Marijuana's effects on human cognitive functions, psychomotor functions, and personality

Marijuana is complex chemically and not yet fully understood, but it is not a narcotic. Like alcohol, marijuana acts as both stimulant and depressant, but it lingers in body organs longer than alcohol. Smoking marijuana can injure mucosal tissue and may have more carcinogenic potential than tobacco. Research has indicated that marijuana intoxication definitely hinders attention, long-term memory storage, and psychomotor skills involved in driving a car or flying a plane. Expectations and past experience with marijuana have often influenced results more than pharmacological aspects have. Marijuana has triggered psychotic episodes in those more vulnerable. Psychological and some instances of physiological dependence on marijuana have been demonstrated. As a psychoactive drug, marijuana surely alters mental functioning. Although it is possible that chronic use of marijuana produces irreversible damage to mind or brain areas, this has not been determined by research.     

The effect of stress on the linguistic generalization of bilingual individuals

Spanish-English coordinate bilinguals were subjects in a GSR linguistic conditioning experiment using strong and mild buzzer conditions and spoken stimuli. Each subject was randomly assigned to one of two lists of words and one of two levels of buzzer sounds. A Spanish word from the Spanish list and an English word from the English list functioned as a conditioned word (CS). The lists were Spanish and English words related semantically and phonemically and unrelated to the CS. Generalization was studied under conscious and unconscious conditions. We found that both buzzer conditions resulted in significantly greater GSR responses to semantic and phonemic words than to words unrelated to the CS. Generalization to semantic words was not significantly greater than to phonemic words. There was a tendency toward greater phonemic than semantic generalization in the strong buzzer condition. The opposite was observed regarding the mild buzzer. The results were the same in both lists and languages. Under a conscious and unstressful condition, generalization to semantic words was found to be more prominent than to phonemic words. This suggests that under normal condition semantic generalization is mediated by conscious cognition. We concluded that strong emotion produces an increase in phonemic, as compared to semantic, generalization in both languages. Hence, primitivization of the subjects' cognitive and linguistic functioning is assumed to have occurred. These results are important in understanding the deleterious effect that stressful situations may have on linguistic functioning and cognition in bilinguals.     

Attentional deficits in head-injured children: An information processing analysis

Attentional problems of closed head-injured (CHI) children were examined using an information processing (IP) approach. Based on Sternberg's (1969) additive factor method (AFM), the study examined attentional processes in terms of four stages and their corresponding task variables. A visual-spatial choice reaction-time task was undertaken with two groups of CHI children (severe and mild to moderate) and corresponding matched control groups. Results indicated that for this task both the CHI and the normal children exhibited a similar mode of linear, sequential information processing. It was found that the severe group was impaired not only in terms of slowed motor execution but also in terms of response selection. This group showed no impairment on the feature extraction, stimulus identification, and motor adjustment stages of processing. No evidence of impairment on any of the stages was found for the mild group. The utility of the AFM and implications of these findings are discussed with reference to CHI children and to neuropsychological assessment and rehabilitation.     

Measuring the stop point of rapid smoking

A method and an apparatus are described for measuring the point at which subjects elect to stop smoking when cigarette smoke is delivered more rapidly than in typical smoking. The device allows either the subject or the experimenter to control the volume of smoke and the interval between puffs. The device delivers reliable quantities of particulate matter from cigarette smoke. Subjects retested a week apart exhibited consistent stopping points.     

Clamped Corticosterone (B) Reveals the Effect of Endogenous B on Both Facilitated Responsivity to Acute Restraint and Metabolic Responses to Chronic Stress

To determine the effects of both corticosterone (B) and chronic stressors on acute ACTH responses to restraint, young male rats were exposed to streptozotocin-induced diabetes, cold (5-7 degreesC) or intracerebroventricular (icv) neuropeptide Y (NPY) for 5 d and then exposed to restraint within 2 h after lights on. Two groups of rats were studied: intact and adrenalectomized replaced with B pellets that maintained plasma B in the normal mean 24-h range of intact rats. In addition to ACTH and B responses to restraint on d 5, body weight, food intake, fat depots, glucose and other hormones were measured to determine the role of stress-induced elevations in B on energy balance. ACTH responses to restraint were normal in intact rats subjected to diabetes or cold. By contrast, there was no ACTH or B response to restraint in NPY-infused intact rats. All 3 groups of chronically stimulated adrenalectomized rats with clamped B had facilitated ACTH responses to restraint compared to their treatment controls. Overall food intake increased in all groups of stressed rats; however, augmented intake occurred only during the light in intact rats and equally in the light and dark in B-clamped rats. White adipose depot weights were decreased by both diabetes and cold and increased by NPY in intact rats; the decreases with cold and increases with NPY were both blunted and changes in fat stores were not significant in adrenalectomized, B-clamped rats. We conclude that: 1. diabetes- and cold-induced facilitation of restraint-induced afferent input to hypothalamic control of the hypothalamo-pituitary-adrenal (HPA) axis is opposed in intact rats by the elevated feedback signal of B secretion; 2. NPY does not induce facilitation of afferent stress pathways; 3. chronic stimulation of the HPA axis induces acute hyperresponsiveness of hypothalamic neurons to restraint provided that the afferent input of this acute stimulus is not prevented by B feedback; 4. stimulus-induced elevations in B secretion result in day-time feeding; 5. insensitivity of both caloric efficiency and white fat stores to chronic stress in adrenalectomized, B-clamped rats results from loss of normally variable B levels.     

The role of working memory capacity and knowledge access in text inference processing

Individual differences in drawing bridging inferences during text comprehension were examined. We measured reader differences in working memory capacity, using the reading span task, and in access to relevant knowledge, using Potts and Peterson’s (1985) integration task. The dependent measure of greatest concern was answer time about facts posited to validate the bridging inference. Reading span and access were negligibly correlated, an outcome that supports their independence. Answer times were lower both for high reading span and high-access readers. In addition, readers who were either high on both reader traits or low on both traits exhibited qualitatively different inference effects from the typical pattern. It is proposed that knowledge access during comprehension is facilitated by the extraction of integrated situation models from text and that it is individuals with efficient reading processes who can construct these models.     

Prosodic form and parsing commitments

This paper examines the question of whether there are effects of prosody on the syntactic parsing of temporarily ambiguous sentences containing complement verbs. It reports the results of five experiments employing cross-modal response tasks where the visually presented target word was either an appropriate or an inappropriate continuation in terms of the prosodic form of the preceeding auditory sentence fragment. Two experiments employing cross-modal naming only showed indications of sensitivity to syntactic and appropriateness manipulations when coupled with a simultaneous appropriateness judgment task. In contrast, the experiments employing cross-modal lexical decision showed greater sensitivity to syntactic and appropriateness effects. However, while the results from these studies replicated our earlier auditory parsing results and provided support for the suggestion that there are differences in visual and auditory parsing processes and for a constituent-based, minimal commitment type auditory parser, none of the studies demonstrated an effect of prosodic form on the parsing process.     

Imagining and naming rotated natural objects

The present experiment examined whether subjects can form and store imagined objects in various orientations. Subjects in a training phase named line drawings of natural objects shown at six orientations, named objects shown upright, or imagined upright objects at six orientations. Time to imagine an upright object at another orientation increased the farther the designated orientation was from the upright, with faster image formation times at 180° than at 120°. Similar systematic patterns of effects of orientation on identification time were found for rotated objects. During the test phase, all subjects named the previously experienced objects as well as new objects, at six orientations. The orientation effect for old objects seen previously in a variety of orientations was much reduced relative to the orientation effect for new objects. In contrast, substantial effects of orientation on naming time were observed for old objects for subjects who had previously seen the objects upright only or upright but imagined at different orientations. The results suggest that the attenuation of initially large effects of orientation with practice cannot be due to imagining and forming representations of objects at a number of orientations.     

Object Recognition Difficulty in Visual Apperceptive Agnosia

Two patients with visual apperceptive agnosia were examined on tasks assessing the appreciation of visual material. Elementary visual functioning was relatively preserved, but they had profound difficulty recognizing and naming line drawings. More detailed evaluation revealed accurate recognition of regular geometric shapes and colors, but performance deteriorated when the shapes were made more complex visually, when multiple-choice arrays contained larger numbers of simple targets and foils, and when a mental manipulation such as a rotation was required. The recognition of letters and words was similarly compromised. Naming, recognition, and anomaly judgments of colored pictures and real objects were more accurate than similar decisions involving black-and-white line drawings. Visual imagery for shapes, letters, and objects appeared to be more accurate than visual perception of the same materials. We hypothesize that object recognition difficulty in visual apperceptive agnosia is due to two related factors: the impaired appreciation of the visual perceptual features that constitute objects, and a limitation in the cognitive resources that are available for processing demanding material within the visual modality.