More intelligent, more dependable children live longer: a 55-year longitudinal study of a representative sample of the Scottish nation

The associations of childhood intelligence and dependability with adult mortality were examined in 1,181 people who were representative of the Scottish nation. Participants were born in 1936 and were followed for mortality from 1968 through early 2003. Higher intelligence and greater dependability were independent, significant predictors of lower mortality: With both factors entered together, the hazard ratio (HR) was 0.80 (95% confidence interval, CI: 0.65-0.99, p= .037) per standard deviation increase in intelligence and 0.77 (95% CI: 0.63-0.94, p= .009) per standard deviation increase in dependability. Children in the lower half of the distributions for intelligence and dependability were more than twice as likely to die compared with those who scored in the top half for both these measures (HR = 2.82; 95% CI: 1.81-4.41). Studied together for the first time in a representative sample, these two psychological variables are independent life-course risk factors for mortality. It is important to discover the mechanisms by which they influence survival.     

Long-term effects of prior cocaine exposure on Morris water maze performance

Cocaine addiction is associated with long-term cognitive alterations including deficits on tests of declarative/spatial learning and memory. To determine the extent to which cocaine exposure plays a causative role in these deficits, adult male Long-Evans rats were given daily injections of cocaine (30 mg/kg/day x 14 days) or saline vehicle. Three months later, rats were trained for 6 sessions on a Morris water maze protocol adapted from Gallagher, Burwell, and Burchinal [Gallagher, M., Burwell, R., & Burchinal, M. (1993). Severity of spatial learning impairment in aging: development of a learning index for performance in the Morris water maze. Behavioral Neuroscience, 107, 618-626]. Rats given prior cocaine exposure performed similarly to controls on training trials, but searched farther from the platform location on probe trials interpolated throughout the training sessions and showed increased thigmotaxis. The results demonstrate that a regimen of cocaine exposure can impair Morris water maze performance as long as 3 months after exposure. Although the impairments were not consistent with major deficits in spatial learning and memory, they may have resulted from cocaine-induced increases in stress responsiveness and/or anxiety. Increased stress and anxiety would be expected to increase thigmotaxis as well as cause impairments in searching for the platform location, possibly through actions on ventral striatal dopamine signaling.     

Cancer-related fatigue: a systematic and meta-analytic review of non-pharmacological therapies for cancer patients

Cancer-related fatigue (CRF) is a significant clinical problem for more than 10 million adults diagnosed with cancer each year worldwide. No "gold standard" treatment presently exists for CRF. To provide a guide for future research to improve the treatment of CRF, the authors conducted the most comprehensive combined systematic and meta-analytic review of the literature to date on non-pharmacological (psychosocial and exercise) interventions to ameliorate CRF and associated symptoms (vigor/vitality) in adults with cancer, based on 119 randomized controlled trials (RCTs) and non-RCT studies. Meta-analyses conducted on 57 RCTs indicated that exercise and psychological interventions provided reductions in CRF, with no significant differences between these 2 major types of interventions considered as a whole. Specifically, multimodal exercise and walking programs, restorative approaches, supportive-expressive, and cognitive-behavioral psychosocial interventions show promising potential for ameliorating CRF. The results also suggest that vigor and vitality are distinct phenomena from CRF with regard to responsiveness to intervention. With improved methodological approaches, further research in this area may soon provide clinicians with effective strategies for reducing CRF and enhancing the lives of millions of cancer patients and survivors.     

Interference control in preschoolers: factors influencing performance on the day–night task

Two experiments investigated preschoolers' interference control in variants of the day–night task. The day–night task involves instructing children across 16 trials to say the word ‘day’ when viewing a card depicting a nighttime sky and to say ‘night’ when shown a picture of the daytime sky. The purpose of the experiments was to investigate whether the depiction on each card distracts children because it is semantically associated with the instructed response or because the depicted item cues the alternative (incorrect) response within the response set. The results in the first study (N=23, M=52.65 months) and second study (N=54, M=50.81 months) indicate that a close semantic relation between the picture and the target response does not pose substantial interference for preschoolers. In contrast, the pictured item poses a significant challenge for preschoolers when it depicts the interfering alternative in the response set. Theoretical implications of these results for the development of interference control are discussed. Copyright © 2008 John Wiley & Sons, Ltd.     

Wittgenstein and logic

In his Tractatus Logico-Philosophicus Ludwig Wittgenstein (1889–1951) presents the concept of order in terms of a notational iteration that is completely logical but not part of logic. Logic for him is not the foundation of mathematical concepts but rather a purely formal way of reflecting the world that at the minimum adds absolutely no content. Order for him is not based on the concepts of logic but is instead revealed through an ideal notational series. He states that logic is “transcendental”. As such it requires an ideal that his philosophical method eventually forces him to reject. I argue that Wittgenstein’s philosophy is more dialectical than transcendental.     

MMPI supplemental scale performance of Mexican Americans and level of acculturation

Mexican American and Anglo American's performance on the Wiggins Content Scales, Harris-Lingoes subscales, and Serkownek subscales was assessed in a college student population. Level of acculturation (Mexican vs. Anglo orientation), age, and social class were statistically controlled. The results showed statistically significant differences between means of Anglo and Mexican Americans on most of the supplemental scales assessed. These differences were more numerous before scale validity criteria were applied. The number of statistically significant differences were further reduced when level of acculturation and age were statistically controlled. The results showed that level of acculturation is a highly important variable which moderates interpretation of the MMPI scale elevations we measured. Acculturation far outweighed the influence of the well established MMPI moderator variables of age and social class.     

Teenage pregnancy: family syndrome?

A short term, longitudinal study was conducted in order to explore selected psychosocial characteristics of fourteen teenagers aged sixteen years or younger who became mothers, the subsequent interaction of the mother-infant dyads, and the development and attachment of their infants at twelve months. The sample was matched for socioeconomic and marital status, intellectual ability and ethnicity with non-pregnant teenagers and pregnant women twenty years or older. The subjects were given a psychological and social history test battery. The groups did not differ significantly on the personality tests. The pregnant women reported a significantly poorer daughter-father relationship than the nonpregnant controls. In a high proportion of cases it was found that their fathers were absent or ineffectual and the homes mother-ridden. The interview data suggest that a large number of the pregnancies were psychologically motivated.