Toward a Model Informed Consent Process for BRCA1 Testing: A Qualitative Assessment of Women's Attitudes

As an initial part of a project to develop a model informed consent process for BRCA1 testing, we conducted a series of focus groups. At the groups, women initially expressed great interest in testing, but their interest diminished after learning more. If offered testing, women would most want to learn about test accuracy, practical details of testing, and management options if the result was positive. Perceived benefits of testing included gaining information leading to risk reduction, relief of uncertainty, more responsible parenting, and assisting in research. Perceived risks included the discomfort and cost of the testing process itself, and anxiety after a positive result. The risk of possible insurance discrimination was rarely mentioned spontaneously. Many women would want their providers to make recommendations, rather than be nondirective about testing. We observed that women vary greatly in their informational and counseling needs, and suggest that the informed consent process should be individualized, taking into account a woman's perception and her preferences for how testing decisions should be made.     

Equivalence of Problems (An Attempt at an Explication of Problem)

On the one hand, Pavel Tichý has shown in his Transparent Intensional Logic (TIL) that the best way of explicating meaning of the expressions of a natural language consists in identification of meanings with abstract procedures. TIL explicates objective abstract procedures as so-called constructions. Constructions that do not contain free variables and are in a well-defined sense ´normalized´ are called concepts in TIL. On the second hand, Kolmogorov in (Mathematische Zeitschrift 35: 58–65, 1932) formulated a theory of problems, using NL expressions. He explicitly avoids presenting a definition of problems. In the present paper an attempt at such a definition (explication)—independent of but in harmony with Medvedev´s explication—is given together with the claim that every concept defines a problem. The paper treats just mathematical concepts, and so mathematical problems, and tries to show that this view makes it possible to take into account some links between conceptual systems and the ways how to replace a noneffective formulation of a problem by an effective one. To show this in concreto a wellknown Kleene’s idea from his (Introduction to metamathematics. D. van Nostrand, New York, 1952) is exemplified and explained in terms of conceptual systems so that a threatening inconsistence is avoided.     

Dissociation between location and shape in visual space

There are often large perceptual distortions of shapes lying on the ground plane, even in well-lit environments. These distortions occur under conditions for which the perception of location i saccurate. Four hypotheses are considered for reconciling these seemingly paradoxical results, after which 2 experiments are reported that lend further support to 1 of them--that perception of shapeand perception of location are sometimes dissociable. The 2 experiments show that whereas perception of location does not depend on whether viewing is monocular or binocular (when other distance cues are abundant), perception of shape becomes more veridical when viewing is binocular. This means that perception of shape is not fully constrained by the perceived locations of the vertices that define the shape.     

The logic of ability,freedom and responsibility

The aim of this paper is to offer a rigorous explication of statements ascribing ability to agents and to develop the logic of such statements. A world is said to be feasible iff it is compatible with the actual past-and-present. W is a P-world iff W is feasible and P is true in W (where P is a proposition). P is a sufficient condition for Q iff every P world is a Q world. P is a necessary condition for Q iff Q is a sufficient condition forP. Each individual property S is shown to generate a rule for an agent X. X heeds S iff X makes all his future choices in accordance with S. (Note that X may heed S and yet fail to have it). S is a P-strategy for X iff X's heeding S together with P is a necessary and sufficient condition for X to have S. (P-strategies are thus rules which X is able to implement on the proviso P).Provisional opportunity: X has the opportunity to A provided P iff there is an S such that S is a P-strategy for X and X's implementing S is a sufficient condition for X's doing A. P is etiologically complete iff for every event E which P reports P also reports an etiological ancestry of E, and P is true. Categorical opportunity: X has the opportunity to A iff there is a P such that P is etiologically complete and X has the opportunity to A provided P. For X to have the ability to A there must not only be an appropriate strategy, but X must have a command of that strategy. X steadfastly intends A iff X intends A at every future moment at which his doing A is not yet inevitable. X has a command of S w.r.t. A and P iff X's steadfastly intending A together with P is a sufficient condition for X to implement S. Provisional ability: X can A provided P iff there is an S such that S is a P-strategy for X, X's implementing S is a sufficient condition for X's doing A, and X has a command of S w.r.t. A and P. Categorical ability: X can A iff there is a P such that P is etiologically complete and X can A provided P. X is free w.r.t. to A iff X can A and X can non- A. X is free iff there is an A such that X is free w.r.t. A.     

Results of a preliminary survey of computer users in psychological laboratories

A short questionnaire was distributed to a subset of the computer users connected with the National Conference on the Use of On-Line Computers in Psychology to determine the type of computer equipment used by psychologists and the current uses of that equipment. The results of this pilot study are discussed in this paper.