BRCA1 Testing: Genetic Counseling Protocol Development and Counseling Issues

This article discusses the genetic counseling protocols which were developed and counseling issues that have arisen in the first 2 years of evaluating a large kindred with a BRCA1 mutation. The rationale for the development of the genetic counseling protocols and specific genetic counseling visual aids are presented and discussed. The protocols and counseling aids can serve as models for other programs offering cancer susceptibility testing. The observations of study counselors about study subject concerns and responses to genetic testing at the time of the pretest and posttest counseling sessions are presented.     

On Meaningfulness and Truth

We show how to construct certain L _{M, T} -type interpreted languages, with each such language containing meaningfulness and truth predicates which apply to itself. These languages are comparable in expressive power to the L _T -type, truth-theoretic languages first considered by Kripke, yet each of our L _{M, T} -type languages possesses the additional advantage that, within it, the meaninglessness of any given meaningless expression can itself be meaningfully expressed. One therefore has, for example, the object level truth (and meaningfulness) of the claim that the strengthened Liar is meaningless.     

The relative deprivation-gratification continuum and the attitudes of South Africans toward immigrants: a test of the V-curve hypothesis

It has long been established that there is a linear and positive relationship between relative deprivation and prejudice. However, a recent experiment suggests that the converse of relative deprivation, relative gratification, may also be associated with prejudice (S. Guimond & M. Dambrun, 2002). Specifically, the evidence suggests that the usual test for a linear relationship between relative deprivation-gratification and prejudice might conceal the existence of a bilinear relationship. This function, labeled the V-curve hypothesis, predicts that both relative deprivation and relative gratification are associated with higher levels of prejudice. This hypothesis was tested with a representative sample of South Africans (N=1,600). Results provide strong support for the V-curve hypothesis. Furthermore, strength of ethnic identification emerged as a partial mediator for the effect of relative gratification on prejudice.     

Journal of Counseling & Development Publication Patterns: Author and Article Characteristics From 1994 to 2009

Publication patterns of articles in the Journal of Counseling & Development from 1994 to 2009 were reviewed. Trends over time were analyzed in article content (e.g., type, content topic) and author demographic characteristics (i.e., gender, nation of domicile, and employment setting). Of particular interest because of the scientific underpinnings of the counseling profession, research articles were analyzed specifically for type of research approach, classification, methodology, sample, sample size, and statistics used.     

Transcultural wellness: An Exploratory Study

This study explored differences in wellness scores between a transcultural sample and the normative sample of the Five Factor wellness Inventory (5F‐wel; Myers & Sweeney, 2005c). Differences between the two groups were found on all scales of the 5f‐wel, with transculturals scoring higher than the normative sample. Implications for practitioners and researchers are presented for those working with transculturals. Este estudio exploró las diferencias en puntuaciones de bienestar entre una muestra transcultural y la muestra normativa de los Cinco factores del Inventario de Bienestar (5F‐wel, por sus siglas en inglés; Myers & Sweeney, 2005c). Se hallaron diferencias entre los dos grupos en todas las escalas del 5f‐wel, con las puntuaciones transculturales siendo más altas que la muestra normativa. Se presentan implicaciones para profesionales e investigadores que estén trabajando con individuos transculturales.     

Preferential processing of threatening facial expressions using the repetition blindness paradigm

Background: Neuroanatomical evidence suggests that the human brain has dedicated pathways to rapidly process threatening stimuli. This processing bias for threat was examined using the repetition blindness (RB) paradigm. RB (i.e., failure to report the second instance of an identical stimulus rapidly following the first) has been established for words, objects and faces but not, to date, facial expressions. Methods: 78 (Study 1) and 62 (Study 2) participants identified repeated and different, threatening and non-threatening emotional facial expressions in rapid serial visual presentation (RSVP) streams. Results: In Study 1, repeated facial expressions produced more RB than different expressions. RB was attenuated for threatening expressions. In Study 2, attenuation of RB for threatening expressions was replicated. Additionally, semantically related but non-identical threatening expressions reduced RB relative to non-threatening stimuli. Conclusions: These findings suggest that the threat bias is apparent in the temporal processing of facial expressions, and expands the RB paradigm by demonstrating that identical facial expressions are susceptible to the effect.     

Low Rates of African American Participation in Genetic Counseling and Testing for BRCA1/2 Mutations: Racial Disparities or Just a Difference?

Low rates of genetic counseling among African American women have generated concerns about disparities; however, to the extent that women's decisions to accept or decline counseling are consistent with their values, then lower participation may reflect preferences and not disparities. We evaluated the extent to which women were satisfied with their decision about participating in genetic counseling for BRCA1/2 mutations and identified variables that were associated significantly with satisfaction. Prospective study of decision satisfaction with 135 African American women who had a minimum 5% prior probability of having a BRCA1/2 mutation. Decision satisfaction was evaluated one month after women were offered participation in genetic counseling using a structured questionnaire. Women were satisfied with their participation decision; more than 80% reported that their decision was consistent with their family values. However, women who declined pre-test counseling had significantly lower satisfaction scores. Our findings highlight the importance ensuring that racial differences that are due to preferences and values are not misclassified as disparities in order to identify and address the root causes of disparate treatment.     

Applied Social Psychology: A Critical Theoretical Perspective

The purpose of this analysis is to review, through a critical theoretical lens, social psychology applied to work and organisations. In our reading of the applied social psychological literature four key issues emerged. These include the valorisation of a positivist epistemology, an owner/management perspective on workplace issues, a focus on intra‐psychic variables or internal mental states when accounting for organisational problems, and the ignoring of moral and ethical commitments in determining workplace research and practice. Each of these issues is then further analysed in light of insights from the field of Critical Management Studies. This alternative approach to organisational behaviour points to the ways in which applied social psychological theory and practice have the potential to disadvantage workers.     

Persistent impairments in hippocampal function following a brief series of photoperiod shifts in rats

The impact of an acute circadian disruption on learning and memory in male and female rats was examined. Circadian disruption was elicited using a brief series of photoperiod shifts. Previous research using male rats showed that acute circadian disruption during acquisition of a spatial navigation task impaired long-term retention and that chronic circadian disruption impaired acquisition of the same task. However, the long-term effects of acute circadian disruption following circadian re-entrainment and whether sex differences in response to circadian disruption exist are still unknown. For the present study, rats were trained on the standard, spatial version of the Morris water task (MWT) and a visual discrimination task developed for the eight-arm radial maze. After reaching asymptotic performance, behavioural training was terminated and the experimental group experienced a series of photoperiod shifts followed by circadian re-entrainment. Following circadian re-entrainment, the subjects were given retention tests on the MWT and visual discrimination task. Following retention testing, an extra-dimensional shift using the eight-arm radial maze was also performed. An acute episode of circadian disruption elicited via photoperiod shifts negatively impacted retention of spatial memory in male and female rats. Retention of the visual discrimination task and the ability to detect extra-dimensional shifts were not impaired. The observed impairments on the MWT indicate that hippocampal representations are susceptible to a small number of photoperiod shifts even if the association is acquired prior to rhythm manipulation and retention is assessed following rhythm stabilization. Effects were limited to a hippocampus-dependent task, indicating that impairments are specific, not global.