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81.
Reconsolidation is the process by which previously consolidated memories are stabilized after retrieval. Several lines of evidence indicate that glucocorticoids modulate distinct phases of learning and memory. These effects are considered to be mediated by mineralocorticoid receptors and glucocorticoid receptors (GRs), which display a high concentration and distinct distribution in the hippocampus. The role of glucocorticoid system in fear memory reconsolidation is the subject of some controversy. Moreover, we found no studies that assessed the role of hippocampal GRs in fear memory reconsolidation. Here, we investigated the effect of GR blockade on fear memory reconsolidation in rats. Rats were trained and tested in an inhibitory avoidance task. Intrahippocampal or systemic administration of the GR antagonist RU38486 immediately following memory reactivation produced a deficit in post-retrieval long-term memory that persisted over test sessions, and memory did not re-emerge following a footshock reminder. These results indicate that hippocampal GRs are required for reconsolidation of fear-based memory.  相似文献   
82.
Currently, there is no standard self-report measure of psychopathy in community-dwelling samples that parallels the most commonly used measure of psychopathy in forensic and clinical samples, the Psychopathy Checklist. A promising instrument is the Self-Report Psychopathy scale (SRP), which was derived from the original version the Psychopathy Checklist. The most recent version of the SRP (SRP-III; D. L. Paulhus, C. S. Neumann, & R. D. Hare, in press) has shown good convergent and discriminate validity and a factor structure similar to the current version of the Psychopathy Checklist (PCL-R; R. D. Hare, 1991, 2003). The analyses in the current study further investigated the viability of the SRP-III as a PCL-R-analogous measure of psychopathy in nonforensic and nonclinical samples by extending the validation process to a community sample. Using confirmatory factor analyses and logistic regressions, the results revealed that a four-factor oblique model for the SRP-III was most tenable, congruent with the PCL-R factor structure of psychopathy and previous research in which the SRP-III was administered to a student sample.  相似文献   
83.
There is increasing emphasis internationally on the use of parenting programmes to support the development of appropriate social behaviour in children. However, in such programmes diversity is often ignored. Research into the parenting styles and practices (dimensions) of different ethnic groups is needed in order to investigate the applicability of universal programmes, to guide their design and implementation in the future. Thirty‐four British Pakistani and 34 British White mothers of primary aged children, comprising equal numbers of males and females, completed English or Urdu versions of the Parental Dimensions Inventory—Short Version (PDI‐S), (Power, Int. J. Behav. Dev. 67 : 302–313) and a child behavioural screening instrument, the SDQ (Goodman, J. Child Psychol. Psychiatry 38 : 581–586). More similarities than differences between the parenting dimensions of Pakistani and White mothers were found overall. However, compared with White mothers, Pakistani mothers reported more ‘following through on discipline’ as well as ‘reminding’ as a disciplinary action. Further, Pakistani mothers reported following through on discipline more with boys than White mothers did and the more they reported inconsistent parenting, the more their children reportedly had behaviour problems. It is concluded that while these findings provide some support for the cross‐cultural applicability of generic parenting programmes, programme efficacy studies are also needed. Copyright © 2010 John Wiley & Sons, Ltd.  相似文献   
84.
A tableau is a refutation-based decision procedure for a related logic, and is among the most popular proof procedures for modal logics. In this paper, we present a labelled tableau calculus for a temporalised belief logic called TML+, which is obtained by adding a linear-time temporal logic onto a belief logic by the temporalisation method of Finger and Gabbay. We first establish the soundness and the completeness of the labelled tableau calculus based on the soundness and completeness results of its constituent logics. We then sketch a resolution-type proof procedure that complements the tableau calculus and also propose a model checking algorithm for TML+ based on the recent results for model checking procedures for temporalised logics. TML+ is suitable for formalising trust and agent beliefs and reasoning about their evolution for agent-based systems. Based on the logic TML+, the proposed labelled tableau calculus could be used for analysis, design and verification of agent-based systems operating in dynamic environments.  相似文献   
85.
One consequence of experiencing flavour — the combination of taste, smell and somatosensation that occurs during ingestion — is that it can result in perceptual changes for the odour component, when this is later smelled alone. One such change is the acquisition of taste-like properties, but whether odours can also acquire somatosensory-like qualities is largely unknown. Participants here were exposed to one odour sampled in a viscous solution, another sampled in a sweet/viscous solution, and a further odour sampled in water. The odour sampled in the sweet/viscous solution was, when later sniffed alone, judged to smell thicker and sweeter, than the other two odours. Similarly, when the sweet/viscous paired odour was added to a viscous solution, the combination was judged as more viscous, than the other two odours — and sweeter when added to a sweet solution. This experiment suggests that odours can acquire tactile-like somatosensory qualities and this may best occur when a taste is present during learning. Recent work indicates that tastes may be superior to somatosensory stimuli alone in promoting flavour binding, a seeming precondition for this type of learning.  相似文献   
86.
Ali N  Chater N  Oaksford M 《Cognition》2011,119(3):403-418
In this paper, two experiments are reported investigating the nature of the cognitive representations underlying causal conditional reasoning performance. The predictions of causal and logical interpretations of the conditional diverge sharply when inferences involving pairs of conditionals—such as if P1then Q and if P2then Q—are considered. From a causal perspective, the causal direction of these conditionals is critical: are the Picauses of Q; or symptoms caused byQ. The rich variety of inference patterns can naturally be modelled by Bayesian networks. A pair of causal conditionals where Q is an effect corresponds to a “collider” structure where the two causes (Pi) converge on a common effect. In contrast, a pair of causal conditionals where Q is a cause corresponds to a network where two effects (Pi) diverge from a common cause. Very different predictions are made by fully explicit or initial mental models interpretations. These predictions were tested in two experiments, each of which yielded data most consistent with causal model theory, rather than with mental models.  相似文献   
87.
Two studies examined the relationship between the ability to access specific autobiographical material in memory and presence/symptoms of posttraumatic stress. In Study 1, a sample of refugees with a diagnosis of posttraumatic stress disorder (PTSD) completed the Autobiographical Memory Test (AMT) in which they had to generate specific episodic autobiographical memories in response to emotion-related cue words. Results showed that reduced specificity of memories on the AMT was associated with an increased frequency of trauma-related flashbacks but with reduced use of effortful avoidance to deal with trauma-related intrusions in the day-to-day. Study 2 examined retrieval of semantic autobiographical information from previous lifetime periods in groups of cancer survivors with posttraumatic stress and healthy controls. The cancer survivors were able to generate fewer specific semantic details about the personal past compared to the controls. The more symptomatic survivors showed the greatest memory impairment. The data from both studies are discussed in terms of compromised access to specific autobiographical material in distressed trauma survivors reflecting a process of affect regulation.  相似文献   
88.
Population based genetic counseling that promotes public health goals is an appropriate health care service. The genetic counseling center in Shiraz, southern Iran serves most of the clients in the region. During a 4-year period, 2,686 couples presented for genetic counseling. Data files revealed that 85% had consanguineous relationships (1.5% double first cousin, 74% first cousin, 8% second cousin, 1.5% beyond second cousin). Most prevalent reasons for referral were premarital counseling (80%), with 89% consanguinity, followed by preconception (12%), postnatal (7%), and prenatal counseling (1%). The most common abnormalities in probands or relatives were intellectual and developmental disabilities, hearing loss/impairment, and neuromuscular dystrophies. Family history of medical problem(s) and/or consanguinity was the main indication for referral in nearly every family. Premarital consanguinity poses unique challenges and opportunities. There is considerable opportunity for genetic counseling and education for couples in this population. The tradition of consanguinity, which is likely to persist in Iran, requires multidisciplinary agreement regarding the appropriate process of genetic counseling. Effective genetic counseling in Iran hinges on inclusion of data from genetic counseling services in national genomic and epidemiologic research programs.  相似文献   
89.
The present research was conducted in the Netherlands and used an experimental design to examine the endorsement of minority rights among Turkish and Kurdish participants in two framed, national contexts: the Netherlands and Turkey. In the Dutch context, each group is a minority, whereas in the Turkish context the Kurds are an oppressed national minority and the Turks are the national majority. The results showed that the Turks were less in favor of minority rights in the Turkish context than in the Dutch context, whereas the Kurds were more in favor of minority rights in the Turkish than in the Dutch context. In addition, the endorsement of minority rights was related to beliefs about majority rule, state unity, and ingroup identification, as well as to cultural diversity and perceived pervasive discrimination. The associations with the former three measures differed between the two groups and the two national contexts, whereas the latter two measures had main effects on the endorsement of minority rights.  相似文献   
90.
Plato argues in Republic IX that people are often mistaken about their own pleasures and pains. One of the mistakes he focuses on is judging that an experience of ours is pleasant when, in fact, it is not. The view that such a mistake is possible is an unpopular one, and scholars have generally been dismissive of Plato's position. Thus Urmson argues not only that this position is deeply flawed, but also that it results from a confusion on Plato's part. In this paper, I show that Urmson's criticism is misguided. I then defend Plato against the idea that it is impossible for someone to make the mistake in question. In doing so, I bring out details in Plato's text and show that his account of the phenomenology involved in making this mistake is far more sophisticated than has so far been recognized.  相似文献   
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