Nanotechnological Icons

Modern microscopes create a capacity to see and act at the scale where unassisted human senses are powerless. Images of nanoscale phenomena represent a world that effectively intervenes in human life while remaining distant and ineffable. This combination of an unbridgeable distance between man and technology with a real power of the latter over the human condition is characteristic, not only of nanotechnology, but also of the theology of sacred icons that mediate in the knowledge of divine reality. We draw an anthropological analogy between nanotechnological images and sacred icons, and we employ it to analyze the functioning of such images in society. The questions that we study include: a) the art of mediation in representing the ineffable and its necessity; b) the effects provoked by such images; c) primitive comprehension of nanoscale images. This work has repercussions for a wide variety of disciplinary accounts and practices, from the anthropologist and the philosopher to the laboratory scientist, the art critic, and the engineer who conceives and designs nanoscale instruments.     

A simple neural network model of the hippocampus suggesting its pathfinding role in episodic memory retrieval

The goal of this work is to extend the theoretical understanding of the relationship between hippocampal spatial and memory functions to the level of neurophysiological mechanisms underlying spatial navigation and episodic memory retrieval. The proposed unifying theory describes both phenomena within a unique framework, as based on one and the same pathfinding function of the hippocampus. We propose a mechanism of reconstruction of the context of experience involving a search for a nearly shortest path in the space of remembered contexts. To analyze this concept in detail, we define a simple connectionist model consistent with available rodent and human neurophysiological data. Numerical study of the model begins with the spatial domain as a simple analogy for more complex phenomena. It is demonstrated how a nearly shortest path is quickly found in a familiar environment. We prove numerically that associative learning during sharp waves can account for the necessary properties of hippocampal place cells. Computational study of the model is extended to other cognitive paradigms, with the main focus on episodic memory retrieval. We show that the ability to find a correct path may be vital for successful retrieval. The model robustly exhibits the pathfinding capacity within a wide range of several factors, including its memory load (up to 30,000 abstract contexts), the number of episodes that become associated with potential target contexts, and the level of dynamical noise. We offer several testable critical predictions in both spatial and memory domains to validate the theory. Our results suggest that (1) the pathfinding function of the hippocampus, in addition to its associative and memory indexing functions, may be vital for retrieval of certain episodic memories, and (2) the hippocampal spatial navigation function could be a precursor of its memory function.     

Attention and cognitive control: unfolding the dichotic listening story

In this article we present a theoretical approach to cognitive control and attention modulation, as well as review studies related to such a view, using an auditory task based on dichotic presentations of simple consonant-vowel syllables. The reviewed work comes out of joint research efforts by the 'Attention-node' at the 'Nordic Center of Excellence in Cognitive Control'. We suggest a new way of defining degrees of cognitive control based on systematically varying the stimulus intensity of the right or left ear dichotic stimulus, thus parametrically varying the degree of stimulus interference and conflict when assessing the amount of cognitive control necessary to resolve the interference. We first present an overview and review of previous studies using the so-called "forced-attention" dichotic listening paradigm. We then present behavioral and neuroimaging data to explore the suggested cognitive control model, with examples from normal adults, clinical and special ability groups.     

What Valentine Announcements Reveal about the Romantic Emotions of Men and Women

Gender differences in the expression of romantic emotions were investigated by analyzing the content of 300 Valentine’s Day announcements. The emotions studied were love, praise, commitment, and fidelity, as expressed by dating and married individuals. Women emphasized love and fidelity relatively more than men did; men emphasized praise and commitment relatively more than women did. Relationship status influenced the gender differences; most interesting is that dating men expressed commitment, but not fidelity. Social-cultural and evolutionary perspectives are considered in the interpretation of the findings.     

Der Streit der russischen Marxisten um Kants Ethik

At the beginning of 20th century, there was a problem of establishing which version of the association of Kant’s and Marx’s ideas is correct. If some Legal Marxists more or less combined Kant and Marx, most Russian Social Democrats, especially Bolsheviks, were against such an association. Under the influence of G. V. Plekhanov, Russian Marxists announced a sharply critical attitude toward Kant’s philosophy. This position was reinforced by Russian philosophers, poets, and slavophiles who accused Kant of being militarist. During the World War I, both tendencies faced each other. Plekhanov’s desperate appeal to ?the simple laws or morals and justice” and Kant’s “Critique of Practical Reason”, which was supported by L. I. Axelrod, failed. It was rejected by the majority of Marxists both during the World War I and after the triumph of the 1917 October Revolution.     

The effectiveness of mathematics in physics of the unknown

Synthese - If physics is a science that unveils the fundamental laws of nature, then the appearance of mathematical concepts in its language can be surprising or even mysterious. This was Eugene...     

Isatin: role in stress and anxiety

(Indoledione 2,3) isatin is an endogenous indole found both in mammalian brain and peripheral tissues. Isatin concentration in blood can exceed 1 microM and tissue concentrations vary from < 0.1 to 10 microM. Its level in the brain and periphery is increased by stress. Isatin has a wide spectrum of behavioural and metabolic effects. It is anxiogenic at lower doses and sedative at higher doses. Its most potent known in vitro actions are as an antagonist of atrial natriuretic peptide (ANP) function and NO signaling. In this review, we discuss isatin and stress in animal models, the few human studies, and also what it is known to date about the molecular mechanisms of its action. We suggest the possibility that isatin and its analogues may be interesting new pharmacological agents; Isatin antagonists may be anxiolytic, and isatin agonists may activate the HPA axis.     

The Origins of Walter Benjamin's Concept of Philosophical Critique

Focusing on Walter Benjamin's earliest pieces dedicated to school reform and the student movement, this article traces the basic critical approaches informing his mature thought back to his struggle to critically implement and transform the theory of concept formation and value presentation developed by his Freiburg teacher, Heinrich Rickert. It begins with an account of Rickert's work, specifically of the concept of Darstellung (presentation) and its central role in Rickert's postmetaphysical theory of historical research (which he characterizes as exclusively concerned with the Kantian quid juris). It shows that Rickert develops a speculative but practical theory of value recognition, which nevertheless leaves the status of value itself undetermined. Contra Rickert, Benjamin returns to the ignored quid facti, or origin of value, and shows that a metacritical, postmetaphysical approach such as Rickert's ultimately limits possible experience rather than grounding it. This basic insight, it is argued, is the cornerstone of Benjamin's concept of critique.