Peer Victimization in Youth with Tourette’s Syndrome and Chronic Tic Disorder: Relations with Tic Severity and Internalizing Symptoms

The present study analyzed rates of peer victimization in children with a chronic tic disorder as compared to children with type 1 diabetes and healthy controls. The associations among peer victimization, tic symptom severity, and psychological symptoms, as well as the potential mediating relationship between peer victimization, tic severity, and child internalizing symptoms, were also explored. Children with tics displayed higher rates of peer victimization than control groups, and peer victimization in children with tics was positively correlated with tic symptom severity, loneliness, anxiety symptoms, and parent report of child internalizing symptoms. Results also supported the hypothesis that peer victimization mediates the relationship between tic symptom severity and loneliness. Findings highlight the importance of the assessment and treatment of psychosocial variables in children with chronic tic disorders, including social functioning and peer relationships.     

Word-list-learning performance in younger and older adults: intra-individual performance variability and false memory

We investigated the word-list-learning performance of younger and older adults over 4 consecutive days at different times of day to study age-related differences in consistency of performance over time and the influence of circadian variation on performance. Eighteen younger (M age, 23.4 years) and 18 older (M age, 73.3 years) men and women participated. The start time of testing alternated between morning and early evening across the 4 days of testing. On each test day, participants learned a different list of 15 unrelated words over four learning trials. As expected, younger adults performed better than older adults on immediate recall, delayed recall, and recognition. Contrary to our expectations, time of day did not significantly influence recall or recognition performance in either the older or younger adults. Older adults did show a greater incidence of false memory (i.e., previously learned list intrusions in free recall and false alarms in recognition) than younger adults. Older adults also exhibited greater intra-individual performance variability on the measures of false memory across test days. This variability was not related to circadian variation. False memory and variability of performance have both been linked to frontal systems dysfunction. The findings presented here are consistent with the notion that changes in cognition with aging in part reflect age-related decline in frontal lobe function.     

The effect of stimulus delivery technique on perceived intensity functions for taste stimuli: Implications for fMRI studies

Classic psychophysical studies have provided significant information on the psychophysical functions for taste stimuli. With the advent of fMRI, studies are being conducted that provide insight into central processing of gustation in humans. However, fMRI experiments impose physical limitations on stimulus delivery. In the present study, we compared psychophysical functions relating perceived intensity to concentration, derived from previous studies that used the traditional sip-and-spit and dorsal flow delivery techniques, to psychophysical functions generated in this study using a simulated stimulus delivery technique (SSDT). The SSDT delivered minute quantities of taste stimuli to the dorsal surface of the tongue, just as in an fMRI scanner. As was hypothesized, the results indicated that slopes of intensity functions were dependent on the type of stimulus delivery technique. The SSDT resulted in slopes that were more similar to those generated by dorsal flow than by sip-andspit stimulus delivery techniques, suggesting the importance of considering the influence of stimulus delivery on psychophysical response in designing and interpreting experiments.     

Establishing Derived Manding for Specific Amounts with Three Children: An Attempt at Synthesizing Skinner’s Verbal Behavior with Relational Frame Theory

The Psychological Record - Participants were 2 typically developing children, aged 9 and 10 years, and 1 child, aged 4 years, with a reported severe speech delay. Five specific mand functions were...     

The consequences of effortful emotion regulation when processing distressing material: A comparison of suppression and acceptance

The present study investigated the consequences of different forms of emotion regulation. Eighty nine healthy participants viewed a distressing video of the aftermath of road traffic accidents under either suppression (of both felt and expressed affect), acceptance, or no-regulation control instructions and the immediate and longer-term consequences on emotion, mood, and memory were examined. Suppression (relative to control) led to reduced subjective experience of fear when viewing the video, but did not alter electrodermal (EDA) or heart rate (HR) response. Subsequently, suppression led to a less marked subjective emotional reaction to positive but not negative emotional images, reduced free recall memory of the video, and a greater likelihood of experiencing zero intrusions of the video's content. Acceptance (relative to control) had no impact when viewing the video, was associated with a less marked increase in EDA activity in the 5 min period immediately after viewing the video, a more marked HR deceleration and EDA response to both positive and negative images, and elevated negative affect at one week follow-up. These findings suggest, contrary to the current clinical zeitgeist, that emotion suppression can successfully lead to an ongoing down-regulation of emotion and memory, whereas acceptance may elevate subsequent emotionality.     

DERIVED MORE‐LESS RELATIONAL MANDS IN CHILDREN DIAGNOSED WITH AUTISM

In Experiment 1, more and less relations were trained for arbitrary Stimuli A1 and A2 with 3 children with autism. The following conditional discriminations were then trained: A1‐B1, A2‐B2, B1‐C1, B2‐C2. In subsequent tests, participants showed derived more‐less mands (mand with C1 for more and mand with C2 for less). A training procedure reversed the B‐C conditional discriminations, and participants then showed derived reversed more—less mands (mand with C1 for less, C2 for more). Baseline B‐C relations were retrained, and participants subsequently demonstrated a return to the original derived manding. A second experiment with 1 prior participant and 1 naive participant removed a possible confounding effect. Establishing derived manding may be an advantageous component when teaching a mand repertoire in applied settings.     

The Effectiveness of Family History Questionnaires in Cancer Genetic Counseling

The number of individuals receiving genetic counseling for hereditary breast and ovarian cancer syndrome has steadily risen. To triage patients for genetic counseling and to help reduce the amount of time needed by a genetic counselor in direct patient contact, many clinics have implemented the use of family history questionnaires. Although such questionnaires are widely used, scant literature exists evaluating their effectiveness. This article explores the extent to which family history questionnaires are being used in Ontario and addresses the utility of such questionnaires in one familial cancer clinic. By comparing the pedigrees created from questionnaires to those updated during genetic counseling, the accuracy and effectiveness of the questionnaires was explored. Of 121 families recruited into the study, 12% acquired changes to their pedigree that led to a revised probability estimate for having a BRCA1 or BRCA2 mutation and 5% acquired changes that altered their eligibility for genetic testing. No statistically significant difference existed between the eligibility for genetic testing prior to and post counseling. This suggests that family history questionnaires can be effective at obtaining a family history and accurately assessing eligibility for genetic testing. Based on the variables that were significantly associated with a change in probability estimate, we further present recommendations for improving the clarity of such questionnaires and therefore the ease of use by patients.     

Sensitization and habituation regulate reinforcer effectiveness

We argue that sensitization and habituation occur to the sensory properties of reinforcers when those reinforcers are presented repeatedly or for a prolonged time. Sensitization increases, and habituation decreases, the ability of a reinforcer to control behavior. Supporting this argument, the rate of operant responding changes systematically within experimental sessions even when the programmed rate of reinforcement is held constant across the session. These within-session changes in operant responding are produced by repeated delivery of the reinforcer, and their empirical characteristics correspond to the characteristics of behavior undergoing sensitization and habituation. Two characteristics of habituation (dishabituation, stimulus specificity) are particularly useful in separating habituation from alternative explanations. Arguing that habituation occurs to reinforcers expands the domain of habituation. The argument implies that habituation occurs to biologically important, not just to neutral, stimuli. The argument also implies that habituation may be observed in “voluntary” (operant), not just in reflexive, behavior. Expanding the domain of habituation has important implications for understanding operant and classical conditioning. Habituation may also contribute to the regulation of motivated behaviors. Habituation provides a more accurate and a less cumbersome explanation for motivated behaviors than homeostasis. Habituation also has some surprising, and easily testable, implications for the control of motivated behaviors.     

Intensive Family-Based Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder: Applications for Treatment of Medication Partial- or Nonresponders

Serotonin reuptake inhibitor medications and cognitive-behavioral therapy (CBT) are both effective treatments for pediatric obsessive-compulsive disorder (OCD). Despite recommendations that youth with OCD be treated with CBT alone or together with serotonin reuptake inhibitor medication, many youth are treated with medication alone or with non-CBT psychotherapy initially. Although effective, symptom remission with medication alone is rare (e.g., only 21.4% of youth achieved remission with sertraline in the Pediatric OCD Treatment Study, 2004) and residual symptoms often remain (e.g., 58% of subjects in the March et al. [1998] sertraline trial were not considered treatment responders). This paper reviews the literature on the efficacy of CBT for pediatric OCD, particularly as it relates to the treatment of youth with prior inadequate response to medication. It also describes an intensive, family-based CBT program for children and adolescents with OCD and support for its efficacy among those with prior partial- or nonresponse to medication. Finally, we present a case study of an adolescent girl with OCD who participated in the intensive treatment program after having limited benefit from medication and non-CBT psychotherapy and experienced a favorable response.