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71.
In April 2006, the Scottish Liver Transplant Unit in Edinburgh became the first NHS transplant unit in the UK to offer adult-to-adult living donor liver transplantation (LDLT). This procedure allows a healthy individual to donate part of their liver to someone with end-stage liver disease. With donations from the deceased in short supply, this procedure has the capacity to save lives. The aim of this study was to explore the attitudes of the general public and general practitioners (GPs) towards LDLT, before its implementation. A total of 1041 members of the Scottish general public and 155 GPs working in Scotland completed a short questionnaire devised for this study. The majority of participants supported the option of LDLT, but frequency counts showed that only 34% of the general public wish to donate their organs following death compared to 85% of GPs. With regards to an acceptable risk of death before volunteering to donate, 25% of GPs would accept a 1 in 20 risk of death, whereas 50% of the general public either could not make a decision or selected ‘No risk’. The question of how well people understand the concept of risk was again highlighted in this study.  相似文献   
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In search of a potential problem with cloning, I investigate the phenomenon of telomere shortening which is caused by cell replication; clones created from somatic cells will have shortened telomeres and therefore reach a state of senescence more rapidly. While genetic intervention might fix this problem at some point in the future, I ask whether, absent technological advances, this biological phenomenon undermines the moral permissibility of cloning.  相似文献   
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Four studies investigated a goal regulation view of anxious uncertainty threat (Gray & McNaughton, 2000) and ideological defense. Participants (N = 444) were randomly assigned to have achievement or relationship goals implicitly primed. The implicit goal primes were followed by randomly assigned achievement or relationship threats that have reliably caused generalized, reactive approach motivation and ideological defense in past research. The threats caused anxious uncertainty (Study 1), reactive approach motivation (Studies 2 and 3), and reactive ideological conviction (Study 4) only when threat-relevant goals had first been primed, but not when threat-irrelevant goals had first been primed. Reactive ideological conviction (Study 4) was eliminated if participants were given an opportunity to attribute their anxiety to a mundane source. Results support a goal regulation view of anxious uncertainty, threat, and defense with potential for integrating theories of defensive compensation.  相似文献   
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With the increasing interest in the neuroimaging of deception and its commercial application, there is a need to pay more attention to methodology. The weakness of studying deception in an experimental setting has been discussed intensively for over half a century. However, even though much effort has been put into their development, paradigms are still inadequate. The problems that bedevilled the old technology have not been eliminated by the new. Advances will only be possible if experiments are designed that take account of the intentions of the subject and the context in which these occur.  相似文献   
77.
Mothers' distress is a correlate of their children's elevated behaviour problems and symptoms. Parenting practices have been shown to mediate these associations, but few studies have observed parenting or focused on parents at risk of child abuse. In this study of 269 high‐risk mothers and their young children (M = 4.2 years), structural equation modelling was used to test associations between mothers' distress and child externalizing and internalizing symptoms. Associations were expected to be partly indirect via mothers' observed low sensitivity, and child gender was expected to moderate associations. Also, mothers' child abuse risk was examined as a unique correlate of sensitivity and children's symptoms, and a moderator of associations of distress with sensitivity and symptoms. Associations showed a pattern of gender‐moderated mediation with the link between mothers' distress and internalizing mostly direct for boys, and equally direct and indirect via sensitivity for girls. The association of mothers' distress with externalizing was mostly direct for boys and girls. Mothers' child abuse risk was not uniquely associated with sensitivity or symptoms and did not moderate any associations. There were no differences in model paths between mothers referred from child welfare/mental health compared with other sources or self‐referred. Copyright © 2013 John Wiley & Sons, Ltd.  相似文献   
78.
Necessary and sufficient conditions for the symmetry of the limiting distributions of response probabilities are derived for the Bush and Mosteller two experimenter-controlled events learning model [Bush and Mosteller, 1955].  相似文献   
79.
This research was designed to incorporate the test anxiety (TA) construct into the hierarchical model of approach and avoidance achievement motivation. Hypotheses regarding state and trait TA were tested in 2 studies, and the results provided strong support for the predictions. State TA (specifically, worry) was documented as a mediator of the negative relationship between performance-avoidance goals and exam performance. The positive relationship between performance-approach goals and exam performance was shown to be independent of TA processes. A series of analyses documented the conceptual and functional convergence of trait TA and fear of failure (FOF), and further validation of the proposed integration was obtained by testing trait TA/FOF and state TA together in the same model. Mastery goals were positively and performance-avoidance goals negatively related to long-term retention.  相似文献   
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This paper considers the possible contribution of Quality of Life methods in international development policy and practice. It discusses the role of theories of human needs in how public policy makers and implementors might distinguish between ‘needs’ and ‘wants’. There is a good case for extending theories of human need to encompass social and psychological needs, but when we do so the ability of theory to distinguish between ‘needs’ and ‘wants’ begins to evaporate. Rather, by virtue of the core relationship between needs denial and harm, it is argued that a theory of human need can provide a framework for reasoning about what constitute needs. Empirical quality of life data can then assist policy makers to identify what constitute needs satisfiers in particular societal and cultural contexts. They also can provide important information to enable processes of public reasoning about the relative societal importance of different needs claims. The paper uses data generated through the application of two Quality of Life methods in Southern and Northeast Thailand, which were employed as part of a comprehensive study of the social and cultural construction of wellbeing in developing countries, to illustrate its arguments. The paper concludes that if routinely incorporated into local policy process, such quality of life methods have a possible contribution to make to effective democratic governance for development.  相似文献   
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