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411.
412.
不同相关线索下海洛因成瘾者的反应差异及反应抑制特征:来自ERP的证据 总被引:1,自引:0,他引:1
采用ERP技术, 探究海洛因成瘾者在不同相关线索下的脑电反应及其与冲动性的关系。实验采用组间实验设计和双选择Oddball范式, 要求海洛因成瘾组和健康对照组被试对标准刺激与偏差刺激分别做不同的按键反应, 记录他们的EEG数据。结果发现:相比对照组被试, 海洛因成瘾者在观看药物相关线索时诱发的N2波幅更小, P3波幅更大; 在成瘾组内, 相比用药工具线索, 用药动作线索诱发了更小的N2波幅和更大的P3波幅。这表明海洛因成瘾者对药物相关线索存在反应抑制缺陷, 且不同的药物相关线索会激发海洛因成瘾者不同程度的反应抑制缺陷, 用药动作线索比用药工具线索更大程度地影响成瘾者的反应抑制能力, 反映出更高的动作冲动性。 相似文献
413.
Ethanol has complex effects on memory performance, although hippocampus-dependent memory may be especially vulnerable to disruption by acute ethanol intoxication occurring during or shortly after a training episode. In the present experiments, the effects of post-training ethanol on delay and trace fear conditioning were examined in adolescent rats. In Experiment 1, 30-day-old Sprague-Dawley rats were given delay or trace conditioning trials in which a 10s flashing light CS was paired with a 0.5 mA shock US. For trace groups, the trace interval was 10 s. On days 31-33, animals were administered ethanol once daily (0.0 or 2.5 g/kg via intragastric intubation), and on day 34 animals were tested for CS-elicited freezing. Results showed that post-training ethanol affected the expression of trace, but had no effect on delay conditioned fear. Experiment 2 revealed that this effect was dose-dependent; doses lower than 2.5 g/kg were without effect. Experiment 3 evaluated whether proximity of ethanol to the time of training or testing was critical. Results show that ethanol administration beginning 24h after training was more detrimental to trace conditioned freezing than administration that was delayed by 48 h. Finally, in Experiment 4 animals were trained with one of three different trace intervals: 1, 3 or 10s. Results indicate that post-training administration of 2.5 g/kg ethanol disrupted trace conditioned fear in subjects trained with a 10s, but not with a 1 or 3s, trace interval. Collectively the results suggest that ethanol administration impairs post-acquisition memory processing of hippocampus-dependent trace fear conditioning. 相似文献
414.
Tara M. Madhyastha Earl Hunt Ian J. Deary Catharine R. Gale Dominika Dykiert 《Intelligence》2009,37(4):422-427
In longitudinal studies data is collected in a series of waves. Each wave after the first suffers from attrition. Therefore it can be difficult to discriminate between changes in sample parameters due to a longitudinal process (e.g. ageing) and changes due to attrition. The problem is particularly vexing if one of the purposes is to compare differences between two or more groups over time, because there may be differential attrition across groups. We refer to this as a recruitment problem, because the sample studied in any wave after the first can be thought of as having been recruited from a preceding wave. We present a mathematical model of the recruitment process. We then apply it to two large longitudinal studies, the British Cohort Survey 1970 and the National Child Development Study (1958), to demonstrate how we can identify effects expected from recruitment alone. As an illustration we show that differential recruitment would predict increasing differences between estimates of men's and women's intelligence as the studied sample ages. 相似文献
415.
While cognitive-behavioral therapy for IBS is quite effective, the limited availability of competent therapists and lack of access to treatment remain problematic. This paper reports on a small, randomized, controlled trial of a five week internet based cognitive-behavioral intervention for IBS with limited therapist feedback via e-mail. Fifty-four IBS patients were recruited via the internet and randomly assigned to either immediate treatment or a wait-list control group. Thirty-one subjects completed the post-treatment assessment. 77% of treatment completers also completed a 3-month follow-up assessment. Treatment completers experienced statistically and clinically significant declines in IBS symptoms and improvements in quality of life. Those gains were substantially maintained at follow-up. Treatment efficacy was partially mediated by reductions in the tendency to catastrophize the social and occupational implications of symptoms, suggesting that catastrophizing may be an important target for treatment. 相似文献
416.
Xinyue Zhou Liwei Zheng Lixing Zhou Nan Guo 《Journal of experimental social psychology》2009,45(1):44-50
Through three experiments we examined whether the act of rejecting reduces the desire to reconnect with others. In Experiment 1, female participants who had just rejected a job applicant were less motivated to make new friends than the controls. In Experiment 2, female participants who had insufficient justifications to reject a paper were more reluctant to work with others than those who had sufficient justifications to reject. In Experiment 3, high-choice female participants showed more reduction in reconnecting desire than low-choice female participants. Furthermore, female participants who could misattribute their discomfort away showed less reduction in reconnecting desire. However, in all three experiments, male participants showed less reduction in reconnection desire than females. A follow-up survey showed that males and females differed in their senses of social connectedness and their different discomfort level at rejecting others. Overall, results supported the cognitive dissonance account which posits that, because the act of rejecting is in conflict with the fundamental motive to affiliate, such conflict may compel the mind to modify the existing attitude. Thus rejecting reduces the desire to forge new social connections. 相似文献
417.
In most studies comparing trace and delay conditioning, CS duration is kept constant across training conditions but the interstimulus interval (ISI), the time from CS onset to US onset, is confounded. In the infrequently used long-delay condition, however, ISI is kept constant across the trace and delay conditions but CS duration varies. A recent study reported that trace and long-delay fear conditioning have the same developmental trajectory, with both emerging later in development than standard-delay conditioning (). Past studies have shown that trace conditioning is mediated by the cholinergic system; given the parallel developmental emergence of trace and long-delay conditioning, the present study examined whether the cholinergic system also mediates long-delay conditioning. Two experiments, both involving Sprague-Dawley-derived rats and using freezing as a measure of learned fear, showed that the cholinergic system is critically involved in trace conditioning but is not involved in long-delay conditioning. Specifically, pre-training injections of the muscarinic receptor antagonist scopolamine impaired acquisition of a CS-US association in 32-day-old rats trained with a trace procedure but had no effect on rats this age trained with a long-delay procedure (Experiment 1). Similarly, pre-training injections of physostigmine, a cholinesterase inhibitor, enhanced acquisition of trace conditioning in 25-day-old rats but had no effect on long-delay conditioning in rats this age (Experiment 2). Taken together, the results indicate that despite the similarities between trace and long-delay conditioning in terms of developmental emergence and level of conditioned responding, they are mediated by different physiological systems. 相似文献
418.
419.
《吕氏春秋》包含有丰富的道德心理思想。它对构成个体道德心理的各因素、赏罚的作用、个体道德修养的途径,以及影响个体道德的众多社会因素都有深刻的认识与精辟的见解,值得今人借鉴。 相似文献
420.
对1222名青少年进行六个月的追踪测查,以探讨父母自主支持、父母心理控制和青少年网络成瘾之间的相互预测关系。结果表明:(1)前、后测父母自主支持均与网络成瘾呈负相关。(2)前、后测父母心理控制均与网络成瘾呈正相关。(3)前测父母自主支持可以预测后测网络成瘾,前测网络成瘾也可以预测后测父母自主支持。(4)前测父母心理控制可以预测后测网络成瘾,但前测网络成瘾不能显著预测后测父母心理控制。本研究揭示了父母因素与青少年行为之间的相互作用,这对改善青少年网络成瘾有一定的实践意义。 相似文献