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151.
Iván Márquez-Rodas Sara López-Tarruella Yolanda Jerez Mercedes Cavanagh Sara Custodio Daniel López-Trabada Beatriz Moya Sara Pérez Ana B. Rupérez Miguel Martín 《Journal of genetic counseling》2014,23(1):108-113
A comprehensive family history is essential to identify patients at risk for hereditary cancer who could benefit from genetic counseling (GC). In a previous study, we observed a low occurrence of family history record (FHR) collection rate and GC referral among oncologists at our institution. The present work analyzes whether the implementation of a heredofamilial cancer unit (HFCU) would improve these parameters. We retrospectively compared the FHR rate in clinical records, National Cancer Institute (NCI) general criteria for hereditary cancer suspicion, GC referrals and FHR quality in two cohorts: cohort 1 (patients diagnosed before HFCU creation) and cohort 2 (after HFCU creation). Of 1,175 patients (590 cohort 1 and 585 cohort 2), FHRs were consigned in 27.3 % and 52.5 % of patients, respectively (p?<?0.001). The GC referral of patients with any NCI criterion was 13.6 % xin cohort 1 vs. 40.5 % in cohort 2 (p?<?0.001). FHR quality improved in terms of the total number of relatives (164 vs. 314, p?=?0.1, N.S.) and number of healthy relatives consigned (80 vs. 191, p?<?0.01). Nine mutations (6 BRCA, 1 MEN1, 2 Lynch), 4 unknown significance variants (all in BRCA) and 2 with no mutation were identified among patients referred from cohort 2. We conclude that the creation of a heredofamilial cancer unit has changed both FHR and GC referrals among oncologists at our institution, although continuous educational efforts are required. 相似文献
152.
How orthographic transparency affects morphological processing in young readers with and without reading disability 下载免费PDF全文
This study investigates how orthographic modifications to the stems of complex words affect morphological processing in proficient young Spanish readers and children with reading deficits. In a definition task all children, irrespective of their reading skill, were worse at defining derived words that had an orthographic alteration of the base stem than words with no orthographic alteration. In a go/no‐go lexical decision task, an interaction between base frequency and orthographic alteration was found: base frequency affected derived words with no orthographic alteration more than words with alterations, irrespective of reading skill. Overall, results show that all children benefit from a high frequency base, skilled children outperform children with reading deficits and morphological processing is affected by orthographic alterations similarly in proficient and impaired readers. 相似文献
153.
The Effects of Motor and Vocal Response Interruption and Redirection on Vocal Stereotypy and Appropriate Vocalizations 下载免费PDF全文
Stereotypy has been defined as repetitive vocal or motor behaviors that are noncontextual with invariant topographies. One intervention to reduce vocal stereotypy and increase appropriate vocalizations is response interruption and redirection (RIRD). Previous research has suggested that RIRD's behavioral mechanism consists of punishment. The purpose of this study was to extend this research by comparing two procedures, namely, vocal and motor RIRD contingent upon the occurrence of vocal stereotypy and to evaluate concomitant increases in appropriate vocalizations. A multiple treatment reversal design was used to compare the effectiveness of both interventions on five children diagnosed with an Autism Spectrum Disorder. Results suggested that both demand topographies were equally effective in reducing vocal stereotypy and increasing appropriate vocalizations. This research replicates previous findings that have suggested that RIRD is a punishment procedure. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
154.
Prior Publication and Redundancy in Contemporary Science: Are Authors and Editors at the Crossroads?
We discuss prior publication and redundancy in contemporary science in the context of changing perceptions of originality in the communication of research results. These perceptions have been changing in the publication realm, particularly in the last 15 years. Presenting a brief overview of the literature, we address some of the conflicts that are likely to arise between authors and editors. We illustrate our approach with conference presentations that are later published as journal articles and focus on a recent retraction of an article that had been previously published as a conference proceedings. Although we do not make definitive pronouncements on the matter—as many concepts are evolving—we do argue that conference papers that contain sufficient details for others to attempt a replication and are indexed in scientific databases such as PubMed, challenge some currently held assumptions of prior publication and originality in the sciences. Our view is that these important issues are in need of further clarification and harmonization within the science publishing community. This need is more evident when we consider current notions of research integrity when it comes to communication to peers. Revisiting long-standing views about what constitutes prior publication and developing a clearer set of guidelines for authors and editors to follow should reduce conflicts in the research environment, which already exerts considerable pressure, especially on newcomers in academia. However, while clearer guidelines are timely, developing them is only part of the challenge. The present times seem to call for deeper changes in the research and publication systems. 相似文献
155.
Emily K. Langton Caio F. Miguel Jocelyn E. Diaz Maria Clara Cordeiro Megan R. Heinicke 《Journal of applied behavior analysis》2020,53(3):1466-1484
Twelve college students learned to tact the names of notes and rhythms and play them when presented with compound stimuli (visuals of notes and rhythms on a musical staff). In Experiment 1, we assessed generalization by presenting novel notes, rhythms, and compound stimuli not previously paired together. In the second experiment, we added a metronome that played at 60 beats per minute in all conditions for 3 out of 6 participants to ensure consistent tempo. Across both experiments, participants passed almost all posttests with the exception of tacting and playing in the presence of sound clips. Our data suggest that matrix training is an effective procedure to teach music skills to college students. 相似文献
156.
157.
Analysis of the Impact of Creative Technique on the Motivation of Physical Education Students in Dance Content: Gender Differences 下载免费PDF全文
Diana Amado Fernando Del Villar Pedro Antonio Sánchez‐Miguel Francisco Miguel Leo Tomás García‐Calvo 《创造性行为杂志》2016,50(1):64-79
The aim of this study was to learn about the effectiveness of two dance teaching techniques, the creative examination technique and the direct instruction technique, on the satisfaction of basic psychological needs, the level of self‐determination, the perception of usefulness, enjoyment and effort of physical education students. Likewise, it purports to analyze the gender difference in the psychological variables addressed in agreement with the teaching technique used, to guide and personalize the treatment of these contents in physical education. A quasi‐experimental design was carried out with four natural groups from two school centers. The direct instruction technique was applied with two groups and the creative examination technique with the other two, in a total of 12 sessions. An initial and final measurement was taken in both groups, and the results revealed the complexity to motivate students after 12 sessions. However, the gender‐dependent analyses offer methodological guidelines, as the creative technique causes adaptative consequences on the male gender and disadaptative consequences on the female gender. By way of conclusion, we can highlight the need to devote more sessions to dance teaching and to apply different treatments depending on the gender. 相似文献
158.
Eleni Matechou Ivy Liu Daniel Fernández Miguel Farias Bergljot Gjelsvik 《Psychometrika》2016,81(3):611-624
The work in this paper introduces finite mixture models that can be used to simultaneously cluster the rows and columns of two-mode ordinal categorical response data, such as those resulting from Likert scale responses. We use the popular proportional odds parameterisation and propose models which provide insights into major patterns in the data. Model-fitting is performed using the EM algorithm, and a fuzzy allocation of rows and columns to corresponding clusters is obtained. The clustering ability of the models is evaluated in a simulation study and demonstrated using two real data sets. 相似文献
159.
Miguel A. Verdugo Alba Aza María Begoña Orgaz María Fernández Antonio M. Amor 《International Journal of Clinical and Health Psychology》2021,21(2):100219
Background/ObjectiveAfter an acquired brain injury (ABI), the person remains with several impairments and disabilities that cause a decrease in his/her quality of life (QoL), which could change over time. The objective of the study was to analyse the evolution patterns of QoL in a sample of persons with ABI for one-year as well as the differences in proxy- and self-report versions of a QoL instrument. Method: The sample comprised 402 persons with ABI with ages ranging between 18 and 91 years, whom 36.20% had had the accident recently (i.e., three years or less). Patients, professionals and relatives responded at three evaluation points to the CAVIDACE scale, an ABI-specific QoL tool. Results: ANOVAs showed an improvement in QoL in the two follow-ups; the improvement was especially significant in the period between baseline and six months. The respondent factor did not interact with the evaluation time, but significant differences were found between respondents, with scores of patients higher than that for proxies. Finally, the QoL’s evolution interacts with the time elapsed since injury, showing significant improvements in the most recent group (i.e., three years or less). Conclusions: QoL must be considered from the earliest moments after ABI to obtain more significant improvements. 相似文献
160.
Fei Hanlan de Guinea Miguel Yang Li Chapman Colin A. Fan Pengfei 《Animal cognition》2022,25(4):891-903
Animal Cognition - Finding suitable sleeping sites is highly advantageous but challenging for wild animals. While suitable sleeping sites provide protection against predators and enhance sleep... 相似文献