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991.
Bradley B. Doll James A. Waltz Jeffrey Cockburn Jaime K. Brown Michael J. Frank James M. Gold 《Cognitive, affective & behavioral neuroscience》2014,14(2):715-728
Patients with schizophrenia (SZ) show cognitive impairments on a wide range of tasks, with clear deficiencies in tasks reliant on prefrontal cortex function and less consistently observed impairments in tasks recruiting the striatum. This study leverages tasks hypothesized to differentially recruit these neural structures to assess relative deficiencies of each. Forty-eight patients and 38 controls completed two reinforcement learning tasks hypothesized to interrogate prefrontal and striatal functions and their interaction. In each task, participants learned reward discriminations by trial and error and were tested on novel stimulus combinations to assess learned values. In the task putatively assessing fronto-striatal interaction, participants were (inaccurately) instructed that one of the stimuli was valuable. Consistent with prior reports and a model of confirmation bias, this manipulation resulted in overvaluation of the instructed stimulus after its true value had been experienced. Patients showed less susceptibility to this confirmation bias effect than did controls. In the choice bias task hypothesized to more purely assess striatal function, biases in endogenously and exogenously chosen actions were assessed. No group differences were observed. In the subset of participants who showed learning in both tasks, larger group differences were observed in the confirmation bias task than in the choice bias task. In the confirmation bias task, patients also showed impairment in the task conditions with no prior instruction. This deficit was most readily observed on the most deterministic discriminations. Taken together, these results suggest impairments in fronto-striatal interaction in SZ, rather than in striatal function per se. 相似文献
992.
Silvia?CamporesiEmail author Michael?J?McNamee 《Philosophy, ethics, and humanities in medicine : PEHM》2014,9(1):4
In light of the World Anti Doping Agency’s 2013 Code Revision process, we critically explore the applicability of two of three criteria used to determine whether a method or substance should be considered for their Prohibited List, namely its (potential) performance enhancing effects and its (potential) risk to the health of the athlete. To do so, we compare two communities of human guinea pigs: (i) individuals who make a living out of serial participation in Phase 1 pharmacology trials; and (ii) elite athletes who engage in what is effectively ‘unregulated clinical research’ by using untested prohibited or non-prohibited performance enhancing substances and methods, alone or in combination. Our comparison sheds light on norms of research ethics that these practices exacerbate with respect to the concepts of multiplicity, visibility, and consistency. We argue for the need to establish a proper governance framework to increase the accountability of these unregulated research practices in order to protect the human guinea pigs in elite sports contexts, and to establish reasonable grounds for the performance enhancing effects, and the risks to the health of the athlete, of the methods and substances that might justify their inclusion on the Prohibited List. 相似文献
993.
William Fleeson R. Michael Furr Eranda Jayawickreme Peter Meindl Erik G. Helzer 《Social and Personality Psychology Compass》2014,8(4):178-191
In the early parts of the 20th century, character made up a major part of psychology, specifically of personality psychology. However, an influential observational study of children's moral behavior, conducted by Hartshorne, May, and colleagues in the 1920s, suggested that consistency in morality‐related behavior was lower than many people expected. Some psychologists interpreted such results to mean that there was no consistency in moral behavior and thus that there were no stable, meaningful individual differences in moral behavior – character did not exist. Recent years have witnessed a reinvigoration of character, ethics, and morality as objects of psychological study. Our purpose in this paper is to contribute to this reinvigoration by reviewing the use of the concept of “character” within psychology, considering whether the evidence supports the notion of moral character as a psychological construct, and suggesting new prospects for research on moral character. 相似文献
994.
Michael Schwarz 《Integrative psychological & behavioral science》2014,48(2):211-237
Although the biases and anomalies characterizing psychometric data should serve as conclusive evidence of systematic flaws in scientific methodology, these problems are usually ignored, which reduces empirical psychology to the closed system of its error theory. However, psychometric scores are ambiguous, and response-shifts and fluctuating validities point to fundamental differences in what the measuring-apparatus questionnaire records and how the measuring-apparatus person judges. Therefore, empirical methods fail when psychology requires evidence-based knowledge about cognitive processes and phenomena. Correcting these flaws requires a reassessment of basic scientific premises and careful consideration of Homo sapiens’ biosemiotic heuristics. Based on comprehensive biopsychosocial, data, the author reconstructs the evolutionary axioms of self-referenced cognitions and reveals what is usually obscured by the axioms of normal science. He substantiates the need for a paradigm shift toward basic bio–cultural principles and an evolutionary understanding of human thinking and behavior. 相似文献
995.
John Kingston Shigeto Kawahara Della Chambless Michael Key Daniel Mash Sarah Watsky 《Attention, perception & psychophysics》2014,76(5):1437-1464
Three experiments are reported that collectively show that listeners perceive speech sounds as contrasting auditorily with neighboring sounds. Experiment 1 replicates the well-established finding that listeners categorize more of a [d–g] continuum as [g] after [l] than after [r]. Experiments 2 and 3 show that listeners discriminate stimuli in which the energy concentrations differ in frequency between the spectra of neighboring sounds better than those in which they do not differ. In Experiment 2, [alga–arda] pairs, in which the energy concentrations in the liquid-stop sequences are H(igh) L(ow)–LH, were more discriminable than [alda–arga] pairs, in which they are HH–LL. In Experiment 3, [da] and [ga] syllables were more easily discriminated when they were preceded by lower and higher pure tones, respectively—that is, tones that differed from the stops’ higher and lower F3 onset frequencies—than when they were preceded by H and L pure tones with similar frequencies. These discrimination results show that contrast with the target’s context exaggerates its perceived value when energy concentrations differ in frequency between the target’s spectrum and its context’s spectrum. Because contrast with its context does more that merely shift the criterion for categorizing the target, it cannot be produced by neural adaptation. The finding that nonspeech contexts exaggerate the perceived values of speech targets also rules out compensation for coarticulation by showing that their values depend on the proximal auditory qualities evoked by the stimuli’s acoustic properties, rather than the distal articulatory gestures. 相似文献
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999.
Richard A. Posthuma Michael Charles Campion Michael A. Campion 《European Journal of Work and Organizational Psychology》2018,27(2):168-187
This study presents a taxonomic foundation for research on employee performance management practices based on a comprehensive review of the literature (198 articles and book chapters). The taxonomy consists of 50 practices organized within seven topic categories, including an evaluation of the amount of research evidence supporting each practice. This taxonomic foundation facilitates the aggregation, integration, interpretation, and explanation of performance management research based on a role-theoretic perspective derived from the behavioural approach to strategic human resource management. The proposed direct-linkage path model shows how this taxonomic foundation ties performance management practices to behaviours and results. We build on this Practice – Behaviour – Results (PBR) critical path model with moderators and mediators based on cognitive and social factors identified in the extensive previous research. This PBR model provides a foundation for orderly and structured growth for future research that will enhance the connection between research and improved organizational practices in performance management, as well as a guide to best practices in performance management. 相似文献
1000.