Reconsolidation of a context long-term memory in the terrestrial snail requires protein synthesis

We investigated the influence of the protein synthesis blocker anisomycin on contextual memory in the terrestrial snail Helix. Prior to the training session, the behavioral responses in two contexts were similar. Two days after a session of electric shocks (5 d) in one context only, the context conditioning was observed as the significant difference of behavioral response amplitudes in two contexts. On the day following testing of context learning, a session of "reminding" was performed, immediately after which the snails were injected with anisomycin or vehicle. Testing of long-term context memory has shown that only anisomycin injections impaired the context conditioning. In control series, the snails were injected after the training session with anisomycin/saline without reminding, and no impairment of the long-term context memory was observed, while injection of anisomycin during the training session completely abolished the long-term memory. No effects of anisomycin on the short-term memory were observed. Surprisingly, injection of anisomycin after the reminding combined with reinforcing stimuli elicited no effect on the context memory. Differences between single-trial and multisession learning are discussed.     

Dissociation between location and shape in visual space

There are often large perceptual distortions of shapes lying on the ground plane, even in well-lit environments. These distortions occur under conditions for which the perception of location i saccurate. Four hypotheses are considered for reconciling these seemingly paradoxical results, after which 2 experiments are reported that lend further support to 1 of them--that perception of shapeand perception of location are sometimes dissociable. The 2 experiments show that whereas perception of location does not depend on whether viewing is monocular or binocular (when other distance cues are abundant), perception of shape becomes more veridical when viewing is binocular. This means that perception of shape is not fully constrained by the perceived locations of the vertices that define the shape.     

Two Modulatory Inputs Exert Reciprocal Reinforcing Effects on Synaptic Input of Premotor Interneurons for Withdrawal in Terrestrial Snails

A cluster of serotonergic cells in the rostral part of pedal ganglia of the terrestrial snail Helix lucorum was shown previously to participate in modulation of withdrawal behavior, and to be necessary for elaboration of aversive withdrawal conditioning in intact snails. In the present experiments local extracellular stimulation of the serotonergic cells elicited a pairing-specific increase (difference between paired and explicitly unpaired sessions was significant, P<0.01) of synaptic responses in the premotor interneurons involved in withdrawal to paired nerve stimulation. Intracellular stimulation of only one Pd4 cell from the pedal group of serotonergic neurons increased (P<0.05) synaptic responses to contingent test nerve stimulation significantly in the same premotor interneurons for 2–3 hr.     

The logic of ability,freedom and responsibility

The aim of this paper is to offer a rigorous explication of statements ascribing ability to agents and to develop the logic of such statements. A world is said to be feasible iff it is compatible with the actual past-and-present. W is a P-world iff W is feasible and P is true in W (where P is a proposition). P is a sufficient condition for Q iff every P world is a Q world. P is a necessary condition for Q iff Q is a sufficient condition forP. Each individual property S is shown to generate a rule for an agent X. X heeds S iff X makes all his future choices in accordance with S. (Note that X may heed S and yet fail to have it). S is a P-strategy for X iff X's heeding S together with P is a necessary and sufficient condition for X to have S. (P-strategies are thus rules which X is able to implement on the proviso P).Provisional opportunity: X has the opportunity to A provided P iff there is an S such that S is a P-strategy for X and X's implementing S is a sufficient condition for X's doing A. P is etiologically complete iff for every event E which P reports P also reports an etiological ancestry of E, and P is true. Categorical opportunity: X has the opportunity to A iff there is a P such that P is etiologically complete and X has the opportunity to A provided P. For X to have the ability to A there must not only be an appropriate strategy, but X must have a command of that strategy. X steadfastly intends A iff X intends A at every future moment at which his doing A is not yet inevitable. X has a command of S w.r.t. A and P iff X's steadfastly intending A together with P is a sufficient condition for X to implement S. Provisional ability: X can A provided P iff there is an S such that S is a P-strategy for X, X's implementing S is a sufficient condition for X's doing A, and X has a command of S w.r.t. A and P. Categorical ability: X can A iff there is a P such that P is etiologically complete and X can A provided P. X is free w.r.t. to A iff X can A and X can non- A. X is free iff there is an A such that X is free w.r.t. A.     

On the functional form of partial masking functions in psychoacoustics

Partial masking of pure tones is often investigated in terms of matching functions which record the intensity φ(x, n) of an unmasked tone which matches, in perceived loudness, a tone of intensity x embedded in a flat, broadband noise of intensity n. Empirically, the following property of “shift invariance” is observed to hold for these matching functions: φ(λx, λ^θn) = λφ(x, n), for any λ > 0, and some θ < 1. In the context of the model $\text{φ(x, n) = F}{}_0\text{[}\text{g}{}_0\text{(x)}\text{(h}{}_0\text{(x) + k}{}_0\text{(n))}\text{]}$ which expresses the idea that the effect of a noise mask is to control the gain of a pure tone signal in a multiplicative fashion, shift invariance proves to be an extremely powerful theoretical constraint. Specifically, we show that only two parametric families of functions (F₀, g₀, h₀, k₀) are possible candidates for interpolating empirical data. These two parametric families are given by the following expressions: $\text{φ}{}_1\text{(x, n) = A(}\text{x}{}^{\mathrm{\alpha }}\text{(x}{}^{\mathrm{\alpha \prime }}\text{+ Kn}{}^{\mathrm{<mtext>\alpha \prime </mtext><mtext>\theta </mtext>}}\text{)}\text{)}{}^{\mathrm{<mtext>1</mtext><mtext>(\alpha \; ?\; \alpha \prime )</mtext>}}$, $\text{φ}{}_2\text{(x, n) = A[x}{}^{\mathrm{\alpha }}\text{(x}{}^{\mathrm{\alpha \prime }}\text{? Kn}{}^{\mathrm{<mtext>\alpha \prime </mtext><mtext>\theta </mtext>}}\text{)]}{}^{\mathrm{<mtext>1</mtext><mtext>(\alpha \; +\; \alpha \prime )</mtext>}}$. Both of these expressions are in good agreement with a large array of partial masking data.     

Results of a preliminary survey of computer users in psychological laboratories

A short questionnaire was distributed to a subset of the computer users connected with the National Conference on the Use of On-Line Computers in Psychology to determine the type of computer equipment used by psychologists and the current uses of that equipment. The results of this pilot study are discussed in this paper.     

Percepts of rigid motion within and across apertures.

Humans consistently err in their percepts of rotational motion viewed through an aperture. Such errors provide insight into the constraints observers use to interpret retinal images. In the 1st of 2 experiments, Ss consistently perceived the fixed center of rotation for an unmarked line viewed through an aperture as located on the line, regardless of its actual location. Accuracy greatly improved with visible line endings. This finding was extended to explain why a square appears nonrigid when it rotates behind a partial occluder. This illusion may result from observers misperceiving the center of rotation of the unmarked square sides. In this situation, Ss seemed unable to apply an object rigidity constraint across apertures. These findings support a conceptualization of the visual system in which consistent local information must be clearly present before prior knowledge can be used to interpret retinal stimulation.