Determinism and locality in quantum mechanics

In current philosophical debate Bell's theorem is often refered to as a proof of the impossibility of determinism in nature. It is argued here that this conclusion is wrong. The main consequence of the theorem is the non-local character of quantum theory itself and it is shown how this quality leads to a contradiction with the theory of relativity. If hidden variable theories are impossible, it is so because no empirically founded interpretation at all can be compatible with both quantum mechanics and relativity.     

Religious Perspectives on the Use of Psychopharmaceuticals as an Enhancement Technology

The use of psychopharmaceuticals as an enhancement technology has been the focus of attention in the bioethics literature. However, there has been little examination of the challenges that this practice creates for religious traditions that place importance on questions of being, authenticity, and identity. We asked expert commentators from six major world religions to consider the issues raised by psychopharmaceuticals as an enhancement technology. These commentaries reveal that in assessing the appropriate place of medical therapies, religious traditions, like secular perspectives, rely upon ideas about health and disease and about normal human behavior. But unlike secular perspectives, faith traditions explicitly concern themselves with ways in which medicine should or should not be used to live a “good life”.     

The involuntary nature of music-evoked autobiographical memories in Alzheimer's disease

The main objective of this paper was to examine the involuntary nature of music-evoked autobiographical memories. For this purpose, young adults, older adults, and patients with a clinical diagnosis of probable Alzheimer's disease (AD) were asked to remember autobiographical events in two conditions: after being exposed to their own chosen music, and in silence. Compared to memories evoked in silence, memories evoked in the "Music" condition were found to be more specific, accompanied by more emotional content and impact on mood, and retrieved faster. In addition, these memories engaged less executive processes. Thus, with all these characteristics and the fact that they are activated by a perceptual cue (i.e., music), music-evoked autobiographic memories have all the features to be considered as involuntary memories. Our paper reveals several characteristics of music-evoked autobiographical memories in AD patients and offers a theoretical background for this phenomenon.     

When deception influences memory: the implication of theory of mind

When deceiving, one should remember to whom a falsified story was previously told; otherwise he or she may include inconsistencies, and the deception will probably be discovered. Bearing this in mind, we investigated the potential relationship between deception and the ability to remember to whom a piece of information was previously told (i.e., destination memory). Forty-one adults were given a destination memory task in which they had to decide to whom proverbs had previously been told. They were also given a questionnaire about deception (e.g., “I sometimes tell lies if I have to) and a cognitive theory of mind task in which they had to predict the behaviour of protagonists who hold a mistaken belief about the state of the world. Results showed a positive correlation between deception and destination memory (p <?.001), a relationship that was further mediated by cognitive theory of mind ability (p?<?.01). Deception requires monitoring and inferring what targets know, suspect, and believe. This monitoring ability (i.e., cognitive theory of mind) results in better processing of the target and consequently better destination memory. By showing the involvement of deception and theory of mind in destination memory, our findings emphasize the memory variations in social and interpersonal interactions.     

Affective and cognitive attitudes, uncertainty avoidance and intention to obtain genetic testing: an extension of the Theory of Planned Behaviour

To ensure successful implementation of genetic screening and counselling according to patients best interests, the attitudes and motives of the public are important to consider. The aim of this study was to apply a theoretical framework in order to investigate which individual and disease characteristics might facilitate the uptake of genetic testing. A questionnaire using an extended version of the Theory of Planned Behaviour was developed to assess the predictive value of affective and cognitive expected outcomes, subjective norms, perceived control and uncertainty avoidance on the intention to undergo genetic testing. In addition to these individual characteristics, the predictive power of two disease characteristics was investigated by systematically varying the diseases fatality and penetrance (i.e. the probability of getting ill in case one is a mutation carrier). This resulted in four versions of the questionnaire which was mailed to a random sample of 2400 Norwegians. Results showed genetic test interest to be quite high, and to vary depending on the characteristics of the disease, with participants preferring tests for highly penetrant diseases. The most important individual predictor was uncertainty avoidance.     

Expanding the Limits of Bibliotherapy for Panic Disorder: Randomized Trial of Self-Help Without Support but With a Clear Deadline

Cognitive behavioral bibliotherapy for panic disorder has been found to be less effective without therapist support. In this study, participants were randomized to either unassisted bibliotherapy (n = 20) with a scheduled follow-up telephone interview or to a waiting list control group (n = 19). Following a structured psychiatric interview, participants in the treatment group were sent a self-help book consisting of 10 chapters based on cognitive behavioral strategies for the treatment of panic disorder. No therapist contact of any kind was provided during the treatment phase, which lasted for 10 weeks. Results showed that the treatment group had, in comparison to the control group, improved on all outcome measures at posttreatment and at 3-month follow-up. The tentative conclusion drawn from these results is that pure bibliotherapy with a clear deadline can be effective for people suffering from panic disorder with or without agoraphobia.     

Comparison of chemosensory, auditory and visual event-related potential amplitudes

To enhance understanding of neuropsychological processing underlying chemosensory event-related potentials (CSERPs), the objective of the present study was to compare CSERPs with auditory (AERPs) and visual event-related potentials (VERPs), and to approach the question of similarities in neuropsychological processing by means of correlation and cluster analyses. A multisensory ERP protocol was used, in which olfactory/chemosomatosensory (pyridine), auditory (1000-Hz tone) and visual (white circle) stimuli were presented in a pseudo-randomized sequence to 18 young, healthy adults. The results show (1) a morphological relation between P2 and P3 components that is different for the chemosensory than for the auditory and visual modalities, (2) a relatively weak association between the chemosensory and auditory/visual modalities for P3 in terms of both correlation and cluster, and (3) a P2/P3 cluster for the chemosensory but not auditory or visual modality. This supports the claim that the chemosensory P2 and P3 components reflect similar neuropsychological processes.     

Cancer Genetic Counselees’ Self-Reported Psychological Distress, Changes in Life, and Adherence to Recommended Surveillance Programs 3–7 Years Post Counseling

The aim of the present cross-sectional study was to investigate psychological distress, changes in life, adherence to surveillance programs and satisfaction with cancer genetic counseling based on Swedish participants’ self-reported data. A total of 218 probands (72% response rate) affected by breast, breast/ovarian or colorectal cancer and/or a family history of cancer were surveyed 3–7 years after receiving cancer genetic counseling. Participants reported a relatively high level of anxiety and a low level of depression. Probands affected by colorectal cancer reported a higher level of depression than did non-affected individuals with a family history of colorectal cancer. Overall, the participants reported moderate changes in family relations, priorities and appreciation of daily life activities. The majority of at-risk probands reportedly adhered to recommended surveillance programs. The mean level of satisfaction with cancer genetic counseling was high. About half of the participants would have accepted additional counseling sessions, contact with a psychologist or further help concerning informing family members. The present results indicate no adverse effects of genetic counseling, but they do suggest that typical counseling procedures could be improved by provision of additional psychosocial support.     

The Limits of Medical Practice

Theoretical Medicine and Bioethics - Should medicine be defined as the enterprise in charge of the health problems of society? If so, then any problem (individual, public, social or political) that...     

Directed forgetting of autobiographical memory in mild Alzheimer's disease

Using the autobiographical directed forgetting method (Barnier et al., 2007), the present paper addressed the intentional inhibitory processes of episodic and semantic autobiographical memory in Alzheimer's disease (AD). Mild AD patients and healthy elderly people were instructed to either forget or to continue remembering previously generated autobiographical events. In a later recall test they were asked to reconstruct the early-generated memories regardless of the forget/remember instruction. Autobiographical reconstruction was further distributed into episodic and semantic memories. Results showed no forget instruction effect on episodic or semantic autobiographical recall with AD patients, whereas healthy elderly people were able to inhibit only episodic autobiographical memories. The findings suggest an impairment of the intentional inhibitory processes in autobiographical memory with AD and a relative preservation of these mechanisms with normal ageing. They also demonstrate an earlier decline in the intentional inhibitory processes compared to the autobiographical deterioration in AD.