Factors Associated with Interest in Gene-Panel Testing and Risk Communication Preferences in Women from <Emphasis Type="Italic">BRCA1/2</Emphasis> Negative Families

Scientific advances have allowed the development of multiplex gene-panels to assess many genes simultaneously in women who have tested negative for BRCA1/2. We examined correlates of interest in testing for genes that confer modest and moderate breast cancer risk and risk communication preferences for women from BRCA negative families. Female first-degree relatives of breast cancer patients who tested negative for BRCA1/2 mutations (N = 149) completed a survey assessing multiplex genetic testing interest and risk communication preferences. Interest in testing was high (70 %) and even higher if results could guide risk-reducing behavior changes such as taking medications (79 %). Participants preferred to receive genomic risk communications from a variety of sources including: primary care physicians (83 %), genetic counselors (78 %), printed materials (71 %) and the web (60 %). Factors that were independently associated with testing interest were: perceived lifetime risk of developing cancer (odds ratio (OR) = 1.67: 95 % confidence interval (CI) 1.06–2.65) and high cancer worry (OR = 3.12: CI 1.28–7.60). Findings suggest that women from BRCA1/2 negative families are a unique population and may be primed for behavior change. Findings also provide guidance for clinicians who can help develop genomic risk communications, promote informed decision making and customize behavioral interventions.     

Treating PTSD in suicidal and self-injuring women with borderline personality disorder: development and preliminary evaluation of a Dialectical Behavior Therapy Prolonged Exposure Protocol

This study focused on the development and pilot testing of a protocol based on Prolonged Exposure (PE) that can be added to Dialectical Behavior Therapy (DBT) to treat PTSD in suicidal and self-injuring individuals with borderline personality disorder (BPD). Women with BPD, PTSD, and recent and/or imminent serious intentional self-injury (n = 13) received one year of DBT with the DBT PE Protocol, plus three months of follow-up assessment. The treatment was associated with significant reductions in PTSD, with the majority of patients no longer meeting criteria for PTSD at post-treatment (71.4% of DBT PE Protocol completers, 60.0% of the intent-to-treat sample). A minority of patients (27.3%) engaged in intentional self-injury during the study. Improvements were also found for suicidal ideation, dissociation, trauma-related guilt cognitions, shame, anxiety, depression, and social adjustment. There was no evidence that the DBT PE Protocol led to exacerbations of intentional self-injury urges or behaviors, PTSD, treatment dropout, or crisis service use. Overall, the results indicate that this integrated BPD and PTSD treatment is feasible to implement within one year of treatment, highly acceptable to patients and therapists, safe to administer, and shows promise as an effective intervention for PTSD in this complex and high-risk patient population.     

A COMPARISON OF SENSORY INTEGRATIVE AND BEHAVIORAL THERAPIES AS TREATMENT FOR PEDIATRIC FEEDING DISORDERS

We compared the effects of escape extinction (EE) plus noncontingent reinforcement (NCR) with sensory integration therapy as treatment for the feeding problems of 2 children. Results indicated that EE plus NCR was more effective in increasing acceptance, decreasing inappropriate behavior, and increasing amount consumed relative to sensory integration for both children. The results are discussed in terms of the challenges of evaluating sensory‐integration‐based treatments, and the reasons why component analyses of multicomponent treatments like sensory integration are important.     

Transgender individuals' workplace experiences: the applicability of sexual minority measures and models

The present study explored whether 3 existing measures of workplace constructs germane to the experiences of sexual minority people could be modified to improve their applicability with transgender individuals. To this end, the Workplace Heterosexist Experiences Questionnaire (WHEQ; C. R. Waldo, 1999); the Lesbian, Gay, Bisexual, and Transgendered Climate Inventory (LGBTCI; B. J. Liddle, D. A. Luzzo, A. L. Hauenstein, & K. Schuck, 2004); and the Workplace Sexual Identity Management Measure (WSIMM; M. Z. Anderson, J. M. Croteau, Y. B. Chung, & T. M. DiStefano, 2001) were modified to explicitly address the experiences of transgender individuals. Data from a sample of 263 transgender individuals were used to evaluate the psychometric properties of the modified measures. Analyses of the structures of the modified measures (Transgender Forms [TF]) suggested an alternative 2-factor structure for the WHEQ-TF, but provided support for the previously observed unidimensional structure for the LGBTCI-TF, and a slightly modified 3-factor structure for the WSIMM-TF. Cronbach's alpha reliability coefficients for scale or subscale items across the 3 measures were acceptable. Criterion-related validity was evident in theoretically consistent patterns of correlations between scores on the 3 modified measures and scores on indicators of job satisfaction and outness. These data provide preliminary support for transgender-specific versions of measures of 3 key constructs in the sexual minority vocational behavior research.     

A Critically Appreciative Valuation of Social Constructionist Contributions to Organizational Science

Modernist approaches to research in the social sciences dominate academia, including much of organization science. Discovery through reason, observation, and analysis are the quintessential modernist quests. However, this reductionist approach to essentialize the social through the usage of language, a product of culture with its inevitable entanglement with cultural ideology, values, sensibility, intelligibility, and history, is akin to capturing a moving target on shifting grounds. Positing social constructionism as an alternative, we explain it has revolutionalized the social sciences and organization science alike; offer an array of social constructionist inquiry methodologies to fuel generative possibilities for organization research; compare and contrast modernist and social constructionist organization theories, research methodologies and assumptive metaphors to accentuate the textual and dialogic potential social constructionism brings to organization science; and conclude with creative ways social constructionism can realize actionable knowledge through co-creation among communities.     

A discourse analysis of power in relation to PSYCHLOPS (Psychological outcome profiles) in the context of CBT for psychosis

Aims: Outcome measures (OMs) and routine change measurement have developed dramatically in psychological therapies over the last two decades and some therapists have expressed concerns that this, depending on how it is handled by the parties involved, can markedly affect the therapy. However, little research has investigated this. It therefore seemed timely to explore discourses of OMs drawn upon by both parties in the therapy room. Method: PSYCHLOPS (Psychological Outcome Profiles) is a client‐centred measure which offered an opportunity to explore how therapists and clients receiving CBT for psychosis talked about OMs. A useful contrast was provided by the CORE‐OM (Clinical Outcomes in Routine Evaluation‐Outcome Measure). The discourses drawn upon by clients (n=4) and therapists (n=4) were analysed, informed by a Foucaultian framework. Results: OMs were constructed as empowering or disempowering of clients, as being able to do therapeutic work of engagement and containment, and as part of the apparatus of service power, positioning therapists as relatively powerless to question their use. Discussion: It is suggested that client‐centred measures like PSYCHLOPS, although partly aligned with a recovery framework, may become part of top‐down state and service power, and there is a need for more research into the different ways in which OMs are used in therapy and the impacts on therapists, clients and their relationships.     

Distinct Facial Characteristics Differentiate Communicative Intent of Infant‐Directed Speech

Adults and infants can differentiate communicative messages using the nonlinguistic acoustic properties of infant‐directed (ID) speech. Although the distinct prosodic properties of ID speech have been explored extensively, it is currently unknown whether the visual properties of the face during ID speech similarly convey communicative intent and thus represent an additional source of social information for infants during early interactions. To examine whether the dynamic facial movement associated with ID speech confers affective information independent of the acoustic signal, adults' differentiation of the visual properties of speakers' communicative messages was examined in two experiments in which the adults rated silent videos of approving and comforting ID and neutral adult‐directed speech. In Experiment 1, adults differentiated the facial speech groups on ratings of the intended recipient and the speaker's message. In Experiment 2, an original coding scale identified facial characteristics of the speakers. Discriminant correspondence analysis revealed two factors differentiating the facial speech groups on various characteristics. Implications for perception of ID facial movements in relation to speakers' communicative intent are discussed for both typically and atypically developing infants. Copyright © 2012 John Wiley & Sons, Ltd.     

Evaluative priming of naming and semantic categorization responses revisited: a mutual facilitation explanation

The evaluative priming effect (i.e., faster target responses following evaluatively congruent compared with evaluatively incongruent primes) in nonevaluative priming tasks (such as naming or semantic categorization tasks) is considered important for the question of how evaluative connotations are represented in memory. However, the empirical evidence is rather ambiguous: Positive effects as well as null results and negatively signed effects have been found. We tested the assumption that different processes are responsible for these results. In particular, we argue that positive effects are due to target-encoding facilitation (caused by a congruent prime), while negative effects are due to prime-activation maintenance (caused by a congruent target) and subsequent response conflict. In 4 experiments, we used a negative prime-target stimulus-onset asynchrony (SOA) to minimize target-encoding facilitation and maximize prime maintenance. In a naming task (Experiment 1), we found a negatively signed evaluative priming effect if prime and target competed for naming responses. In a semantic categorization task (i.e., person vs. animal; Experiments 2 and 3), response conflicts between prime and target were significantly larger in case of evaluative congruence compared with incongruence. These results corroborate the theory that a prime has more potential to interfere with the target response if its activation is maintained by an evaluatively congruent target. Experiment 4a/b indicated valence specificity of the effect. Implications for the memory representation of valence are discussed.     

Number of books at home as an indicator of socioeconomic status: Examining its extensions and their incremental validity for academic achievement

Social Psychology of Education - The present study investigates the incremental validity of the traditional books-at-home measure and selected extensions (i.e., number of children’s books and...