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61.
Buckle S 《Theoretical medicine and bioethics》2005,26(3):175-194
The paper begins by situating Singer within the British meta-ethical tradition. It sets out the main steps in his argument for utilitarianism as the ‘default setting’ of ethical thought. It argues that Singer’s argument depends on a hierarchy of reasons, such that the ethical viewpoint is understood to be an adaptation – an extension – of a fundamental self-interest. It concludes that the argument fails because it is impossible to get from this starting-point in self-interest to his conception of the ethical point of view. The fundamental problem is its mixing the immiscible: the Humean subordination of reason to interest with the Kantian conception of reason as universal and authoritative. 相似文献
62.
This study explored the effects of ageing on working memory by means of the directed forgetting procedure designed by Reed (1970). Memory for a letter trigram was compared in conditions where it was either presented alone (single-item), or followed by a second trigram to be recalled (interference), or followed by a second trigram to be forgotten (directed forgetting). The results clearly indicated that elderly participants inhibited the no-longer-relevant information less efficiently (recall in the single-item condition - recall in the directed forgetting condition), as predicted by the model of Hasher and Zacks (1988). However, the results also demonstrated that sensitivity to interference (recall in the single-item condition - recall in the interference condition) increased in the condition in which no inhibition was directly required. 相似文献
63.
Bellissimo MI Kouzmine I Ferro MM de Oliveira BH Canteras NS Da Cunha C 《Neurobiology of learning and memory》2004,82(2):150-158
Adult male Wistar rats with a substantia nigra pars compacta (SNc) lesion induced by intranigral administration of 1 micromol 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) were used as a model of early phase Parkinson's disease (PD). This lesion caused a partial depletion of striatal dopamine (DA). The animals were submitted to a spatial working memory version of the water maze task in which they had to find a hidden (submersed) platform using online-maintained information that the platform remains in the same place during four consecutive trials, but that it is moved to another place every training day. Left, but not right SNc-lesioned rats were impaired in finding the platform in the second trial. This result suggests that the left SNc plays a key role in spatial working memory. Control experiments ruled out the possibility that motor impairment, sensory neglect, and/or impairment in the mental representation of the contralateral spatial environment had affected performance of the SNc-lesioned rats. 相似文献
64.
In three experiments, we examined comprehension judgments made after a piece of text had been read. We propose that such metacognitive judgments are based on the content of working memory at the exact moment of assessment. Generally speaking, this working metacognition hypothesis is in agreement with Koriat's cue utilization approach, which implies that different elements of information will be available (and used) depending on the moment at which a judgment is made. More specifically, our hypothesis focuses on the management of working memory during reading as a cause for cue (un)availability. In support of these views, the results of Experiment 1 showed that a cohesion manipulation affecting the comprehension of specific paragraphs influences judgments only on these paragraphs, and not on judgments on the whole text. In Experiment 2, we showed that an interfering task that takes place just before this paragraph judgment is made wipes out this cohesion effect. Experiment 3 showed, on the other hand, that the whole-text judgment may, nevertheless, be affected by text cohesion, provided that the readers keep an access to the text when the judgment is made. These results support the idea that working memory management makes different cues available for metacognitive ratings at different delays. 相似文献
65.
Calvin S Milliex L Coyle T Temprado JJ 《Journal of experimental psychology. Human perception and performance》2004,30(6):1032-1042
The recruitment of an additional biomechanical degree of freedom in a unimanual rhythmic task was explored. Subjects were asked to synchronize adduction or abduction of their right index finger with a metronome, the frequency of which was increased systematically. In addition, haptic contact on or off the metronome beat was provided. Results showed that the pattern exhibiting the highest intrinsic stability recruited the vertical plane more than did the less stable one. Moreover, presence and location of haptic contact modulated coordination stability and therefore induced changes in the recruitment of the vertical plane. Thus, a trade-off was shown between coordination stability on the horizontal plane and recruitment of the vertical one. These findings suggest that recruitment of degrees of freedom is governed by general principles of coordination dynamics. 相似文献
66.
Listeners cannot recognize highly reduced word forms in isolation, but they can do so when these forms are presented in context (Ernestus, Baayen, & Schreuder, 2002). This suggests that not all possible surface forms of words have equal status in the mental lexicon. The present study shows that the reduced forms are linked to the canonical representations in the mental lexicon, and that these latter representations induce reconstruction processes. Listeners restore suffixes that are partly or completely missing in reduced word forms. A series of phoneme-monitoring experiments reveals the nature of this restoration: the basis for suffix restoration is mainly phonological in nature, but orthography has an influence as well. 相似文献
67.
Participants switched frequently between high/low and odd/even classification of a digit. The interval between a task cue and the next digit varied between blocks. In Experiment 1, the task switched predictably every two, four, or eight trials. In Experiment 2, switching predictably every four trials was compared with random switching. With predictable switching, the cost was limited to the first trial of a run. Random switching produced a more gradual approach to asymptotic performance. After one performance, control processes attenuate the resulting change in task-set bias if a further switch is likely, but this strategic modulation is soon overwhelmed by task-set priming through further performances. Preparation reduced switch costs but not interference from the irrelevant attribute: Control of interference appears to be reactive, not proactive. Switch costs did not increase with run length, suggesting that retrieval of the task set last associated with the stimulus did not contribute to switch costs. 相似文献
68.
Nourrit D Delignières D Caillou N Deschamps T Lauriot B 《Journal of motor behavior》2003,35(2):151-170
The qualitative behavioral reorganizations that occurred during the acquisition of a complex motor skill were examined. Five novice participants practiced for 39 sessions of ten 1-min trials on a modified version of the ski-simulator. Analyses focused on the motion of the apparatus platform, modeled as a self-sustained oscillator. At the beginning of the experiment, all participants adopted a behavior that could be modeled with a highly nonlinear stiffness function and a Rayleigh damping function. The behavior in the final part of the experiment was captured by a qualitatively different model, with a linear stiffness function and a van der Pol damping behavior. The transition from the initial to the final model was gradual and was marked in most cases by an abrupt increase of oscillation frequency. During the transition stage, the 2 damping behaviors seemed alternately exploited within each trial. The results are discussed in the framework of the dynamical systems approach to motor coordination and learning, considering motor skill acquisition as a phase transition. 相似文献
69.
Modulation of tremor amplitude during deep brain stimulation at different frequencies 总被引:2,自引:0,他引:2
Rest tremor was quantified in the index finger tip of 16 patients with Parkinson's disease (PD) receiving deep brain stimulation (DBS) of the ventro-intermediate nucleus (Vim) of the thalamus, the subthalamic nucleus (STN), or the internal part of the globus pallidus (GPi) while being off L-dopa for 12h. Clinically, without DBS, tremor amplitude varied from absent to high. Tremor was recorded continuously for about 5 min under three conditions of DBS repeated twice, namely, effective frequency (E), ineffective frequency (I), and no DBS (O). No changes in tremor were observed across conditions in subjects with little or no tremor. However, in subjects with moderate to large amplitude tremor, DBS decreased tremor amplitude to near normal values within a few seconds. Generally, transitions were progressive and occurred with a varying time delay. Occasionally, tremor escaped from control regardless of the stimulation condition considered. In some cases tremor amplitude in one condition appeared to depend on the preceding condition. Finally, the results were reproducible on two consecutive days. We conclude that tremor control with DBS follows specific dynamical rules, which must be compatible with the hypotheses proposed regarding the underlying mechanisms of DBS. 相似文献
70.
The aim of the present paper was to investigate how the kinematics of a hand reaching toward a visual target would be influenced by haptic and proprioceptive input from an unseen distractor actively grasped in the other, nonreaching hand. The main results were that the amplitude of maximum grip aperture was smaller and the time to maximum grip aperture was earlier when the distractor was smaller than the target. The interference effect from the distractor was similar for both hands as they reached. Furthermore, results from a vibrating-distractor condition for passive tactile input revealed that the interference effects were evident only when the distractor was actively grasped. We suggest that neural processing of proprioceptive and tactile information relevant to distractor size produced the observed interference effects. We also emphasize the importance of active manipulation of the distractor stimulus in eliciting such interference effects. 相似文献