Recommended Regulation of Common Drugs: The Relative Influence of Facts vs. Labels

The present study examined the hypothesis that individuals are more influenced by a drug name than by the side effects associated with that drug when making recommendations regarding regulation. Subjects recommended the amount of regulation that should exist for eight drugs ranging from aspirin to LSD. One third of the subjects were asked to make recommendations based only on the drug name. Another third made recommendations based only on the facts associated with the drugs (i.e., side effects, symptoms). A final third made recommendations based on both facts and the drug name. Results indicated that, when given only the facts, subjects' recommendations deviated greatly from the actual regulation of the drugs but that the facts were ignored if subjects knew the name of the drug. These results suggest that critical information may be ignored when decisions are made about drug regulation. The implications for self-regulated drug use are discussed.     

Clinical trial of contemnol tablets (lithium retard Spofa)

A report on the clinical testing of the lithium-retard medicament Contemnol (Spofa). It details the way lithium-retard treatment is objectively and subjectively superior to the earlier and still current general lithium treatment.     

Status of perfusion scintigraphy in the diagnostic strategy in cerebrovascular disorders and space-occupying lesions

The results of an evaluation of the perfusion scintigraphy findings of 350 hospitalised neurological patients and 55 more strictly selected neurosurgical patients with cerebrovascular complaints, revealed an accuraty of 83%, a sensitivity of 89%, and a specificity of 83%. The selection of the patients had no influence on the results as a whole. Compared with contrast-medium angiography, incorrect diagnosis must be expected in 17% of the cases. This includes erroneous negative findings in 10% of the cases. Grounds for misinterpretations are suggested, and the biological and methodological limitations of the method are set forth.     

Arthur Kronfeld (1886-1941)--a psychiatrist in the service of psychotherapy

The psychotherapeutic life-work of psychiatrist Arthur Kronfeld has almost fallen into oblivion. Against the background of the 100th anniversary of his birth the author traces Kronfeld's psychotherapeutic career, pointing out his activity at the Berliner "Institute of Sexual Research" under Magnus Hirschfeld, and his psychotherapeutic concept--the psychagogic guidance of the patient--and its connection with the individual psychology of Alfred Adler. Kronfeld translated his theoretical positions into activities directed towards socialization and the teachability of psychotherapy which are still worthy of note by those engaged in the field.     

Results of neurophysiologic studies in ophthalmic migraine

The influence in 8 of our patients with ophthalmic migraine of photic driving with sine-like flashing lights on EEG background activity was checked and the visually evoked potentials following the application of diffused simple light stimuli were analyzed using the recovery cycle technique. The results indicate a slightly increased tonic activity of the structures of the mesencephalic formatio reticularis, such as may be produced by slight functional disturbances. Some vegetative secondary symptoms of migraine attacks and some of the changes in EEG observed in patients with ophthalmic migraine are explicable by such an abnormality.     

Behavior of visual evoked potentials (pattern reversal VECP) in smokers

Twenty six clinically healthy smokers were studied with transient pattern visual-evoked potentials. In comparison with a sample of "normal" subjects we found a difference of some parameters (P less than 0.05): the P2-latency and the interocular difference of latency on average were 6-7 ms respectively 2 ms larger. Thirteen subjects have had a prolonged P2-latency (P less than 0.05) and/or a difference in interocular latencies larger than 5 ms. These findings may suggest on subclinical disturbances of visual system and indicators of an special sensitivity of that person. The findings are possibly related to tobacco-alcohol amblyopia.