Modulation of tremor amplitude during deep brain stimulation at different frequencies

Rest tremor was quantified in the index finger tip of 16 patients with Parkinson's disease (PD) receiving deep brain stimulation (DBS) of the ventro-intermediate nucleus (Vim) of the thalamus, the subthalamic nucleus (STN), or the internal part of the globus pallidus (GPi) while being off L-dopa for 12h. Clinically, without DBS, tremor amplitude varied from absent to high. Tremor was recorded continuously for about 5 min under three conditions of DBS repeated twice, namely, effective frequency (E), ineffective frequency (I), and no DBS (O). No changes in tremor were observed across conditions in subjects with little or no tremor. However, in subjects with moderate to large amplitude tremor, DBS decreased tremor amplitude to near normal values within a few seconds. Generally, transitions were progressive and occurred with a varying time delay. Occasionally, tremor escaped from control regardless of the stimulation condition considered. In some cases tremor amplitude in one condition appeared to depend on the preceding condition. Finally, the results were reproducible on two consecutive days. We conclude that tremor control with DBS follows specific dynamical rules, which must be compatible with the hypotheses proposed regarding the underlying mechanisms of DBS.     

Neuropsychological Characteristics of Adolescents With Conduct Disorder: Association With Attention-Deficit–Hyperactivity and Aggression

The purpose of this study was to determine whether an association exists between neuropsychological deficits and conduct disorder (CD) with and without concurrent attention-deficit–hyperactivity disorder (ADHD). In addition, we explored the differential neuropsychological performance of aggressive and nonaggressive CD adolescents and the combined effect of this behavioral status and ADHD on performance. Fifty-nine adolescents (mean age of 15.4 years) who met the criteria for CD were compared with 29 controls comparable in age, gender, and socioeconomic status. A neuropsychological battery of current tests measuring executive functions and a battery of language tests were used in the study. Multivariate analyses showed that, compared with controls, CD adolescents had significantly lower verbal skills but did not differ on executive function measures. However, the lower verbal performance of CD adolescents is not explained by the existence of a CD subgroup with concomitant ADHD or aggressiveness. The study confirms with a sample of CD adolescents the association between verbal deficits and antisocial behavior when socioeconomic status is controlled. Our results also demonstrate that CD per se can be a sufficient condition for such deficits.     

Societal Risk Perception Among Children, Adolescents, Adults, and Elderly People

This study reported on mean risk magnitude judgments expressed by French participants aged 8 to 75 years, on a set of 91 hazardous activities, substances, and technologies. It then systematically analyzed the effects of the age factor on the judgments. Between elderly people and young and mature adults, few notable differences were detected. The most important result was that a considerable proportion of the children were able to estimate the risk associated with most items of the present study, and that the linear association between children's ratings and adults' ratings was very high. This finding supports the view that the learning of the risk associated with various technologies, common in society, is a fast process, depending probably much more on exposure to media information and family discussions (socialization) than on exposure to everyday reality.     

Logic and Philosophy of Logic in Wittgenstein

This essay discusses Wittgenstein's conception of logic, early and late, and some of the types of logical system that he constructed. The essay shows that the common view according to which Wittgenstein had stopped engaging in logic as a philosophical discipline by the time of writing Philosophical Investigations is mistaken. It is argued that, on the contrary, logic continued to figure at the very heart of later Wittgenstein's philosophy; and that Wittgenstein's mature philosophy of logic contains many interesting thoughts that have gone widely unnoticed.     

Are Words Easier to Learn From Infant‐ Than Adult‐Directed Speech? A Quantitative Corpus‐Based Investigation

We investigate whether infant‐directed speech (IDS) could facilitate word form learning when compared to adult‐directed speech (ADS). To study this, we examine the distribution of word forms at two levels, acoustic and phonological, using a large database of spontaneous speech in Japanese. At the acoustic level we show that, as has been documented before for phonemes, the realizations of words are more variable and less discriminable in IDS than in ADS. At the phonological level, we find an effect in the opposite direction: The IDS lexicon contains more distinctive words (such as onomatopoeias) than the ADS counterpart. Combining the acoustic and phonological metrics together in a global discriminability score reveals that the bigger separation of lexical categories in the phonological space does not compensate for the opposite effect observed at the acoustic level. As a result, IDS word forms are still globally less discriminable than ADS word forms, even though the effect is numerically small. We discuss the implication of these findings for the view that the functional role of IDS is to improve language learnability.     

Ruminations and Flow: Why Do People with a More Harmonious Passion Experience Higher Well-Being?

Research shows that harmonious and obsessive passion are positively and negatively linked to well-being respectively (e.g., Vallerand et al. in J Personal 75:505?C534, 2007; Psychol Sport Exerc 9:373?C392, 2008). The present study investigated the psychological mechanisms underlying the different impact of the two types of passion on well-being. A theoretical model involving passion, ruminations, flow experiences, and well-being was tested. Results showed that the more people have a harmonious passion, the more they tend to experience flow in their favorite activity, which in turn predicts higher well-being. Obsessive passion did not seem to be systematically linked to flow in the favorite activity. In contrast, the more people have an obsessive passion, the more they tend to ruminate about their passionate activity while engaging in another activity, which did not seem to be systematically the case for people with a harmonious passion. These ruminations are negatively related to flow experiences in the other activity, which are positively associated with well-being. Flow and ruminations thus seem to contribute to the understanding of the link between passion and well-being.     

Context-related call combinations in female Diana monkeys

Non-human primates possess species-specific repertoires of acoustically distinct call types that can be found in adults in predictable ways. Evidence for vocal flexibility is generally rare and typically restricted to acoustic variants within the main call types or sequential production of multiple calls. So far, evidence for context-specific call sequences has been mainly in relation to external disturbances, particularly predation. In this study, we investigated extensively the vocal behaviour of free-ranging and individually identified Diana monkeys in non-predatory contexts. We found that adult females produced four vocal structures alone (‘H’, ‘L’, ‘R’ and ‘A’ calls, the latter consisting of two subtypes) or combined in non-random ways (‘HA’, ‘LA’ and ‘RA’ call combinations) in relation to ongoing behaviour or external events. Specifically, the concatenation of an introductory call with the most frequently emitted and contextually neutral ‘A’ call seems to function as a contextual refiner of this potential individual identifier. Our results demonstrate that some non-human primates are able to increase the effective size of their small vocal repertoire not only by varying the acoustic structure of basic call types but also by combining them into more complex structures. We have demonstrated this phenomenon for a category of vocalisations with a purely social function and discuss the implications of these findings for evolutionary theories of primate vocal communication.     

The bank of standardized stimuli (BOSS): comparison between French and English norms

Throughout the last decades, numerous picture data sets have been developed, such as the Snodgrass and Vanderwart (1980) set, and have been normalized for variables such as name and familiarity; however, due to cultural and linguistic differences, norms can vary from one country to another. The effect due specifically to culture has already been demonstrated by comparing samples from different countries where the same language is spoken. On the other hand, it is still not clear how differences between languages may affect norms. The present study explores this issue by collecting and comparing norms on names and many other features from French Canadian speakers and English Canadian speakers living in Montreal, who thus live in similar cultural environments. Norms were collected for the photos of objects from the Bank of Standardized Stimuli (BOSS) by asking participants to name the objects, to categorize them, and to rate their familiarity, visual complexity, object agreement, viewpoint agreement, and manipulability. Names and ratings from the French speakers are available in Appendix A, available in the supplemental materials. The results show that most of the norms are comparable across linguistic groups and also that the ratings given are correlated across linguistic groups. The only significant group differences were found in viewpoint agreement and visual complexity. Overall, there was good concordance between the norms collected from French and English native speakers living in the same cultural setting.     

Religion,Religious Tradition,and Nationalism: Jewish Revival in Poland and “Religious Heritage” in Québec

This article uses and develops Martin Riesebrodt's distinction between religion and religious tradition to shed light on the making of various articulations of religious identities and political projects. Based on extensive research on the Polish and Québécois cases, I show how social and state actors in these societies reactivate past religious traditions to respond to current social transformations and articulate societal projects and advance political agendas in the present. In both cases, religion and religious tradition are juxtaposed to articulate new national identities or fortify older ones, and to respond more specifically to the challenges posed by “pluralism.” I suggest that sociologists who work at the intersection of religion and politics can contribute to our understanding of the various registers through which religion, religious action, and religious tradition are rendered meaningful to social actors, used for different goals (religious and not) and transformed in the process.     

What Does the Alliance Predict in Group Interventions for Early Psychosis?

The therapeutic alliance is considered an essential component of any clinical or psychological intervention. The therapeutic alliance can however change over time, and therefore it is relevant to determine if the alliance and its variations are related to clinical outcomes. The present study had three objectives: (1) determine the impact of the alliance measured by the client and the therapist, on clinical and psychosocial outcomes of individuals with early psychosis receiving group interventions; (2) measure the concordance between the client and the therapists’ ratings of the alliance; and (3) determine the best predictor of the client’s alliance in our sample. A total of 36 individuals with early psychosis who participated in group interventions for symptom management answered the WAI three times, and so did the group therapists. Outcomes included measures of insight, symptoms (total, positive and negative), and self-esteem. Attendance and group participation were also measured. Results suggest that the overall client’s alliance predicted total symptoms and self-esteem at post-therapy, whereas both clients’ and therapists’ ratings predicted group attendance and participation. Greater variations in the alliance overtime for the clients were somewhat linked to worse negative symptoms at post-therapy. Alliance ratings were generally high and fairly concordant between therapists and clients. Only the baseline measure of capacity for attachment, predicted the client’s overall alliance scores. Clinical implications are discussed.