非小细胞肺癌靶向药物治疗争论热点

非小细胞肺癌作为全球和我国发病率最高、死亡人数最多的恶性肿瘤,其药物治疗始终是临床肿瘤学界高度关注的焦点之一.肿瘤的药物治疗模式从单纯以细胞毒药物杀伤肿瘤逐步向调节信号传导通路转变,分子靶向药物日益成为治疗肿瘤的重要武器.回顾肺癌靶向治疗的进展,诸多问题需要解决.     

“100% of anything looks good”: The appeal of one hundred percent

People overweight certainty, even when certainty is only an illusion. A vaccine that was described as 100% effective against 70% of disease targets was preferred to one described as 70% effective against 100% of disease targets (Studies 1 and 2). The appeal of 100% extends beyond the probability attribute. In Study 2, participants preferred both of the vaccines above to normatively equivalent vaccines that were less than 100% effective toward fewer than 100% of targets. In Study 3, participants preferred a 100% discount on a cup of coffee every 10 days to other more frequent, but lower amount, discounts. This preference evaporated, however, when savings were framed as points rather than as percentage discounts. We propose that people view 100% as a salient reference point and overweight it in those domains where it cannot be exceeded (e.g., probability, discount); the overweighting is weaker in domains where 100% can be exceeded (e.g., target range, points).     

竞技运动中自我控制的逆效应

自我控制的逆效应是指在高压力下,在进行努力地自我控制的过程中产了与意愿相反的心理状态的现象。文章介绍了逆加工理论的双过程模型,评论了与竞技运动相关的动作控制、情绪控制、消极表象抑制、放松和集中注意的心理控制的逆加工效应研究,并指出竞技运动中自我控制的逆加工效应研究存在三方面的局限：缺乏生态学效度、心理控制的逆效应的测量不够客观和应对策略研究不足,未来的研究应该在这三个方面有所改进     

反语认知的神经-心理机制研究及其进展

反语是指使用与本意相反的语句表达本意的修辞形式.从脑损伤者和神经发展异常者(包括精神分裂症和孤独症患者)角度,介绍了反语认知神经心理机制的研究,评述了现有研究并指出未来研究的方向.     

电视节目质量研究述评

电视节目质量研究始于20世纪40年代,不同的国家设计了不同的指标来评价节目的质量,如欣赏指数、电视指数、享受指数、值得收看指数、兴趣指数、观众满意度等。文章概述了电视节目质量研究的历史、主要成果及研究动态,并系统介绍了最具影响力的欣赏指数调查,以及欣赏指数与电视收视率、节目类型、观众人口特征等因素之间的关系,最后对目前电视节目质量研究中的局限和不足做出分析和总结     

成人面部表情及其判断的初步探讨

本实验就Izard提出的十种基本情绪采集了成人的面部表情照片,并进行了辨认评定以及同婴儿相应面部表情的比较工作。本实验结果支持了Izard的观点,认为面部表情的发生和辨认有着客观的生物基础,同时证明成人与婴儿的面部表情之间有很大连续性,从而验证了情绪表情具有先天程序化的内在本质的假设。     

Assessing School Academic Productivity: The Case of Chicago School Reform

This paper considers the issues raised in using standardized achievement test scores for purposes of examining the academic productivity of schools. We critique some commonly used practices by urban school districts and suggest an alternative approach – the school productivity profile. This profile is based on an assessment of each school's contribution to student learning, or value-added, rather than just the overall level of student attainment. We illustrate, using 10-year achievement trend data from the Chicago Public Schools (CPS), both the problems with some commonly reported indicators of school effectiveness and the idea of a school productivity profile. While our analyses suggest broad-based improvements in student learning in many Chicago schools over the past 10 years, we also found that the current testing system is not well designed to make such judgments accurately. We conclude that extant standardized testing systems, like the ITBS used in Chicago, do not afford an accurate basis for assessing school productivity and how this might be changing over time. These results have important policy implications. As school districts seek to become more outcome oriented, they will need to invest in better testing and reporting systems in order to know whether they are making genuine progress in this regard.     

正负性情绪的自主生理反应实验研究

随机抽取２４名大学生（男女各半）观看了两段内容不同的录像片段,对观看录像时的主观体验和心率（ＨＲ）、指端脉搏容积（ＦＰＶ）的变化情况做了研究。结果表明：①实验选用的两段录像分别诱发出了正性和负性情绪．②不同情绪下的自主生理反应是不同的。正性情绪下,ＨＲ变化不显著,ＦＰＶ显著下降;负性情绪下,ＨＲ显著增加,ＦＰＶ显著下降。③不同情绪下的生理反应恢复速度没有差异,但不同生理指标的恢复速度有差异,ＨＲ的恢复速度比ＦＰＶ的快．④正性情绪下,ＨＲ和ＦＰＶ之间的相关很低;负情情绪下。两种生理指标之间里显著的负相关．⑤性别只对生理指标的基础值有影响。     

关于先发情绪体验对后发情绪过程的影响的一项实验

本实验试图探讨是否存在着一种先发体验,它的影响能在随后发生的情绪过程中表现出来。实验得到了肯定的结果。它显示为:(1)先发情绪体验若与后发情绪的性质相接近,则对后者起促进作用;若相反,则起抑制作用,(2)激起后发情绪的反应时(RT)与所发生情绪的持续时(DE)二者之间有显著的正相关。     

情绪的组织功能——关于情绪对认知操作的影响的几个实验总结

本文就(1)情绪的一般唤醒和具体情绪分化、(2)不同享乐色调情绪状态对认知操作的作用、(3)怒情绪的作用、(4)作为情绪的兴趣的作用、(5)情绪以体验形式起作用等五个问题,在总结情绪与认知操作的系列实验基础上,讨论了情绪的组织性功能;认为不同享乐色调的情绪对认知操作起着性质不同的组织作用或瓦解作用。