The origin of language: A scientific approach to the study of man

The Enlightenment regarded language as one of the most significant achievements of man. Consequently inquiries into the origin and development of language play a central role in eighteenth-century moral philosophy. This new science of man consciously adopts the method of analysis and synthesis used in the natural sciences of the time. In moral philosophy, analysis corresponds to the search for the basic principles of human nature. Synthesis is identified with the attempt to interpret all artificial achievements of man (arts, sciences and institutions) as the effect of these principles and of man's physical and social environment - an attempt known as theoretical history. The type of explanation envisaged by theoretical historians is based on the principle of causality. It consists in a genetic reconstruction of the social phenomenon under investigation. Inquiries into the origin of language follow this pattern of explanation. They form part of theoretical history and thus represent a major aspect of the eighteenth-century scientific study of man.     

Differential indications for desipramine--results of a controlled multiclinical study]

The antidepressants desipramine and imipramine were compared within the framework of a multiclinical study performed under the conditions of a controlled clinical experiment. There has been found a time-different remission of affective symptoms, which was not detectable for the inhibition of drive. The tachythymoleptic action of desipramine is discussed with reference to these results. Evaluation of the possibility of controlling affects shows different ranges of activity of desipramine and imipramine, with desipramine influencing especially negative psychoenergetic symptoms in the area of drives and emotions and imipramine, restrictive symptoms in addition to differential phenomena of the psychomotor expression.     

Behavioral profiles of children with different levels of achievement

This study examines the relative importance of three behavioral dimensions to reading and mathematics achievement of elementary school children. Previous research on the dimensions which characterize the school behavior of children has shown that these dimensions can be understood as reflecting (a) an adaptation or learning problems dimension, (b) an interpersonal or a social problem dimension, and (c) an intrapersonal or personal adjustment dimension. Scores for each dimension were derived from a cluster analysis of the Pupil Behavior Rating Scale. Based on results of the cluster analysis, subjects were assigned to 12 behavioral typology groups. Analysis of variance showed that behavior typologies were related to both reading and mathematics achievement test scores. Post hoc contrasts revealed that levels of reading achievement are associated primarily with behaviors defined by attributes of the adaptation dimension, and that differences in measures of interpersonal and interpersonal dimensions do not contribute appreciably to group differences in reading and mathematics achievement.     

The treatment of epilepsies with Convulsofin

The testing of Convulsofin carried out in 220 patients at 14 clinics over a period of six months confirms the international experience gained with valproic acid and sodium valproinate. The main field of application of Convulsofin according to the experience gained will again be the treatment of fits in generalised primary epilepsy for which it permits to carry out a monotherapy to a remarkable extent. The favourable effect of the preparation in photosensitivity could be confirmed. Also in generalised secondary epilepsy and in fits of partial epilepsy. Convulsofin is partly effective, so that it can recommended as a co-medication in the treatment of therapy-resistant forms of these epilepsies which are difficult to treat. Decrease in thrombocytes, transient increase in serum transaminases, gastrointestinal disorders, loss of hair and undesired increases in body-weight were the more frequently occurring side-effects.     

Glutamate as a transmitter in the CNS and its presumed significance in the pathogenesis of cerebral seizure forms--recent aspects

Glutamate is believed to be quantitatively the most outstanding of the excitatory transmitters in the CNS. Certain conformationally related analogues, e. g. kainate, N-methyl-D-aspartate, ibotenate, and homocysteate, act as glutamate agonists. The local or systemic administration of these "excitotoxic" compounds induces epileptiform activity pointing out new and deeper insights into the epileptic process. Additionally, the glutamate transmitter hypothesis is expected to give a chance of a causal comprehension for choreatic processes as well as for the mode of action of anticonvulsant and antispastic agents.     

The sociodynamogram--a contribution to the objectivization of group process

Two simple sociometric techniques for practical use are described which are derived from the data given in the sociogram. Compared with the conventional sociogram, the group rank score we use everyday therapy has the advantage that it can be published. It permits members of the group to better identify the social situations which cause specific psychic impulses. The sociogram is reserved for the therapist. In our opinion the sociodynamogram has certain advantages over both methods because it provides an insight into spheres which are inaccessible in the sociogram and group rank score.