Effects of dehydroepiandrosterone sulfate and progesterone on spatial learning and memory in young and aged mice

Young (2-4 months) and aged (14-16 months) male Swiss-Webster albino mice (n = 7 per group) were subcutaneously injected with 20 mg/kg/day dehydroepiandrosterone sulfate (DHEAS), progesterone (P), DHEAS + P, or vehicle control and trained over a 5-day period in a Morris water maze. The subjects were tested 48 hr after training for memory recall as measured by latencies to locate the hidden platform, and trunk blood was collected immediately thereafter. As expected, latency to platform decreased for all groups over the 6 testing days, with aged mice taking longer to reach platform than did young mice. However, results did not support the hypotheses that DHEAS-treated mice would exhibit shorter latencies and that P-treated mice would show longer latencies to platform in comparison with age-matched controls. These results raise doubts about the effectiveness of commercially available supplements claiming to promote enhanced memory in humans.     

"I no longer believe": did Freud abandon the seduction theory?

Recent accounts of the seduction theory and the question of its abandonment have emphasized the continuity of Freud's work before and after the seduction theory, claiming that Freud did not abandon his concern with the event of seduction but rather came to appreciate that an understanding of fantasy was also essential. This claim is challenged. It is shown that Freud did abandon the passionate concerns of his seduction theory for the most part; that he left behind his early interest in reconstructing unconscious infantile incest and focused instead on later, conscious seduction; that he at times clearly reduced apparent paternal incest to fantasy; that he turned away from the phenomenology of incest he had begun to develop; and that he theoretically nullified the value of the difference between real and fantasied seduction. It is also shown that, contrary to a persistent concern in psychoanalytic history, attention to actual seduction need not detract from the essential psychoanalytic concern with fantasy and infantile sexuality. Thinking about incest specifically illuminates the capacity for fantasizing, the core of the Freudian psyche. In this way the intuition of the seduction theory that there is something of distinctive psychoanalytic significance about incest finds support.     

Cognitive Control in Children with ADHD-C: How efficient are they?

The literature on children with attention deficit/hyperactivity disorder, combined type (ADHD-C), is currently inconclusive as to the nature of deficits in two forms of cognitive control — interference control and response selection (Nigg, 2006 Nigg, J. T. 2006. What Causes ADHD? Understanding what goes wrong and why, New York: The Guildford Press.  [Google Scholar]). This paper examined the performance of children with ADHD-C on interference control and response selection conflict tasks that required both speed and accuracy. The data was analyzed utilizing a new efficiency method to more effectively analyze overall responses. Both interference control and response selection conditions were combined within tasks allowing for a closer comparison of how children with ADHD-C perform on these specific types of cognitive control. Computerized tasks were administered to 62 boys, ages 7 to 12 (31 controls, 31 ADHD-C). Results revealed deficits in efficient performance for children with ADHD-C on interference control tasks and response selection tasks hypothesized to involve high cognitive control demand. These results highlight the utility of analyzing efficiency data to identify deficits in performance for children with ADHD-C and to foster an increased understanding of cognitive control functioning in this clinical population.     

Post-irradiation annealing behaviour of oxide dispersion strengthened Fe-Cr alloys studied by nanoindentation

ABSTRACT

To study the nature of irradiation-induced nanofeatures in oxide dispersion strengthened (ODS) Fe-Cr alloys, post-irradiation isochronal thermal annealing up to 600°C was performed for ODS Fe-9%Cr and Fe-14%Cr alloys ion-irradiated at 300°C and 500°C. Nanoindentation indicated hardening for all as-irradiated alloys and complete hardness recovery upon post-irradiation annealing. Cross-sectional TEM indicated an irradiation-induced defect band near peak damage mainly consisting of dislocation loops. Candidate mechanisms of recovery were critically evaluated. Shrinkage of loops via capture of thermal vacancies was found to correctly reflect the annealing behaviour of ODS Fe-9Cr irradiated at 300°C.     

The Romance of Learning from Disagreement. The Effect of Cohesiveness and Disagreement on Knowledge Sharing Behavior and Individual Performance Within Teams

Purpose  

The purpose of this study was to explore the effects of disagreement and cohesiveness on knowledge sharing in teams, and on the performance of individual team members.     

From negative to positive and back again: Polarized affective and relational experience in borderline personality disorder

A core feature of borderline personality disorder (BPD) is the tendency to evaluate one's experience with extreme polarity (i.e., feeling all good or all bad; Beck, Freeman, & Davis, 2004; Kernberg, 1975; Linehan, 1993). In this investigation, we examined the polarity of within-person reports of experience in individuals with BPD and healthy adults over the course of a 21-day, experience-sampling diary. We applied multilevel modeling techniques (Rafaeli, Rogers, & Ravelle, 2007) to capture the within-person covariance of momentary reports of negative and positive features of experience, either affective or relational. Our data indicated significantly greater polarity in reports of affective and relational experiences in BPD that increased during heightened interpersonal stress. We also examined the association of affective and relational polarity to reports of impulsive behaviors (e.g., self-injury, substance use, etc.) and found evidence that increased polarity in reports of affective (in low-stress contexts) and relational experiences (in high-stress contexts) predicted increased rate of reports of impulsive behaviors. Together, these data present strong evidence for the role of polarized experiences in BPD, and have implications for the treatment of individuals with this disorder. (PsycINFO Database Record (c) 2012 APA, all rights reserved).     

What Information Do Cancer Genetic Counselees Prioritize?

This study explored the informational needs of individuals attending genetic counseling for hereditary cancer, using a free-choice and a forced choice method. Prior to the consultation the informational needs of 334 counselees from Sweden and Norway were assessed by the QUOTE-gene (ca) questionnaire and by a study specific forced choice method, using Q-methodology. Questionnaire responses indicated that counselees' major concerns pertained to the need to be taken seriously, to be provided with sufficient risk estimation and medical/genetic information and to be involved in the decision making process. Furthermore, prior to counseling, counselees noted that the counselors' consideration and skillfulness were also extremely important. Analysis of the Q-sorting results revealed that counselees' needs could be assigned to one of five groups: the "need for facts; caring communication and medical information; information and support in communicating the genetic information to others; practical care and practical/medical information". Particularly noteworthy, counselees with varying backgrounds characteristics prioritized different needs. Cancer genetic counselees probably have different needs due to their medical and demographic background when attending genetic counseling. Addressing counselees' specific concerns more sufficiently and thereby increasing the overall effectiveness of the counseling session requires increased insight into individual needs, by for instance, utilizing screening methods such as QUOTE-gene (ca) prior to the counseling session.     

Cross-sectional and longitudinal confirmatory factor models for the german test anxiety inventory: A construct validation

Construct validity of the German Test Anxiety Inventory (TAI-G) was tested in two respects. Firstly, the purported four-dimensional structure of the TAI-G (comprising subscales Emotionality, Worry, Interference, and Lack of Confidence) as well as relations of the test anxiety dimensions to self-efficacy were tested. Secondly, the trait conception of the TAI-G was tested within the framework of Latent State-Trait theory. The TAI-G was given to a student sample (N=302) on three occasions with a time interval of 2 weeks along with a study-specific self-efficacy scale on occasion 1. Dimensionality assumptions as well as relations with self-efficacy were tested using cross-sectional second-order confirmatory factor analysis. The trait conception was tested separately for TAI-G subscales by specifying longitudinal confirmatory factor models (Latent State-Trait models) and by calculating variance proportions of manifest variables (Latent State-Trait coefficients) referring to different sources of systematic variance (person, situation, and method) based on parameter estimates of the models. Results were supportive of both the purported four-dimensional structure and hypothesized relationships to self-efficacy (i.e., acceptable model fit) as well as of the trait conception of test anxiety (i.e., acceptable model fit and high proportion of variance due to person component). Implications for further validation studies were discussed.     

Influence of Attachment Style on Major Psychological Capacities to Lead

Addressing psychological literature's deficiency in research on the early development of leaders in everyday life (e.g., leaders in the workplace, leaders in social settings, leaders in organizational settings), this study assumed that central psychological capacities required for such leaders can be predicted and explained by J. Bowlby's (1969) Bowlby, J. 1969. Attachment and loss: Vol. 1. Attachment New York : Basic Books. [Google Scholar] attachment theory concerning developmental processes in infancy. The authors administered a series of questionnaires to 402 participants. The authors analyzed data by using structural equation modeling. Findings indicate a potential-to-lead construct that forms in infancy. The results fully supported the authors’ main arguments: that secure attachment style influences the potential to lead and that this capacity is essential for leadership as measured by leadership ranking.