Mapping the color space of saccadic selectivity in visual search

Color coding is used to guide attention in computer displays for such critical tasks as baggage screening or air traffic control. It has been shown that a display object attracts more attention if its color is more similar to the color for which one is searching. However, what does similar precisely mean? Can we predict the amount of attention that a display color will receive during a search for a given target color? To tackle this question, two color‐search experiments measuring the selectivity of saccadic eye movements and mapping out its underlying color space were conducted. A variety of mathematical models, predicting saccadic selectivity for given target and display colors, were devised and evaluated. The results suggest that applying a Gaussian function to a weighted Euclidean distance in a slightly modified HSI color space is the best predictor of saccadic selectivity in the chosen paradigm. Hue and intensity information by itself provides a basis for useful predictors, spanning a possibly spherical color space of saccadic selectivity. Although the current models cannot predict saccadic selectivity values for a wide variety of visual search tasks, they reveal some characteristics of color search that are of both theoretical and applied interest, such as for the design of human–computer interfaces.     

慢性应激对大鼠行为和免疫细胞热休克蛋白70表达的影响

目的：研究慢性不确定应激对大鼠急性整体热水浴后外周血和脾脏免疫细胞热休克蛋白70（Heat shock protein 70, HSP70）表达的影响。方法：随机将大鼠分成慢性应激组和控制组（每组14只）。通过4周的慢性不确定性应激诱发实验组大鼠明显的抑郁行为,此期间控制组大鼠正常饲养。随后给予大鼠42度整体热水浴刺激,维持直肠温度41度25min。热刺激后6h,采用流式细胞仪测定大鼠外周血和脾脏免疫细胞HSP70 水平。结果：与控制组大鼠相比,慢性应激大鼠在急性热刺激后HSP70合成明显减少。控制组大鼠的所有被检测的免疫细胞热应激后HSP70合成均明显增加。相反,慢性应激大鼠仅在外周血的单核细胞和粒细胞检测到HSP70合成增加,同时升高的水平明显低于控制组大鼠。结论：慢性应激降低大鼠免疫细胞HSP70的热诱导反应,提示HSP70保护性作用减弱可能参与了慢性应激损害免疫细胞功能的生物学过程     

早期应激对抑郁相关行为及神经内分泌反应的长期影响

临床研究发现,早期创伤性经历是导致成年抑郁症易感性增加的高风险因素之一。但早期应激通过何种途径对抑郁发病产生长期的影响,目前尚不清楚。本文综述了近年来有关的实验动物研究,从早期应激的动物模型建立、早期应激对成年动物抑郁相关行为及神经内分泌反应的长期影响等方面进行了系统论述和分析,进而提出了早期应激并不影响动物的本能行为,但早期应激影响与行为动机和应激应对等认知相关的行为的观点,进一步论证了早期应激是通过增加个体潜在的易患病素质对抑郁症发病产生影响     

Making Numbers Come to Life: Two Scoring Methods for Creativity in Aurora's Cartoon Numbers

Although creativity has long been recognized as an important aspect of mathematical thinking, both for the advancement of the field and in students' developing expertise in mathematics, assessments of student creativity in that domain have been limited in number and focus. This article presents an assessment developed for creativity that provides a score for mathematical creativity (MaC) in addition to a score for general creativity in the numeric domain, or what we might call numerical creativity (NuC). We developed different rating scales for each and then explored how each scoring method accounts for the students' mathematical/numerical and creative skills. The psychometric properties for both scoring approaches were examined. Each method was shown to reflect different relationships with other performance tests. In addition, it is proposed that MaC may provide useful insight into students' levels of adaptive expertise in mathematics, as reflected by their ability to apply mathematical knowledge (i.e., language, operations, concepts) to novel situations, representing an informative supplement to performance indicators of math achievement.     

Instantiation as location

Many familiar forms of property realism identify properties with sui generis ontological categories like universals or tropes and posit a fundamental instantiation relation that unifies objects with their properties. In this paper, I develop and defend locationism, which identifies properties with locations and holds that the occupation relation that unifies objects with their locations also unifies objects with their properties. Along with the theoretical parsimony that locationism enjoys, I argue that locationism resolves a puzzle for actualists regarding the ontological status of uninstantiated properties. I also note some promising applications of the locationist framework to the metaphysics of quantities and possible worlds.     

微生态药物防治儿童感染性疾病

微生态药物包括益生物、益生菌及其复方产品合生素。国外大量临床随机对照试验结果已肯定此类药物用于儿童消化道感染、呼吸道感染等各类感染及 H IV母婴传播等疾病状态中的疗效。微生态药物用于普通婴幼儿群体是安全的,但用于免疫缺陷、患有某些基础疾病、处于临床危象的患儿或早产儿应谨慎。这是由于益生菌为活体,对于其潜在风险如传递细菌耐药、肠道菌群易位及其诱生性感染、诱发乳酸酸中毒和对肠道菌群的长期不良影响等,都需要在临床中仔细体察。本文重点回顾近10年来益生菌、合生素预防和治疗儿童感染性疾病的临床进展。     

网络突发事件中的负性偏向：产生与表现

在网络突发事件的产生和传播中, 人们往往更关注负面信息的加工和传递, 存在负性偏向。本研究依据事件酝酿、爆发、蔓延阶段的特征, 构建心理机制模型, 通过3项研究分别检验了信息内容、信息加工和信息传递中负性偏向的产生和发展。结果表明, 负性偏向不仅产生于网络突发事件的源头语篇中, 还产生于个体信息加工和人际信息传递过程, 表现为个体对负性词汇更好的记忆效果及更高的辨别力, 以及网民间对负性信息的选择性传递和对模糊信息的负性解读。研究有利于认识网络突发事件信息传播规律, 科学应对舆情危机, 创新网络治理。