Pantagruelism: A Rabelaisian inspiration for Understanding Poisoning,Euthanasia and Abortion in The Hippocratic Oath and in Contemporary Clinical Practice

Contrary to the common view, this paper suggests that the Hippocratic oath does not directly refer to the controversial subjects of euthanasia and abortion. We interpret the oath in the context of establishing trust in medicine through departure from Pantagruelism. Pantagruelism is coined after Rabelais' classic novel Gargantua and Pantagruel. His satire about a wonder herb, Pantagruelion, is actually a sophisticated model of anti-medicine in which absence of independent moral values and of properly conducted research fashion a flagrant over-medicalization of human problems. Ultimately this undermines the therapeutic core of medicine itself. We contend that PAS is a case of such over-medicalization and that its institution creates medicophobia. This article does not express an opinion about euthanasia in general. Rather, we claim that physicians should learn from the oath and from Rabelais that they should keep their practice to medical care and not to exploit their expertise and social privileges for the sake of ulterior motives, even when their patients desire those goals.     

Revisiting the definition of homo sapiens

Research in genomics, human cloning, and transgenic technology has challenged bioethicists and scientists to rethink the definition of human beings as a species. For example, should the definition incorporate a genetic criterion and how does the capacity to genetically engineer human beings affect the definition of our species? In considering these contemporary bioethical dilemmas, we revisit an ancient source, the Talmud, and highlight how it provides specific biological, cultural, and genetic criteria to define the human species.     

Sublimal Visual Priming

Masked pictures of objects were flashed so briefly that only 13.5% of them could be named. Forced-choice accuracy for the unidentified objects was at chance. When the pictures were shown again, about 15 min and 20 intervening trials later, without any indication of possible repetitions, naming accuracy increased to 34.5%. The priming was completely visual, rather than semantic or verbal, as there was no priming of same-name, different-shape images. This is the first demonstration of facilitatory visual recognition priming by unidentified pictures when the subject could not anticipate if, when, or where the previously unidentified picture was to be shown again. A change in the position of the object reduced but did not eliminate the priming, allowing a speculation that the locus of subliminal visual priming is at an intermediate stage in the ventral cortical pathway for shape recognition.     

Prior probability modulates anticipatory activity in category-specific areas

Bayesian models are currently a dominant framework for describing human information processing. However, it is not clear yet how major tenets of this framework can be translated to brain processes. In this study, we addressed the neural underpinning of prior probability and its effect on anticipatory activity in category-specific areas. Before fMRI scanning, participants were trained in two behavioral sessions to learn the prior probability and correct order of visual events within a sequence. The events of each sequence included two different presentations of a geometric shape and one picture of either a house or a face, which appeared with either a high or a low likelihood. Each sequence was preceded by a cue that gave participants probabilistic information about which items to expect next. This allowed examining cue-related anticipatory modulation of activity as a function of prior probability in category-specific areas (fusiform face area and parahippocampal place area). Our findings show that activity in the fusiform face area was higher when faces had a higher prior probability. The finding of a difference between levels of expectations is consistent with graded, probabilistically modulated activity, but the data do not rule out the alternative explanation of a categorical neural response. Importantly, these differences were only visible during anticipation, and vanished at the time of stimulus presentation, calling for a functional distinction when considering the effects of prior probability. Finally, there were no anticipatory effects for houses in the parahippocampal place area, suggesting sensitivity to stimulus material when looking at effects of prediction.     

Topological duality for distributive Ockham algebras

In this note, we give a representation of distributive Ockham algebras via natural hom-functors. In order to do this, we describe two different structures (one algebraic, and the other order-topological) on the set of subsets of the natural numbers. The topological duality previously obtained by A. Urquhart is used throughout.     

Intuitive inventory management: An experimental system

The way people intuitively manage inventories is both an important issue in its own right and a context for research on various basic theoretical questions. The subject has not yet been systematically studied, owing partially to the lack of appropriate research tools. This paper presents some of the key concepts in formal inventory theory and describes an experimental system for the study of intuitive inventory management. This system is a computer program that allows subjects to interact with a simulated inventory system. Numerous system parameters can be manipulated, including demand functions, prices, costs, and the display of data. The usefulness of the system is demonstrated via the study of the effects of three parameters on intuitive inventory management in an illustrative experiment. Possible future uses of the system in basic and applied research and in training are indicated.     

Touched by Grace during the psychoanalytic hour: the transformation of a religious resistance

Case material is presented illustrating a phase in religious transformation in which the quality of the religious moment -first expressed in transference hints and a dream, and finally augmented by an idiosyncratic enactment of the patient's-became sufficiently intense that it crossed formal religious boundaries. The patient resisted direct reference to her religious beliefs, yet the deeper roots of her God representations took alternative forms of expression. The analyst's appreciation of this, which was rendered articulable through a carefully refined countertransference experience, eventually enabled a sincere experience of joining, one that superseded apparent religious differences between analyst and patient.     

Adult age differences in memory for name-face associations: The effects of intentional and incidental learning

Previous studies have indicated that older adults have a special deficit in the encoding and retrieval of associations. The current study assessed this deficit using ecologically valid name-face pairs. In two experiments, younger and older participants learned a series of name-face pairs under intentional and incidental learning instructions, respectively, and were then tested for their recognition of the faces, the names, and the associations between the names and faces. Under incidental encoding conditions older adults' performance was uniformly lower than younger adults in all three tests, indicating age-related impairments in episodic memory representations. An age-related deficit specific to associations was found under intentional but not under incidental learning conditions, highlighting the importance of strategic associative processes and their decline in older adults. Separate analyses of hits and false alarms indicate that older adults' associative deficit originated from high false alarm rates in the associative test. Older adults' high false alarm rates potentially reflect their reduced ability to recollect the study-phase name-face pairs in the presence of intact familiarity with individual names and faces.