表观遗传修饰在应激诱发抑郁症中的作用

应激可以对个体的生理和行为产生负面影响, 甚至导致抑郁症, 但病因机制尚不清楚。近年来许多研究发现应激导致的表观遗传修饰变化影响抑郁症的发生。表观遗传是指DNA序列不发生变化, 但基因表达却发生了可遗传的改变。应激引起的HPA轴、单胺类递质、BDNF三个方面的表观遗传修饰的变化, 在抑郁症发生中发挥重要作用。最后提出了目前表观遗传机制研究的局限性和未来研究热点。     

Construct validity of the relationship profile test: impact of gender, gender role, and gender role stereotype

Research supports the construct validity of the Relationship Profile Test (RPT; Bornstein & Languirand, 2003), a 30-item, self-report measure of destructive overdependence (DO), dysfunctional detachment (DD), and healthy dependency. In this investigation, we assessed the relationships of gender, gender role, and gender role stereotype ratings to RPT subscale scores. In Study 1, we replicated earlier patterns of gender differences in RPT scores, assessed cross-sample consistency in gender difference effect sizes, and provided preliminary nonclinical norms for the RPT subscales. Study 2 showed that--as expected--DO items are perceived as stereotypically feminine, whereas DD items are perceived as stereotypically masculine. In Study 3, we examined the relationships of RPT subscale scores to masculinity, femininity, and androgyny scores. We discuss the theoretical, empirical, and clinical implications of these findings.     

微山湖区儿童智力状况分析

本文依据环境与儿童智力发展关系的理论对微山湖区船、陆两地生活的2318名5～16岁儿童少年进行了智力状况调查。并对其中298名儿童进行了较详细的影响因素调查,发现生长、生活在陆地儿童的智商明显高于生长、生活在船上的儿童,又一次证实了生活环境对儿童智力发展有直接影响.     

社区服刑人员心理健康状况调查

以探讨社区服刑人员的心理特点为目的,以康健街道社区服刑人员为范围,采用艾森克人格问卷(EPQ)及SCL-90症状自评量表对社区服刑人员的人格、心理健康方面进行调查。结果发现社区服刑人员在总体上虽基本属于正常人群在其人格特征仍与罪犯人群所特有的特点具有少量共性;其心理健康也普遍存在一定问题;同时,证明了社区服刑人员的人格与心理健康有一定的联系,其结果可以在今后的社区心理矫正工作中加以关注和应用。     

医学职业显规则何以不再“败走麦城”

近些年来,医学职业显规则接连受挫,医学职业生态呈现非常态甚至反常态。其根本原因在于,医学职业显规则与潜规则二者并存且此消彼长。职业规则是职业精神的核心。若要真正颠覆医学职业潜规则,让医学职业显规则回归医学职业生活,从而恢复或重构医学职业精神,就必须克服现存的医学职业显规则的致命性缺欠,进行自身优化,即强化自己的权威性、情境性与实用性。     

Evaluation of tablet computers for visual function assessment

Recent advances in technology and the increased use of tablet computers for mobile health applications such as vision testing necessitate an understanding of the behavior of the displays of such devices, to facilitate the reproduction of existing or the development of new vision assessment tests. The purpose of this study was to investigate the physical characteristics of one model of tablet computer (iPad mini Retina display) with regard to display consistency across a set of devices (15) and their potential application as clinical vision assessment tools. Once the tablet computer was switched on, it required about 13 min to reach luminance stability, while chromaticity remained constant. The luminance output of the device remained stable until a battery level of 5%. Luminance varied from center to peripheral locations of the display and with viewing angle, whereas the chromaticity did not vary. A minimal (1%) variation in luminance was observed due to temperature, and once again chromaticity remained constant. Also, these devices showed good temporal stability of luminance and chromaticity. All 15 tablet computers showed gamma functions approximating the standard gamma (2.20) and showed similar color gamut sizes, except for the blue primary, which displayed minimal variations. The physical characteristics across the 15 devices were similar and are known, thereby facilitating the use of this model of tablet computer as visual stimulus displays.     

新手-熟手-专家型教师成就目标定向与人格特征的研究

本研究采用量表法考察三种类型教师成就目标定向与人格特征的特点。结果表明 ,与普通成人相比 ,我国中学教师比较外倾 ,精神质水平更高。三种类型教师在任务目标上存在显著性差异 ,新手型教师的任务目标水平显著低于熟手型教师 ;而在成绩目标上 ,不存在显著性差异。新手型教师在精神质维度上与熟手型教师存在显著性差异 ,其精神质水平显著低于熟手型教师 ,熟手型教师在神经质维度上与专家型教师存在显著性差异 ,其神经质水平显著低于专家型教师 ,神经质水平高是专家型教师典型的人格特征。     

以公天下大义正家天下之法——论中唐《春秋》学的王道论述及其时代意义

在中唐至北宋的儒道复兴运动中,追求合理人间秩序的“外王”之学实与“内圣”之学并行而交叉,自中唐兴起而于北宋中叶大盛的《春秋》学颇能凸显这一思潮线索。本文着重阐发中唐《春秋》学倡明“王道”之要旨及其相关论述,指出,中唐《春秋》学抉发西汉公羊学“天下为公”的微言,于大变动的历史时机重新澄清并确立“大一统”皇权专制的政治宪纲;开始探讨在新的历史条件下士人进行政治实践的思想与行为准则即所谓“时中之道”,以树立新的君子人格;又根据“王道”精神提出振兴唐朝、重建中央集权的具体政治纲领,其“尊王”义恰恰构成对唐皇朝强化中央权威的现实政治路线的批判。中唐《春秋》学所开启的这一“原道”之路,在“大一统”秩序重建并巩固的北宋时代得到回应与延续。     

试论20世纪90年代日本媒介的中国框架

本文将采用框架分析法对日本朝日新闻有关1996年台湾海峡军事]习,和2000年朱钅容基总理访日的报道进行个案分析,从中了解其新闻框架,并简单剖析新闻框架形成的原因和背景。     

Self-esteem Among Chinese Cohorts: Its Temporal Trend and Its Relationships with Socioecological Factors, 1993–2016

Self-esteem affects individuals in a variety of psychological processes substantially and extensively. While an increase in self-esteem over time was observed in the USA, different patterns of temporal change in self-esteem were observed in other societies. We analysed the responses (n = 305 229) collected between 1993 and 2016 from 609 articles to examine the patterns of temporal change in self-esteem in China and its relations with socioecological conditions. Additionally, we explored the patterns in different groups, including secondary school students (158 samples; n = 97 751), college students (427 samples; n = 153 474), and community participants (232 samples; n = 54 004). Some major findings were noted: (i) overall, the level of self-esteem increased over time. However, we also found a significant curvilinear trend in self-esteem with a decline followed by a recent increase; (ii) some evidence for the relationship between socioecological factors and self-esteem was obtained; and (iii) the patterns varied in different cohort groups. Specifically, secondary school students showed a different pattern, in which their self-esteem level did not show a significant linear trend and was not correlated with the examined socioecological factors. The implications on the theories for the relationship between personality characteristics and socioecological conditions were discussed.