Chicago Urban Resiliency Building (CURB): An Internet-Based Depression-Prevention Intervention for Urban African-American and Latino Adolescents

Early preventive interventions for depressive disorders in racial/ethnic minorities may help to reduce lifetime depression outcome disparities by improving developmental trajectories and social outcomes. We describe the development process, intervention and evaluation plan for a culturally adapted, low-cost, primary care/Internet-based depression-prevention intervention (CURB, Chicago Urban Resiliency Building). CURB is culturally adapted for socio-economically disadvantaged African-American and Latino adolescents according to the PEN-3 model of health promotion programs (Airhihenbuwa in Health and culture: beyond the Western paradigm, Sage Publishers, Thousand Oaks, 1995). Based on the idea that health behavior is rooted in culture, the PEN-3 model contains three interdependent dimensions that influence health beliefs and behaviors. Within each dimension are factors (using the acronym PEN) that must be considered about the target culture. Application of the PEN-3 model occurred in 3 phases. In each phase, a dimension of the model was explored and subsequent changes were made to the intervention so as to be more culturally suitable. In the CURB clinical trial, adolescents ages 13–17 will be recruited from wait-lists for mental health services at community health care provider organizations and screened for risk of future depressive disorder in the primary care sites. Adolescents screening positive for persistent depressed mood will be randomly assigned to either the CURB intervention group or the wait-list control group. The study aims are to determine if participants in the CURB intervention group will have lower levels of depressive symptoms and/or a lower cumulative incidence of depressive episodes.     

Associations amongst disease severity,religious coping and depression in a cohort of Jamaicans with sickle-cell disease

The purpose of this study was to investigate the relationship between disease severity (sickle-cell type and hospital, emergency room and clinic emergency visits (CEU)), religious coping (positive and negative) and depression. This was accomplished through secondary analysis of a data set based on a Comprehensive Sickle Cell Standardized Questionnaire compiled by a multidisciplinary team of professionals from Duke University Medical Centre, and administered to persons with sickle-cell disease being treated at the Sickle Cell Unit on the University of the West Indies Campus between November 2008 and January 2009. Disease severity was not a good predictor of depression within the population. On the other hand, depression was found to correlate with positive and negative religious coping, such that increases in the former were associated with decreases in depression scores; while the reverse was noted for the latter (negative religious coping). The results shed light on issues that could possibly impact the treatment plan for such individuals.     

Verified Hormone Therapy Improves Episodic Memory Performance in Healthy Postmenopausal Women

ABSTRACT

Studies of hormone therapy (HT) and cognition have yielded conflicting results. The aim of this observational study was to examine the effect of estradiol, via serum verified HT (estradiol, estriol, progesterone) and endogenous estradiol, on 108 healthy postmenopausal women's cognitive performance. The results demonstrated that the 43 HT-users performed at a significantly higher level than non-users on episodic memory tasks and on a verbal fluency task, whereas HT-users and non-users did not differ on tasks assessing semantic memory and spatial visualization. In addition, there was a positive relationship between serum estradiol level and episodic memory performance, indicating that postmenopausal HT is associated with enhanced episodic memory and verbal fluency, independent of age and education. These observational results suggest that HT use may be sufficient to exert small, yet positive effects on female sensitive cognitive tasks. Hormone therapy compliance and formulation is discussed as confounding factors in previous research.     

Psychometrics of Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT) scores

A sample of 183 medical students completed the Mayer-Salovey-Caruso Emotional Intelligence Test (MSCEIT V2.0). Scores on the test were examined for evidence of reliability and factorial validity. Although Cronbach's alpha for the total scores was adequate (.79), many of the scales had low internal consistency (scale alphas ranged from .34 to .77; median = .48). Previous factor analyses of the MSCEIT are critiqued and the rationale for the current analysis is presented. Both confirmatory and exploratory factor analyses of the MSCEIT item parcels are reported. Pictures and faces items formed separate factors rather than loading on a Perception factor. Emotional Management appeared as a factor, but items from Blends and Facilitation failed to load consistently on any factor, rendering factors for Emotional Understanding and Emotional Facilitation problematic.     

The initial stage of visual selection is controlled by top-down task set: new ERP evidence

Salient visual singleton stimuli produce spatial cueing effects indicative of attentional capture only when they match current task sets, suggesting that capture is subject to top-down control. However, such task-set contingent capture effects could be associated with the top-down controlled disengagement of attention from non-matching stimuli that follows their initial bottom-up salience-driven selection. Using the N2pc component as an event-related potential marker of attentional capture, we demonstrate that top-down task set already controls the initial rapid selection of salient visual singleton stimuli prior to any subsequent attentional disengagement. These findings provide new evidence for the primacy of top-down control over bottom-up salience in attentional capture.     

Primed interference: the cognitive and behavioral costs of an incongruity between chronic and primed motivational orientations

Research has shown that temporarily primed motivational orientations have essentially the same effects on how people pursue their goals as their chronic orientations. This article shows that, despite the interchangeability of temporary and chronic motivations, primed motivational orientations that are incongruent with chronic orientations create interference, requiring the deployment of cognitive resources and thus undermining performance on subsequent tasks that rely on these resources. Across 6 studies, we primed motivational orientations that were either congruent or incongruent with participants' chronic orientations and then assessed their performance on subsequent tasks that required cognitive resources. Consistent with the primed interference hypothesis, we found that incongruity between temporary and chronic motivational orientations undermined participants' (a) inhibition of incorrect but highly accessible responses, (b) mental arithmetic, (c) analytical reasoning, and (d) resistance to temptation. These results--which were observed following the activation of motivations for promotion or prevention (Studies 1-2 and 5-6), high or low need for belonging (Study 3), and high or low power orientations (Study 4)--illustrate the broad implications of holding incongruent chronic and primed orientations.     

Stress-induced facilitation of host response to bacterial challenge in F344 rats is dependent on extracellular heat shock protein 72 and independent of alpha beta T cells

Activation of the in vivo stress response can facilitate antibacterial host defenses. One possible mechanism for this effect is stress-induced release of heat shock protein 72 (Hsp72) into the extracellular environment. Hsp72 is a ubiquitous cellular protein that is up-regulated in response to cellular stress, and modulates various aspects of immune function including macrophage inflammatory/bactericidal responses and T-cell function when found in the extracellular environment. The current study tested the hypothesis that in vivo extracellular Hsp72 (eHsp72) at the site of inflammation contributes to stress-induced restricted development of bacteria, and facilitated recovery from bacteria-induced inflammation, and that this effect is independent of alpha beta (αβ) T cells. Male F344 rats were exposed to either inescapable electrical tail-shocks or no stress, and subcutaneously injected with Escherichia coli (ATCC 15746). The role of eHsp72 was investigated by Hsp72-immunoneutralization at the inflammatory site. The potential contribution of T cells was examined by testing male athymic (rnu/rnu) nude rats lacking mature αβ T cells and heterozygous thymic intact control (rnu/+) rats. The results were that stressor exposure increased plasma concentrations of eHsp72 and facilitated recovery from bacterial inflammation. Immunoneutralization of eHsp72 at the inflammatory site attenuated this effect. Stressor exposure impacted bacterial inflammation and eHsp72 equally in both athymic and intact control rats. These results support the hypothesis that eHsp72 at the site of inflammation, and not αβ T cells, contributes to the effect of stressor exposure on subcutaneous bacterial inflammation.     

Attentional sensitization of unconscious visual processing: Top-down influences on masked priming

Classical theories of automaticity assume that automatic processes elicited by unconscious stimuli are autonomous and independent of higher-level cognitive influences. In contrast to these classical conceptions, we argue that automatic processing depends on attentional amplification of task-congruent processing pathways and propose an attentional sensitization model of unconscious visual processing: According to this model, unconscious visual processing is automatic in the sense that it is initiated without deliberate intention. However, unconscious visual processing is susceptible to attentional top-down control and is only elicited if the cognitive system is configured accordingly. In this article, we describe our attentional sensitization model and review recent evidence demonstrating attentional influences on subliminal priming, a prototypical example of an automatic process. We show that subliminal priming (a) depends on attentional resources, (b) is susceptible to stimulus expectations, (c) is influenced by action intentions, and (d) is modulated by task sets. These data suggest that attention enhances or attenuates unconscious visual processes in congruency with attentional task representations similar to conscious perception. We argue that seemingly paradoxical, hitherto unexplained findings regarding the automaticity of the underlying processes in many cognitive domains can be easily accommodated by our attentional sensitization model. We conclude this review with a discussion of future research questions regar-ding the nature of attentional control of unconscious visual processing.     

Fear of snakes and facial reactions: A case of rapid emotional responding

The aim of the present study was to explore how rapid emotional responses are manifested as facial electromyographic (EMG) reactions when people with explicit fear of snakes are exposed to their fear relevant stimuli. Fifty-six subjects, high or low in fear of snakes, were exposed to pictures of snakes and flowers while facial EMG activity from the corrugator supercilii and the zygomatic major muscle regions was recorded. Measures of autonomic activity and ratings of the stimuli were also collected. Pictures of snakes evoked a rapid corrugator supercilii muscle reaction which was larger in the High fear group as early as 500ms after stimulus onset. The High fear group also rated snakes as more unpleasant and displayed larger skin conductance responses (SCRs) and increased heart rate (HR) when exposed to snakes. Pictures of flowers tended to evoke increased zygomatic major muscle activity which did not differ among the groups. The present results demonstrate that the facial EMG technique is sensitive enough to detect rapidly evoked negative emotional reactions. The results support the hypothesis that people high in fear of snakes are disposed to react very rapidly with a negative emotional response to their fear relevant stimuli.     

Having shaved a kiwi fruit: Memory of unfamiliar subject-performed actions

Summary In an experiment with young and elderly adults, memory of unfamiliar actions performed by the subjects was compared with memory of actions low and high in familiarity, in order further to assess the role of a knowledge base as regards memory material encoded by enacting. Memory of similar actions encoded verbally was also assessed. The findings showed that the type of encoding, as well as familiarity, determined free-recall memory performance. The highest free-recall scores were found for familiar actions encoded by performance, in both an immediate and a delayed free-recall test. Recognition memory was also enhanced by enacting, whereas the influence of familiarity with an item upon recognition performance was limited to actions encoded verbally. The role of familiarity in recognition performance of actions encoded verbally was reversed compared with that in free recall, in that recognition of unfamiliar actions was most effective. Moreover, age-related memory deficits were found in this study. Elderly adults showed a consistently lower level of performance than younger subjects in both types of free-recall test and in the recognition test. This effect of age was found regardless of the type of encoding, demonstrating that age-related memory differences are not compensated by motor encoding. The age effect was also found regardless of familiarity with the items, and was most significant for unfamiliar actions. This demonstrates that elderly adults have particular difficulty in processing unfamiliar memory material.The experiment was conducted as part of the fulfillment of the requirements for obtaining the diploma degree of Maria Schumacher. Portions of this paper were presented at the 32nd Tagung experimentell arbeitender Psychologen, Regensburg, April 1990.