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211.
Contextual and serial discriminations: a new learning paradigm to assess simultaneously the effects of acute stress on retrieval of flexible or stable information in mice 总被引:3,自引:0,他引:3
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Célérier A Piérard C Rachbauer D Sarrieau A Béracochéa D 《Learning & memory (Cold Spring Harbor, N.Y.)》2004,11(2):196-204
The present study was aimed at simultaneously determining on the same subject, the effects of stress on retrieval of flexible (contextual or temporal) or stable (spatial) information. Three behavioral paradigms carried out in a four-hole board were designed as follows: (1) Simple Discrimination (SD), in which mice learned a single discrimination; (2) Contextual and Serial Discriminations (CSD), in which mice learned two successive discriminations on two different internal contexts; (3) Spatial Serial Discriminations (SSD), in which mice learned two successive discriminations on an identical internal context. The stressor (three inescapable electric footshocks) was delivered 5 min before retention, occurring 5 min or 24 h after acquisition. Results showed that this stressor increased plasmatic corticosterone levels and fear reactivity in an elevated-plus-maze, as compared with nonstressed mice. The stressor reversed the normal pattern of retrieval observed in nonstressed controls in the CSD task, this effect being context dependent, as it was not observed in the SSD task. Overall, our study shows that stress affected the retrieval of flexible and old information, but spared the retrieval of stable or recent ones. Therefore, these behavioral paradigms allow us to study simultaneously, on the same animal, the effects of stress on distinct forms of memory retrieval. 相似文献
212.
Spatio-temporal configurations of distributed activity in the brain is thought to contribute to the coding of neuronal information and synaptic contacts between nerve cells could play a central role in the formation of privileged pathways of activity. Synaptic plasticity is not the exclusive mode of regulation of information processing in the brain, and persistent regulations of ionic conductances in some specialized neuronal areas such as the dendrites, the cell body, and the axon could also modulate, in the long-term, the propagation of neuronal information. Persistent changes in intrinsic excitability have been reported in several brain areas in which activity is elevated during a classical conditioning. The role of synaptic activity seems to be a determinant in the induction, but the learning rules and the underlying mechanisms remain to be defined. We discuss here the role of synaptic activity in the induction of intrinsic plasticity in cortical, hippocampal, and cerebellar neurons. Activation of glutamate receptors initiates a long-term modification in neuronal excitability that may represent a parallel, synergistic substrate for learning and memory. Similar to synaptic plasticity, long-lasting intrinsic plasticity appears to be bidirectional and to express a certain level of input or cell specificity. These nonsynaptic forms of plasticity affect the signal propagation in the axon, the dendrites, and the soma. They not only share common learning rules and induction pathways with the better-known synaptic plasticity such as NMDA receptor dependent LTP and LTD, but also contribute in synergy with these synaptic changes to the formation of a coherent engram. 相似文献
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214.
Paredes RG 《Scandinavian journal of psychology》2003,44(3):203-212
The medial preoptic area/anterior hypothalamus (MPOA/AH) is a brain site derived from proliferative zones from the diencephalon and telencephalon. It is probably this characteristic that makes this brain region participate in different physiological and behavioral functions. The present review addresses the role of the MPOA/AH in the control of male sexual behavior. It is clear that the MPOA/AH is a crucial site in the control of sexual behavior in males of all species studied to date. But although many different publications have followed the contribution of Heimer and Larsson there is no agreement as to what is specifically the role of the MPOA/AH in sexual behavior. At least three hypotheses have been presented. The first one suggests that this brain region is involved in the consummatory aspects (execution) of sexual behavior. The second indicates that the MPOA/AH is involved in the appetitive components (motivation) of masculine sexual behavior. The third hypothesis considers that MPOA/AH neurons are involved in the regulation of consummatory and appetitive aspects of sexual behavior. From the literature reviewed, it will become evident that the evidence supporting a role of the MPOA/AH in the execution of sexual behavior is based on a number of limited studies not easy to interpret. On the other hand, several lines of evidence using a variety of methodologies support the notion that the MPOA/AH is involved in the motivational aspects of male sexual behavior. 相似文献
215.
The ease with which printed words are recognized depends on the position at which the eyes initially fixate the word. In this study, we examined to what extent recognition performance for each fixation position depends on the average visibility of the word's constituent letters. Experiment 1 measured recognition performance to single letters embedded in strings of Xs (lengths of 5 and 7) for all combinations of letter position and initial fixation position in the string. In Experiment 2, recognition performance was measured for five-letter and seven-letter words as a function of initial fixation position in the word. Whereas average letter visibility showed a symmetric function in Experiment 1, the word recognition data of Experiment 2 showed the typical asymmetric curve. Combining the letter visibility data with measures of lexical constraint using absolute letter-in-string positions failed to capture the pattern in the word data. An alternative measure of constraint based on relative position coding of letters generated more accurate predictions. 相似文献
216.
A general theory of the relationship of binocular visual space to physical space is formulated within a conjoint measurement framework. Psychophysically motivated invariance relations induce various functional equations. Another class of functional equations arises if we additionally assume the validity of a different psychophysical theory that is based on a formula suggested by A. A. Blank. We solve and interpret most of these equations and point out an unsolved problem. The obtained results lead to a measurement-theoretic foundation of the psychophysical assumptions underlying the Luneburg theory of binocular vision. They also contribute to clarifying the relationship between the presented general theory and Blank's approach. Copyright 1999 Academic Press. 相似文献
217.
The fairness of treatment can be inferred from 2 aspects of the relationship between authority and other party: the person-related aspect and the role-related aspect. One hundred seventy-five American detainees were interviewed about their encounters with police officers and correctional officers. The role-related aspect affected procedural fairness judgments most when first-time incarcerated detainees evaluated the encounter with police officers. The person-related aspect affected procedural fairness judgments most when first-time detainees and repeatedly incarcerated detainees evaluated encounters with correctional officers. Consequences for the group value model of procedural fairness as well as for the legal practice are discussed. 相似文献
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219.
Hand-movement profiles in a tactual—tactual matching task: Effects of spatial factors and laterality
Joël Fagot Agnès Lacreuse Jacques Vauclair 《Attention, perception & psychophysics》1994,56(3):347-355
We examined the effect of spatial factors and hemispheric lateralization upon hand-scanning strategies in 14 right-handed men tested in a tactual—tactual matching task. The experiment involved comparisons (judgments of same or different) between two objects sequentially touched by the fingertips of the left or right hand. Stimuli were made of smoothly joined cubes whose junctions were not haptically discernible. Exploratory strategies were inferred from the durations and locations of hand contacts with any of the cubes composing the stimuli. Accuracy was greater when the same stimulus was touched twice by the same hand than when different hands were used to feel it. With regard to strategies, both hands touched the upper parts of the object longer than the lower parts. Subjects also inspected more portions of the objects ipsilateral to the hand used. Overall differences in time spent touching cubes were greater for the right hand than for the left hand, showing that touch times were less evenly distributed on object parts for the former than for the latter. In this study, the process of information gathering by touch appears to be determined by the intertwining integration of contextual factors (e.g., stimulus position in space), biomechanical constraints on hand movements, and such cognitive factors as hemispheric differences on the ability to encode spatial pattern information. 相似文献
220.
Yannis Papamichaël 《International journal of psychology》1993,28(6):789-808
Cette recherche vise à définir le rôle du milieu culturel dans la substitution d'un outil par un autre instrument dans trois tâches techniques quotidiennes: découpage, dévissage, clouage. Trois catégories de sujets (n = 180) d'âge préscolaire (milieu: gitan, technicien, “favorisé”) ont été testées dans deux conditions expérimentales de substitution: (1) les sujets ont à choisir un instrument adéquat parmi les substituts (11 objets proposés) socialement marqués par leur usage courant; (2) les sujets sont invités à remplacer l'outil manquant par un objet non investi de significations sociales particulières. Les résultats montrent une supériorité générale du milieu gitan dans les deux conditions expérimentales; surtout dans la mesure où le substitut proposé ne se trouve pas investi par les valeurs culturelles propres au mode de vie du groupe social. 相似文献