Accepting the Challenge of John Finley Scott

Although high school counselors are frequently confronted with challenging situations, there are perhaps few researchers, if any, who have been more direct in their attack on high school counselors than John Finley Scott. In his 1966 publication “So You're Going to College!,” he reports findings which indicate that approximately two-thirds of those college students he researched found their high school counselors among the persons who gave them the worst advice about going to college. This study is an attempt to explore the consistency of such findings, by attempting a similar study at a different university located in a different section of the United States.     

Brain-stimulation reward: a review

During most of the first half of this century psychologists knew what they wanted to do but had no idea how to do it, and during the second half they have, for the most part, been so preoccupied with how to do it that they have forgotten what they wanted to do. When J. Olds and Milner (1954) announced that rats would stimulate themselves in the septal area, it appeared to open the door to understanding motivation and reinforcement in terms of the underlying physiology. In the ensuing 36 years some progress has been made in that direction, though far outstripped by the progress in methodology. In this review I trace the efforts that have been made to locate the structures involved in self-stimulation by lesions, drugs, determinations of their neurophysiological characteristics, and other more sophisticated methods. I then review experiments, none very recent, comparing brain-stimulation reward to natural rewards and finally indicate how the information so far collected may be incorporated into theories of learning and motivation.     

Insights into blindsight

Toward a science of consciousness (Tucson III): 27 April-2 May 1998, Tucson, Arizona, USA.     

Streams and consciousness: visual awareness and the brain

Vision is our most powerful sense and, arguably, it gives us our most vivid sensory and imaginal experiences. It is also one of the best understood systems in contemporary neuroscience. Yet, contrary to both traditional assumptions and our phenomenological intuition, recent research has shown that vision is not a monolithic system that creates a single general-purpose representation in the brain. For example, selective brain damage can compromise visuomotor control while leaving perception intact, and damage elsewhere can compromise visual perception while leaving visuomotor control intact. Thus, it is becoming apparent that we have two (largely) separate visual systems. One of them is dedicated to the rapid and accurate guidance of our movements: it is a complex and powerful system, and yet it lies outside the realm of our conscious visual awareness. The other seems to provide our perceptual phenomenology, although its primary purpose is probably to provide suitably coded visual inputs for storage in and retrieval from memory. According to this conceptualization, both systems can be seen as serving our behaviour, but each does so on a different time scale. Recent studies suggest that neuropsychological research in humans can play a central role in bridging the gap between neurobiological studies of the monkey's visual system and the search to narrow down the brain mechanisms that mediate our visual awareness.     

The worker scale: Developing a measure to explain gender differences in behavioral self-handicapping

Research has consistently found that men engage in more behavioral self-handicapping than do women. We first review evidence suggesting that these gender differences result from women placing more importance on displaying effort than do men. We then present the results of two studies seeking to develop measures of beliefs about effort that might explain these gender differences in behavioral self-handicapping. Women, across a wide range of measures, placed more importance on effort than did men. However, only a new measure of more personalized effort beliefs, dubbed the Worker scale, uniquely explained gender differences in dispositional tendency to behaviorally self-handicap. The Worker scale also predicted academic performance, consistent with the notion that these effort beliefs would predict engagement in actual behavioral self-handicaps that undermine performance.     

Suicidal Behavior in the Western Pacific Region: Characteristics and Trends

Current knowledge of suicidal behavior in the Western Pacific region is relatively limited when compared to other areas of the world. This area is characterized by a wide diversity of social, economic, and cultural aspects that do not permit any homogenous reading of suicide phenomena. Data from countries of the region included in this article suggest the existence of important differences among nations in terms of gender, age, and methods of suicide, as well role of mental illness. In addition, the Western Pacific region appears to be affected by higher rates of suicide than other areas in the world, with signs of progressive worsening in recent years and worrying predictions for the next two decades. The Suicide Trends in At‐Risk Territories (START) Study, initiated by the World Health Organization Regional Office in Manila, seeks to research the incidence of both fatal and nonfatal suicidal behavior in countries of the region and to implement interventions for suicide attempters. This ambitious project is expected to standardize data collection procedures and improve the knowledge cultural factors in suicide.     

Humanistic psychology: Saybrook institute graduate school and research center

This article attempts to resolve the apparent tensions between humanistic and positive psychology regarding their respective notions of what constitutes a good life. It argues that an ethic of authenticity provides a unifying normative framework for both traditions, including interpretations of the various dimensions of authenticity and of the moral virtues and principles associated with this ethical ideal. The article provides a working definition of authentic selfhood that draws on both the existential-phenomenological tradition and the communitarian ethical framework associated with positive psychology. It demonstrates how these two very different philosophical traditions contribute to a shared, integrative theory of authentic self-development which, in turn, provides needed clarity to the normative framework of positive psychology.     

Angiotensin II differentially affects hippocampal glial inflammatory markers in young adult male and female mice

Hypertension is a risk factor for neurodegenerative disorders involving inflammation and inflammatory cytokine-producing brain cells (microglia and astrocytes) in the hippocampus and medial prefrontal cortex (mPFC). Here we investigated the effect of slow-pressor angiotensin II (AngII) on gliosis in the hippocampus and mPFC of young adult (2-mo-old) male and female mice. In males, AngII induced hypertension, and this resulted in an increase in the density of the astrocyte marker glial fibrillary acidic protein (GFAP) in the subgranular hilus and a decrease in the density of the microglial marker ionized calcium binding adapter molecule (Iba-1) in the CA1 region. Females infused with AngII did not show hypertension but, significantly, showed alterations in hippocampal glial activation. Compared with vehicle, AngII-infused female mice had an increased density of Iba-1 in the dentate gyrus and CA2/3a region. Like males, females infused with AngII exhibited decreased Iba-1 in the CA1 region. Neither male nor female mice showed differences in GFAP or Iba-1 in the mPFC following AngII infusion. These results demonstrate that the hippocampus is particularly vulnerable to AngII in young adulthood. Differences in gonadal hormones or the sensitivity to AngII hypertension may account for divergences in GFAP and Iba-1 in males and females.

Hypertension is a significant risk factor for neurological disorders such as Alzheimer''s disease (AD) that are associated with neurodegeneration and cognitive decline (Daugherty 2021). Hypertension can develop during the life span yet is often studied at middle and late life. There is emerging evidence that hypertension is becoming more common in late adolescence and early adulthood (Azegami et al. 2021; Hamrahian and Falkner 2022). In addition, there is increasing awareness that the duration of hypertension can impact the onset of neural degeneration (Schaare et al. 2019; Yang et al. 2021) and cognitive dysfunction (Yaffe et al. 2014, 2021; Mahinrad et al. 2020; Zhou et al. 2022). Although the age of onset of hypertension may influence the trajectory of degenerative disease in later life, the effect of hypertension on brain health in young adult subjects is relatively underinvestigated.Hippocampal and medial prefrontal cortical pathology are commonly present in neurodegenerative diseases like AD (Belonwu et al. 2021). Structurally and functionally, both the hippocampus and mPFC also are compromised during hypertension (Raz et al. 2007; Gonzalez et al. 2015; Bu et al. 2018). In the hippocampus, hypertension is known to disrupt cerebrovascular function, promote inflammatory processes, and contribute to neuronal impairment and cognitive decline (Iulita et al. 2018). Although less studied than the hippocampus, the PFC is also compromised by hypertension (Raz et al. 2007; Bu et al. 2018; Wang et al. 2020).Microglia, the resident macrophages in the brain, have been implicated in inflammatory states, cognitive function (Cornell et al. 2022), and the brain''s response to hypertension (Calvillo et al. 2019; Li et al. 2020). An increase in the density of ionized calcium binding adapter molecule (Iba-1), a protein constitutively expressed in microglia and up-regulated when microglia enter an activated stage (Imai et al. 1996; Sasaki et al. 2001), is commonly reported in models of cognitive and neurodegenerative disorders (Prinz et al. 2021).In addition to microglia, astrocytes also have been implicated in the emergence of hippocampal and cortical dysfunction. Astrocytes play critical roles in blood–brain barrier (BBB) formation; brain metabolic, ion, and water homeostasis; neurotransmitter recycling; synapse formation; and neuroimmune signaling (Matias et al. 2019). In the context of insult, pathogen infection, or neurological disease, astrocytes undergo functionally complex reactive responses (Chiu et al. 2014; Giovannoni and Quintana 2020) that are associated with an increase in glial fibrillary acidic protein (GFAP) gene and protein expression (Crespo-Castrillo et al. 2020; Sofroniew 2020).To better understand the consequences of elevated blood pressure on the young adult brain, we conducted an exploratory investigation of the impact of hypertension on the expression of microglia and astrocyte markers—Iba-1 and GFAP, respectively—in the hippocampus and mPFC of male mice. Mice were exposed to angiotensin II (AngII) using the “slow-pressor” model (Dickinson and Lawrence 1963), which in males mimics the gradual rise in blood pressure and increase in sympathetic activation (Grassi and Ram 2016; Lerman et al. 2019) characteristic of essential hypertension (Lerman et al. 2019). Significantly, there is an important sex dimorphism in the risk for hypertension. Compared with men, women are protected from hypertension before middle age but become increasingly affected as they reach perimenopause, and intact young female rodents show a reduced sensitivity to AngII hypertension (Van Kempen et al. 2016). Similarly, there are sex differences in the incidence, progression, and severity of hypertension-associated neurodegenerative disease (Lopez-Lee et al. 2021). Furthermore, sex differences in glial function have also been documented within the context of neurodegenerative diseases (Kodama and Gan 2019; Biechele et al. 2020). Given this evidence, the effect of AngII on hippocampal and medial prefrontal cortical glial markers also was investigated in young intact female mice.     

Frontal plane multi-segment foot kinematics in high- and low-arched females during dynamic loading tasks

The functions of the medial longitudinal arch have been the focus of much research in recent years. Several studies have shown kinematic differences between high- and low-arched runners. No literature currently compares the inter-segmental foot motion of high- and low-arched recreational athletes. The purpose of this study was to examine inter-segmental foot motion in the frontal plane during dynamic loading activities in high- and low-arched female athletes. Inter-segmental foot motions were examined in 10 high- and 10 low-arched female recreational athletes. Subjects performed five barefooted trials in each of the following randomized movements: walking, running, downward stepping and landing. Three-dimensional kinematic data were recorded. High-arched athletes had smaller peak ankle eversion angles in walking, running and downward stepping than low-arched athletes. At the rear-midfoot joint high-arched athletes reached peak eversion later in walking and downward stepping than the low-arched athletes. The high-arched athletes had smaller peak mid-forefoot eversion angles in walking, running and downward stepping than the low-arched athletes. The current findings show that differences in foot kinematics between the high- and low-arched athletes were in position and not range of motion within the foot.