Return of Genetic Results in the Familial Dilated Cardiomyopathy Research Project

The goal of the Familial Dilated Cardiomyopathy (FDC) Research Project, initiated in 1993, has been to identify and characterize FDC genetic cause. All participating individuals have been consented for the return of genetic results, an important but challenging undertaking. Since the inception of the Project we have enrolled 606 probands, and 269 of these had 1670 family members also enrolled. Each subject was evaluated for idiopathic dilated cardiomyopathy (IDC) and pedigrees were categorized as familial or sporadic. The coding regions of 14 genes were resequenced in 311 to 324 probands in five studies. Ninety-two probands were found to carry nonsynonymous rare variants absent in controls, and with Clinical Laboratory Improvement Amendment of 1988 (CLIA) compliant protocols, relevant genetic results were returned to these probands and their consented relatives by study genetic counselors and physicians in 353 letters. In 10 of the 51 families that received results >1 year ago, at least 23 individuals underwent CLIA confirmation testing for their family’s rare variant. Return of genetic results has been successfully undertaken in the FDC Research Project. This report describes the methods utilized in the process of returning research results. We use this information as a springboard for providing guidance to other genetic research groups and proposing future directions in this arena.     

Bodily ownership and self-location: Components of bodily self-consciousness

Recent research on bodily self-consciousness has assumed that it consists of three distinct components: the experience of owning a body (body ownership); the experience of being a body with a given location within the environment (self-location); and the experience of taking a first-person, body-centered, perspective on that environment (perspective). Here we review recent neuroimaging studies suggesting that at least two of these components—body ownership and self-location—are implemented in rather distinct neural substrates, located, respectively, in the premotor cortex and in the temporo-parietal junction. We examine these results and consider them in relation to clinical evidence from patients with altered body perception and work on a variety of multisensory, body-related illusions, such as the rubber hand illusion, the full body illusion, the body swap illusion and the enfacement illusion. We conclude by providing a preliminary synthesis of the data on bodily self-consciousness and its neural correlates.     

Spiritual Coping in American Buddhists: An Exploratory Study

Researchers in the United States have examined spiritual coping in Christians, Jews, Hindus, and Muslims, but rarely Buddhists. Using qualitative methodology, the present study represents an initial investigation into Buddhist forms of coping. Twenty-four Buddhists from across the United States were interviewed by phone, examining how their spirituality is used to cope with stress. Thematic analyses revealed six forms of Buddhist coping—right understanding, meditation, mindfulness, spiritual struggles, morality, and finding support in one's sangha. Implications of the study are discussed, including possibilities for future research on Buddhist coping.     

Traditional Healing as Indigenous Knowledge: Its Relevance to HIV/AIDS in Southern Africa and the Implications for Counselors

This article integrates the results of several culture-based studies conducted over the past decade. Specifically, links are made between the continued relevance of the African traditional healer's corpus of knowledge, the efficacy of the healer's cultural authority, and the need for HIV/AIDS-related strategies and interventions that are culturally sensitive, especially counseling. Results of an initial investigation of traditional healing in Lesotho, Swaziland, and Zimbabwe are integrated with more recent research in Botswana and Namibia. Findings from these studies are meshed with preliminary results of an ongoing investigation of the contextual influences and cultural factors associated with the spread of HIV/AIDS in the southern African region. Outcomes of the combined investigations have supported further examination of traditional healing as an indigenous knowledge system, of its relevance to HIV/AIDS, and of its significance to professional counselors in Africa. Related recommendations are offered for consideration by those working within HIV/AIDS systems of intervention.     

Fostering Self-Determination and Resilience Through Sports Counselling: Psychosocial Development of Youth in Botswana

Sports can promote pro-social behaviors and confidence in physical abilities among participants. We conducted an extensive review of the literature on the ways in which youth in Southern African countries, severely affected by the HIV/AIDS pandemic and other hardships may benefit from acquiring the pro-social skills often associated with athletics. This article reviews the current situation of sports in Botswana and offers recommendations for a culturally appropriate developmental sports counselling program in that country. The authors present arguments that support the development of psychosocial skills, self-determination, and resilience among Batswana Youth through sports counselling interventions.     

What COP and Kinematic Parameters Better Characterize Postural Control in Standing Balance Tasks?

The authors’ aim was to determine which variables allow for the characterization of motor balance behavior. Traditional measures and nonlinear measures of center of pressure (COP; n = 30) and kinematics (n = 10) were tested in their absolute and relative consistency in a 30-s standing balance task protocol under stable and unstable conditions. Regarding COP variables, mean velocity (mVel), permutation entropy (PE) and detrended fluctuation analysis (DFA) exhibited high consistency between trials and ranked individuals more accurately compare with other metrics. In the kinematic signal mVel, PE and DFA had good intrasession reliability values in unstable conditions. Overall, the intrasession reliability values were better in the unstable condition than in the stable condition and the measures calculated using derived data had better intrasession reliability values. In conclusion, mVel, PE, and DFA allow for the good characterization of motor balance behavior in a simplified protocol where velocity time series are analyzed.     

Suffering by comparison: Twitter users’ reactions to the Victoria's Secret Fashion Show

Social comparison theory suggests that evaluating the self in comparison with others (e.g., peers, celebrities, models) can influence body image. Experimental studies that have tested effects of viewing idealized images in the media often show that women feel worse about themselves after seeing images that illustrate the beauty ideal. Twitter presents a naturally occurring opportunity to study viewers’ reactions. An analysis was conducted of 977 tweets sent immediately before and during the 2011 Victoria's Secret Fashion Show that reference the show. Although the majority were idiosyncratic remarks, many tweets contain evidence of upward social comparisons to the fashion models. There were tweets about body image, eating disorders, weight, desires for food or alcohol, and thoughts about self-harm. The results support social comparison theory, and suggest that vulnerable viewers could experience negative affect, or even engage in harmful behaviors, during or after viewing the show or others like it.     

Therapists’ perspectives about working with meaning in life in psychotherapy: A survey

Of 212 practicing therapists who completed a survey about working with meaning in life (MIL) in psychotherapy, 129 (61%) had recently worked with MIL with at least one client and reported on their work with a client in this survey. Those therapists who had worked with a client on MIL as compared with those who had not were older, more experienced, more humanistic/existential/experiential in orientation; reported more MIL training; and felt more competent working with MIL. Clients reported on primarily had internalizing, interpersonal, and career issues. Only 12% of clients explicitly labeled MIL as an issue coming into therapy. The three most frequently used interventions involved offering support; helping clients examine thoughts, feelings, and behaviors to discover hopes and goals; and facilitating exploration of MIL cognitions and experiences. Therapists reported many positive consequences from working with MIL. Therapists reported minimal training in MIL and moderate competence in working with MIL. Implications for practice, training, and research are presented.     

Ethical Guidelines for Mass Trauma and Complex Humanitarian Emergencies

Issues pertaining to trauma, especially mass trauma and complex humanitarian emergencies, are explored through the lens of ethical counseling guidelines. In mass trauma, particular attention must be paid to the experiences of both survivors and counselors to enhance understanding of ethical best practices and to emphasize the importance of contextual factors in framing effective responses to trauma and humanitarian crises. Recommendations regarding ethical guidelines for counseling practice, clinical involvement, and training are offered.     

The Gettier Intuition from South America to Asia

Journal of Indian Council of Philosophical Research - This article examines whether people share the Gettier intuition (viz. that someone who has a true justified belief that p may nonetheless fail...