Transfer of spatial behavior between different environments: implications for theories of spatial learning and for the role of the hippocampus in spatial learning

In 3 experiments, rats were required to find a submerged platform located in 1 corner of an arena that had 2 long and 2 short sides; they were then trained to find the platform in a new arena that also had 2 long and 2 short sides but a different overall shape. The platform in the new arena was easier to find if it was in a corner that was geometrically equivalent, rather than the mirror image, of the corner where it had previously been located. The final experiment revealed that hippocampal lesions impaired rats' ability to find the platform in these arenas. The results suggest that rats did not use the overall shape of the arena to locate the platform but relied on more local cues and that the hippocampus plays a role in navigation based on these cues.     

Prepared movements are elicited early by startle

A startle stimulus has been shown to elicit a ballistic response in a reaction time (RT) task at very short latencies without involvement of the cerebral cortex (J. Valls-Sole, J. C. Rothwell, F. Gooulard, G. Cossu, & E. Munoz, 1999). The present authors examined the nature of the startle response. A simple RT task was used in which 8 participants performed arm extension movements to 3 target distances (20 degrees, 40 degrees, and 60 degrees ) in a blocked design. An unpredictable startling acoustic stimulus (124 dB) replaced the imperative stimulus in certain trials. The authors verified the presence of a startle response independent from the prepared response by observing electromyographic (EMG) activity in sternocleidomastoid and orbicularis oculi muscles. Findings indicated that when the participant was startled, the intended voluntary response was produced at significantly shorter response latencies. Furthermore, the kinematic variables of the observed response during startle trials for all 3 target distances were mostly unchanged. The EMG characteristics of the responses were not modified, indicating that the response produced was indeed the prepared and intended response.     

How lonely are gay and lesbian youth?

UCLA Loneliness Scale (8-item version) scores in a sample of 384 gay and lesbian adolescents support the hypothesis that such youths are especially vulnerable to loneliness.     

Affective, behavioral, and cognitive functioning in adolescents with multiple suicide attempts

The purpose of this study was to examine affective, behavioral, and cognitive functioning in adolescents with multiple suicide attempts. Forty-seven adolescents with a history of multiple suicide attempts (MA) were compared to 74 single suicide attempters (SA) on psychiatric diagnosis, depressive symptoms, affect regulation, self-mutilation, alcohol use, and hopelessness. Results revealed that the MA group was more likely to be diagnosed with a mood disorder, and reported more severe depressive symptoms and anger, in comparison to the SA group. Behaviorally, the MA group had higher rates of disruptive behavior disorders and higher levels of affect dysregulation and serious self-mutilation than the SA group. Further, greater levels of hopelessness were reported by the MA than the SA group. After controlling for a mood disorder diagnosis, only differences in anger, affect dysregulation, and serious self-mutilation remained significant. Overall, results suggest that treatment with adolescent suicide attempters might specifically target anger and affect dysregulation to reduce risk for future suicidal behavior.     

The ‘redefinition of death’ debate: Western concepts and western bioethics

Biomedicine is a global enterprise constructed upon the belief in the universality of scientific truths. However, despite huge scientific advances over recent decades it has not been able to formulate a specific and universal definition of death: In fact, in its attempt to redefine death, the concept of death appears to have become immersed in ever increasing vagueness and ambiguity. Even more worrisome is that bioethics, in the form of principlism, is also endeavouring to become a global enterprise by claiming neutrality. It appears that the discourse within both disciplines have similarly manipulated the boundaries of death to include the “dying”. This paper argues that the redefinition of death debate in biomedicine reveals a concept of personhood which is profoundly western in origin and which is in accordance to the concept adhered to within principlism. Biomedicine and bioethics do not appear to acknowledge the limitations of their own world view and hence lack an understanding of their applicability and appropriateness in diverse social and cultural contexts; a situation which adds credence to claims as to the hegemonic and imperialistic nature of all such global enterprises. Ms. Jones is an intensive care clinical nursing specialist. Dr. Kessel is a public health physician and medical ethicist.     

Prolegomena to a Catholic Theology of God between Heidegger and Postmodernity

New opportunities for discourse about God have arisen, along with new challenges to the mainstream Catholic theology of God. In order to take advantage of these opportunities, a truly contemporary Catholic theology of God must critically appropriate three 'events' which have affected its approach to the subject matter: (1) Heidegger's periodizing critique of ontotheology; (2) the 'contemporary' viewed as the arena of contention between modern and postmodern claims; (3) the presence of the Kingdom of God and the revelation of the nature of God in the person and work of Jesus Christ, which alter our understandings of time and being. The present essay sketches a program for an authentically Catholic response to the issues raised by these occurrences, emphasizing the Catholic commitment to incarnation and sacramentality and the necessary effort to retrieve redemptive images of God from modernity, despite the present tendency of some postmodern theologians and philosophers to dismiss aspects of the past as unusable.     

Examination of the PC-PTSD in previously deployed Air Force Medical Service personnel

This study assessed the performance of the PC-PTSD in diagnosing postdeployment posttraumatic stress disorder (PTSD) in a cohort of Air Force Medical Services personnel (N = 18,530). The prevalence of PTSD in the cohort was 5.18% based on medical record data. The area under the receiver operating characteristic curve was 0.69, indicating poor classification accuracy. Sensitivity was 47.55%, specificity was 90.68%, positive predictive value was 21.79%, and negative predictive value was 96.94%. The positive and negative likelihood ratios were 5.10 and 0.58, respectively. Several risk factors were found to be associated with a diagnosis of postdeployment PTSD: being a nurse, being enlisted in the medical service career field, being enlisted in the mental health service career field, those over age 30, being a member of the Active Duty service component, and having one’s first deployment be to Iraq. Being an officer was found to be a protective characteristic. These factors could potentially improve screening for PTSD among Air Force healthcare personnel.     

The pursuit of missing information in negotiation

A large body of research has focused on how people exchange and use information during the negotiation process. This work tends to treat information as if it all were readily available upon request. The current research investigated how delays in the pursuit of missing information can influence people’s ex-ante priorities and the final settlements they reach. Study 1 found that negotiators achieved more value on an issue after seeking missing information about that issue compared to when the same information was readily accessible. Study 2 found that the effect of searching for information on outcomes was mediated by changes in how important negotiators perceived the issue to be. Theoretical and practical implications are discussed.