The Role of the Family in Promoting Responsible Substance Use in Adolescence

The aim of this study was to examine the role of family dimensions in tobacco, alcohol, and cannabis use among adolescents. Furthermore, we investigated how demographic variables (adolescents’ gender and age) influence substance use and moderate the relationship between family dimensions and substance use. The sample consisted of 14,825 adolescents aged 13–14, 15–16, and 17–18 who participated in the 2006 edition of the Health Behaviour in School-aged Children (HBSC) study in Spain. The HBSC-2006 questionnaire included demographic variables (gender and age), substance use variables (tobacco, alcohol, and cannabis use), and family dimensions (parental affection, parental promotion of autonomy, family activities, adolescent disclosure, parental solicitation, and parental knowledge). The results indicated that adolescent disclosure, family activities, and parental knowledge had a significant effect on substance use. Specifically, maternal variables were shown to be slightly more relevant than paternal variables. Additionally, substance use was higher in older adolescents than in younger adolescents, and boys smoked less than girls. The discussion focused on how family dimensions promoted responsible substance use in adolescence.     

Correlates of Happiness Among Older Spanish Institutionalised and Non-Institutionalised Adults

The overall objective of this study was to explore the current (i.e., at the time of the study) and past (i.e., over their lifetimes) happiness of 65-year-old and older men and women who had different personal and socio-demographic characteristics. We also investigated the role of affect balance and life satisfaction as sources of participants’ subjective well-being, as well as the contribution of other psychosocial variables, including self-efficacy, optimism, health and quality of life, stress, social support and leisure, and of socio-demographic conditions. Further, we examined the influence of institutionalisation on happiness and on the aforementioned psychosocial variables. Participants voluntarily completed self-reports regarding all of these variables. Participants’ current happiness (M = 6.6 on a 0–10 scale) was significantly lower than their past happiness (M = 7.7). The happiness of the institutionalised participants did not differ from that of the non-institutionalised participants, although significant differences were found for a number of psychosocial variables. Affect balance and life satisfaction were significant correlates and predictors of current happiness, which was also associated with many psychosocial variables and was further predicted by past happiness, health indicators and some life dimensions assessed as perceived sources of one’s own happiness, such as a sense of autonomy and independence. Our results highlight the importance of establishing both happiness and its correlates to develop interventions aimed at promoting subjective well-being in older people, given that, compared to earlier periods in life, happiness may be reduced in late adulthood.     

The classification of Spanish adolescents based on substance consumption patterns and the analysis of the relationships within their social developmental contexts

This research is part of the 2006 edition of the Health Behavior in School-aged Children (HBSC) study. The data presented were composed of a sample of 15942 Spanish adolescents ranging from 13 to 18 years of age. The instruments used included a variety of questions related to substance consumption among adolescents, their bio-psycho-social adjustment and developmental contexts, all of which are part of the HBSC study instrument bank. Through classification analysis, as well as significance and effect size tests, we obtained relevant information about the current epidemiology of substance consumption among Spanish adolescents. These results are representative of the Spanish adolescent population which allows the typical risk profile attributed to young people to be clarified. A gradual adjustment can be seen in terms of substance consumption levels in youth and that same level in their friends. Likewise, the analysis of the developmental context (family, friends and school) provides important information when it comes to preventing substance consumption, thus showing the advantages that coherence and connection have between the different environments where youth live, grow up and develop.     

Higher-order structure in the trajectories of depression and anxiety following sudden involuntary unemployment

Recent work on comorbidity finds evidence for hierarchical structure of mood and anxiety disorders and symptoms. This study tests whether a higher-order internalizing factor accounts for variation in depression and anxiety symptom severity and change over time in a sample experiencing a period of major life stress. Data on symptoms of depression, chronic worry, and social anxiety were collected five times across seven months from 426 individuals who had recently lost jobs. Growth models for each type of symptom found significant variation in individual trajectories. Slopes were highly correlated across symptom type, as were intercepts. Multilevel confirmatory factor analyses found evidence for a higher-order internalizing factor for both slopes and intercepts, reflective of comorbidity of depression and anxiety, with the internalizing factor accounting for 54% to 91% of the variance in slopes and intercepts of specific symptom sets, providing evidence for both a general common factor and domain-specific factors characterizing level and change in symptoms. Loadings on the higher order factors differed modestly for men and women, and when comparing African American and White participants, but did not differ by age, education, or history of depression. More distal factors including gender and history of depression were strongly associated with internalizing in the early weeks after job loss, but rates of change in internalizing were associated most strongly with reemployment. Findings suggest that stressors may contribute in different ways to the common internalizing factor as compared to variance in anxiety and depression that is independent of that factor.     

Revising the history of Cold War research ethics

President Clinton's charge to the Advisory Committee on Human Radiation Experiments included the identification of ethical and legal standards for evaluating government-sponsored radiation experiments conducted during the Cold War. In this paper, we review the traditional account of the history of American research ethics, and then highlight and explain the significance of a number of the Committee's historical findings as they relate to this account. These findings include both the national defense establishment's struggles with legal and insurance issues concerning human experiments, and the medical profession's perspective on human experimentation in the years following the Nuremberg Medical Trials. We conclude that the Committee's work both enriches the traditional view of the history of research ethics and opens important new areas for study.     

Effects of social stress on tumor development in dominant male mice with diverse behavioral activity profiles

We examined the influence of individual psychological profile and social behavior on tumor development in dominant male mice. Male OF1 mice were subjected to an open field test (OFT) to observe their motor activity and latency. Subsequently, the animals were divided into three groups: Stress-Non-Inoculated (SNI), Stress-Inoculated (SI) and Control-Inoculated (CI). The SI and CI groups were inoculated with tumor cells and the SNI group with vehicle. SNI and SI were exposed to social stress with an anosmic intruder six (T1) and twenty one (T2) days after inoculation and their behavior was analyzed. After T2, subjects were put down and the pulmonary metastatic foci counted. SI developed greater pulmonary metastasis than CI, indicating an effect of stress despite the animal's dominant status. Active animals developed less pulmonary metastasis than their passive counterparts. No differences were found in social behavior at T1. Differences were found, however, in some behavioral categories at T2 between SI and SNI, and between active and passive animals. These differences indicate an effect of tumor development on social behavior that is more evident in passive subjects.     

The Influence of Clinical Variables on the Psychological Adaptation of Adolescents after Solid Organ Transplantation

This study assessed the influence of clinical and socio-demographic variables on the psychological adaptation of transplanted adolescents. Twenty-six transplanted adolescents and 25 healthy adolescents, aged 13–17, and their parents participated in the study. The following domains were measured: social competence, emotional/behavioral problems, self-concept, self-esteem and subjective well-being. The findings revealed that transplanted boys presented significantly less social competence (U = 26,000, p < .05) and more externalizing problems (U = 25,000, p < .05), social problems (U = 25,000, p < .05) and attention problems (U = 17,500, p < .01) than healthy boys. In contrast, transplanted girls displayed significantly more internalizing problems (U = 47,000, p < .05) and lower physical self-concept (U = 49,500, p < .05) than healthy girls. Hierarchical regression analysis showed clinical variables, especially waiting-list time, significantly predicted attention problems (β = .364, p < .05) and negative affect (β = .632, p < .05) in transplanted adolescents. Also, male (β = −0.554, p < .01) and younger (β = −0.444, p < .01) transplanted adolescents were at risk for attention problems. Our data suggest the importance of the waiting-list time for transplanted adolescents. Efforts to reduce the pretransplant phase would help adolescents achieve better psychological adaptation at long-term posttransplant.