质系统以及脑功能等层面归纳胚胎期用药对成瘾相关行为影响机制的重要研究进展,并试图提出可能的研究展望.     

药物成瘾诱导相关大脑核团功能和行为改变的DNA甲基化机制

药物成瘾会导致相关神经环路的结构和功能长期改变.大量新的研究证据表明,在DNA序列不变的情况下,药物成瘾可通过影响不同亚型DNA甲基转移酶(DNMTs)的表达,使脑内多个相关核团发生DNA甲基化以及基因表达的改变,进而导致神经元功能的可塑性变化.因此,DNA甲基化被视作导致成瘾行为长期存在的可能机制之一.结合近几年来的重要发现,本文将重点讨论相关脑区的DNA甲基化在成瘾行为发生发展过程中的作用,以及成瘾药物影响DNA甲基化水平的可能机制,并试图提出可深入的研究展望.     

An outline explanation of how therapy heals

Therapists are unable to provide a comprehensive account of therapy as an intelligible activity. This is at least partly due to the unresolved problem of explaining how phenomenology is even possible. An alternative to providing a comprehensive account of therapy is to take the fact of phenomenology for granted and provide just an outline account of how therapy heals. One way this can be achieved is to set therapy in the context of medical anthropology which will facilitate a view of therapy as just another healing ritual. Insight into how healing rituals heal is provided in this paper by a long and in-depth look at the so-called ‘paradox’ of the placebo effect. This will reveal the so-called ‘placebo effect’ as a misunderstood, modern example of healing ritual self-healing. In fact, the single term ‘placebo effect’ will be abandoned and replaced by the two concepts of ‘SMCH’ (‘specifically modified consultation and health care’) and ‘RMH’ (‘response to modified health care’). These two concepts provide an outline explanation of how all healing rituals heal and so provide an outline explanation of how the healing ritual of therapy heals, also. At least one problem arises out of explaining therapy as healing ritual self-healing, namely that this conception conflicts with the idea in therapy circles that, in therapy, it is the relationship that counts. Nonetheless, it will be maintained that the purpose of therapy is healing, that the healing that is achieved is self-healing and that its fulfilment is not dependent upon one-to-one relationships. Finally, it will be argued that the further development of therapy requires a better understanding of what aids and obstructs psycho-emotional self-healing.