Genetic Counseling Considerations in the Evaluation of Families for Lynch Syndrome��A Review

Lynch syndrome is the most common hereditary colorectal cancer syndrome and the most common cause of hereditary endometrial cancer. Identifying and evaluating families for Lynch syndrome is increasing in complexity due to the recognition that: family history-based clinical criteria lack sensitivity and specificity; genetic testing for Lynch syndrome continues to evolve as understanding of the molecular mechanisms underlying it evolves; and the Lynch syndrome phenotype encompasses multiple organ systems and demonstrates overlap with other hereditary cancer syndromes. This document is a summary of considerations when evaluating individuals and families for Lynch syndrome, including information on cancer risks, diagnostic criteria, tumor and genetic testing strategies, and the management of individuals with this condition.     

Assessing anti-fat bias in preschoolers: a comparison of a computer generated line-drawn figure array and photographic figure array

This study examined differences in preschoolers' ratings of anti-fat bias and identification of current body size depending on the realism of the figure array used: computer generated line-drawn or photographic. Children reported strong anti-fat bias with both arrays. However, less extreme bias was elicited with the photographic figure array. In addition, children were inaccurate reporters of their current body size when both figure arrays were used. However, children were consistent in their selection of figures that were thinner than their actual body size. Children's consistent selection of thinner figures as representative of their current body size may be an additional indicator of anti-fat bias. Overall, these results suggest that some of the anti-fat bias observed in preschoolers is attributable to less realistic figure arrays. Therefore, photographic figure arrays are proposed as a better measurement tool in the assessment of anti-fat bias in preschoolers.     

Intervening with Military Couples Struggling with Issues of Sexual Infidelity

Both the prevalence and adverse impact of infidelity argue for the importance of disseminating evidence-based interventions for couples struggling with this highly disruptive event. We describe an integrative approach for promoting recovery from infidelity drawing on empirically supported treatments for couple distress as well as empirical literature regarding recovery from interpersonal trauma and recovery from relationship injuries. We then describe a structured 8 session adaptation of this protocol tailored to military couples struggling with issues of infidelity. Reaching these high-risk couples requires extending both the availability and efficacy of services delivered by professionals within the military from diverse disciplines. We present initial findings indicating that US Army chaplains receiving training in this structured protocol not only can learn information regarding the conceptual underpinnings and specific interventions comprising this treatment, but also can apply it appropriately in analog clinical situations. We conclude with suggestions for extending dissemination efforts to reduce acute adverse consequences experienced by service members and their partners experiencing infidelity.     

The effect of humorous instructional materials on interest in a math task

Two studies tested the effect of humor, embedded in learning materials, on task interest. College student participants (N _{Study 1} = 359, N _{Study 2} = 172) learned a new math technique with the presence or absence of humor in the learning program and/or test instructions. Individual interest in math was measured initially and also tested as a factor. The results showed that the effect of humor in the learning program depended on individual interest in math. Humor raised task interest for those with low individual interest in math but slightly lowered task interest for those with high individual interest in math. Mediating variables of this effect were tested across both studies. Although the mediating variables showed inconsistency, humor may affect task interest through affective responses immediately following the instruction, rather than in subsequent interaction with the task.     

Foundational numerical capacities and the origins of dyscalculia

One important cause of very low attainment in arithmetic (dyscalculia) seems to be a core deficit in an inherited foundational capacity for numbers. According to one set of hypotheses, arithmetic ability is built on an inherited system responsible for representing approximate numerosity. One account holds that this is supported by a system for representing exactly a small number (less than or equal to four4) of individual objects. In these approaches, the core deficit in dyscalculia lies in either of these systems. An alternative proposal holds that the deficit lies in an inherited system for sets of objects and operations on them (numerosity coding) on which arithmetic is built. I argue that a deficit in numerosity coding, not in the approximate number system or the small number system, is responsible for dyscalculia. Nevertheless, critical tests should involve both longitudinal studies and intervention, and these have yet to be carried out.