Glucocorticoid receptor interaction with Hsp90 remains unaltered after whole body hyperthermia

The influence of 41 degrees C whole body hyperthermic stress on glucocorticoid receptor (GR) association with 90-kDa heat shock protein (Hsp90) in the rat liver cytosol was examined. Total cytosolic GR and Hsp90 concentrations, as well as the amount of Hsp90 co-immunoprecipitated with the GR were determined by quantitative Western blotting using BuGR2 as anti-GR and AC88 as anti-Hsp90 monoclonal antibody. After exposure of the animals to the heat stress, the level of cytosolic Hsp90 increased, while its ratio to apo-receptor within non-activated GR heterooligomeric complexes remained unaltered. Therefore, the Hsp90 recruitment by the GR was not dependent on Hsp90 total cytosolic concentration.     

Documentary Bioethics: Visual Narratives for Generations X and Y

Narrative bioethics is primarily understood to involve storytelling through the use of literature. This article suggests that other forms of media are necessary to convey stories of an ethical nature to an audience broader than one being trained as medical professionals. "Documentary bioethics" is a manner to present and interpret stories of an ethical nature using forms of popular electronic media in a reality-based documentary style to society at large, specifically Generations X and Y.     

Parallel versus serial processing and individual differences in high-speed search in human memory

Many mental tasks that involve operations on a number of items take place within a few hundred milliseconds. In such tasks, whether the items are processed simultaneously (in parallel) or sequentially (serially) has long been of interest to psychologists. Although certain types of parallel and serial models have been ruled out, it has proven extremely difficult to entirely separate reasonable serial and limited-capacity parallel models on the basis of typical data. Recent advances in theory-driven methodology now permit strong tests of serial versus parallel processing in such tasks, in ways that bypass the capacity issue and that are distribution and parameter free. We employ new methodologies to assess serial versus parallel processing and find strong evidence for pure serial or pure parallel processing, with some striking apparent differences across individuals and interstimulus conditions.     

Family predictors of antisocial behavior in adolescence

The goal of the present study was to examine the combined and unique ability of different aspects of family functioning to predict involvement in antisocial behavior in a large nonclinical (community) sample of adolescents. Distinction was made between global (e.g., family socioeconomic status), distal (dispositional characteristics of parents), contextual (family characteristics), and proximal (parent-child interaction) factors that operate within families. Results show that proximal factors were significant predictors of antisocial behavior, independent of their shared variance with other factors. Consistent with the hypothesized mediational model, the effects of distal and contextual factors appear to be mostly indirect: after their association with proximal factors was taken into account, these factors were no longer significantly related to antisocial behavior. The implications of these findings for planning of developmentally appropriate interventions for adolescents and their families are discussed.     

Obtaining funding for new researchers in psychology

A mentor is the key person to assist a student who wishes to become an independent investigator. The federal government provides long-term funding for decades of research by an investigator, and short-term funding for years of transition from student to investigator is available from both governmental and private agencies. Grants designed for men and women and various ethnic groups are valuable resources. Courteous acknowledgment of sponsorship by the grantee facilitates continued grants from the funding source.     

Size perception by vision and kinesthesia

When two sizes, one perceived by vision and the other by kinesthesia, are apparently equal, the physical relationship between them varies: The sizes may be equal, or the visual size may be larger than the kinesthetic size, or vice versa. In this study, the method of cross-modal matching and the method of magnitude production were used to explore the relationship between apparently equal sizes (5–40 cm) perceived by vision and by kinesthesia. The sizes were linear or circular, and the mode of standard presentation was visual, kinesthetic, or verbal. The size and the direction of the intermodal mismatch varied with the size of the standard. It was also found that an apparent length of movement varied with the direction of movement. In all conditions, the relationship between apparently equal visual and kinesthetic sizes was well approximated by a power function.     

Traumatization of group leaders in their work with displaced persons

Displaced persons are a special, threatened group of people, participants in this war, who were suddenly forced to abandon their homes. The majority of them were, overnight, left without anything they had, some even without their closest family. They all have one thing in common: they have all lost so much. Work with such people is directed toward overcoming their feelings of loss and abandonment and preventing psychical decompensation. Groups of displaced persons temporarily sheltered in the Rijeka region have been observed to be markedly regressed, with increased sensitivity, a low degree of tolerance, great demands on society and strongly expressed projective tendencies. Therapists suffer personal traumatization in working with displaced persons. This paper describes the reactions and feelings of group leaders caused by manifestations of group dynamics in different phases of exile.     

Structural family therapy with Mexican-American family systems

Characteristics of traditional Mexican-American families with consequent family rules that affect these family systems are discussed along with selected clinical cases. The specific cases discussed involve: (1) interactions with family of origin in intercultural marriages, (2) intracultural differences in levels of acculturation and traditional family rules, and (3) extended family impact in response to severe life crisis. The development of therapeutic processes from structural and strategic family therapy approaches, which reflect appreciation for cultural differences and strengths, is suggested.This material was presented at the annual meeting of the Texas Association for Marriage and Family Therapy, January, 1994, San Antonio, TX.     

Spirituality and intentions to engage in Covid-19 protective behaviours

Accumulating evidence points to spirituality as a belief system that contributes to low trust in science, with self-identified spiritual individuals reporting high levels of unwarranted scepticism towards science in general and vaccination specifically. We investigated whether self-identified spirituality also predicts intentions to engage with Covid-19 protective measures during the pandemic. In Studies 1–3 (N = 774), we asked participants to report their spirituality and desire to be vaccinated against Covid-19 shortly after the first vaccine rollout. In Studies 2–3, we included measures of scepticism towards and intentions to comply with Covid-19 prevention measures (handwashing, wearing face coverings, distancing). As expected, stronger self-reported spirituality involved lower desire to be vaccinated, controlling for various worldview and demographic variables. Yet, we found no evidence for spirituality to predict scepticism towards other Covid-19 preventative behaviours or intentions to engage with them. Our findings corroborate and extend previous literature on science rejection, demonstrating that spirituality is uniquely involved in vaccine rejection.     

More than words: Rethinking sustainability communications through neuroscientific methods

In the era when the overarching problem of climate change, threatening the entire humanity and all life on earth, demands actions and behavioural change from all of the societal agents, including governments, organizations, companies and individuals, the world fails to achieve unity on the matter of existence of the problem, cause of the problem and on the solution of the problem. Since the scientific consensus on climate change is achieved, this article tries to examine why it is so hard to convey the message of needed behavioural change. The neuromarketing study presented in this article focuses on marketing communications that try to convey the message that would lead to the consumers' mental, emotional and behavioural change. Effectiveness of the branded environmental videos was evaluated utilizing the neuroscience approach. Electroencephalogram and an eye-tracking device were used to register the implicit brain reactions of the study participants viewing the branded videos. For comparison reasons, the branded videos selected for the study use two different approaches for conveying the message. The first approach relies on narrative, words and logic, whilst the second one appeals primarily to emotions. The aim of the study was to answer the question whether the words are enough or is there more to it?