Mechanisms and the current state of deep brain stimulation in neuropsychiatry

Deep brain stimulation (DBS) is established as a therapy for movement disorders, and it is an investigational treatment in other neurologic conditions. DBS precisely targets neuroanatomical targets deep within the brain that are proposed to be centrally involved in the pathophysiology of some neuropsychiatric illnesses. DBS is nonablative, offering the advantages of reversibility and adjustability. This might permit therapeutic effectiveness to be enhanced or side effects to be minimized. Preclinical and clinical studies have shown effects of DBS locally, at the stimulation target, and at a distance, via actions on fibers of passage or across synapses. Although its mechanisms of action are not fully elucidated, several effects have been proposed to underlie the therapeutic effects of DBS in movement disorders, and potentially in other conditions as well. The mechanisms of action of DBS are the focus of active investigation in a number of clinical and preclinical laboratories. As in severe movement disorders, DBS may offer a degree of hope for patients with intractable neuropsychiatric illness. It is already clear that research intended to realize this potential will require a very considerable commitment of resources, energy, and time across disciplines including psychiatry, neurosurgery neurology, neuropsychology, bioengineering, and bioethics. These investigations should proceed cautiously.     

Authoritarian and aggressive attitudes in American students

In a sample of 118 college students, scores on a measure of authoritarian attitudes were associated with scores on subscales from the Buss and Perry (1992) Aggression Questionnaire.     

Behavioral problems and scholastic adjustment among Bedouin-Arab children from polygamous and monogamous marital family structures: some developmental considerations

Families in the Bedouin-Arab community in Israel are characterized by monogamous and polygamous marriages. Such diversity in family structure occurs in other parts of the world, yet scant empirical evidence exists to refute or to support the claim that polygamous family structure can be a risk factor for children's school maladjustment and negative developmental outcomes. The purpose of the current study was to test this claim. Participants were 255 3rd-grade children from the Negev Bedouin community in Israel. One hundred fifty-three children came from monogamous families that were characterized by 1 wife (i.e., 1-wife families), and 102 children came from polygamous families consisting of 2 wives (i.e., 2-wife families). Teachers completed the Teacher's Report Form of the Child Behavior Checklist (T. M. Achenback, 1991b). A series of logistic regression analyses, after adjusting for maternal education level, revealed that 2-wife children tended to have higher levels of externalizing problems in general and higher levels of attention problems in particular than did their 1-wife counterparts. Also, 2-wife children had higher rates of school absenteeism and lower levels of overall academic achievement than did 1-wife children. Implications for the Bedouin society are discussed.     

A Translation of Intuitionistic Predicate Logic into Basic Predicate Logic

Basic Predicate Logic, BQC, is a proper subsystem of Intuitionistic Predicate Logic, IQC. For every formula in the language {, , , , , , }, we associate two sequences of formulas 0,1,... and 0,1,... in the same language. We prove that for every sequent , there are natural numbers m, n, such that IQC , iff BQC n m. Some applications of this translation are mentioned.     

Sex education sources and attitudes about premarital sex of Seventh Day Adventist youth

37 Seventh Day Adventist youth were surveyed about their sex education and attitudes towards premarital sex. Analysis indicated differences between their attitudes and actual sexual behaviour. While 70% endorsed the church's prohibition on premarital sex, 54% had engaged in premarital sex.     

Critical flicker frequency under monocular and binocular conditions.

Critical flicker frequency of 40 undergraduate students, 20 men and 20 women whose mean age was 19.3 yr., was measured under monocular and binocular viewing conditions, using the Lafayette Visual Perception Control with Display Unit. Half of the subjects received monocular treatment first and binocular treatment second, and the other half received the treatments in the reversed order. A 2-min. rest was allowed between these treatments. Analysis shows that mean CFF under the monocular condition was significantly lower than that under binocular conditions. The findings were discussed in terms of visual constraint and eye strain and fatigue under the monocular viewing condition.     

Suggestions to Improve the Comprehensibility of Current Definitions of Scientific Authorship for International Authors

Science and Engineering Ethics - Much has been said about the need for improving the current definitions of scientific authorship, but an aspect that is often overlooked is how to formulate and...     

Psychological maladjustment mediates the link between remembrances of parental rejection in childhood and loneliness in adulthood: A cross-cultural comparative study

Drawing stimulus from interpersonal acceptance-rejection theory, this multicultural study examined relations between men's versus women's remembrances of maternal and paternal acceptance-rejection in childhood and their current level of loneliness, as mediated by adults' self-reported psychological maladjustment. Adults (N = 899) from five nations (Iraq, Italy, the Netherlands, Pakistan, and the United States) responded to the Adult version of the Parental Acceptance-Rejection Questionnaire-short form for mothers and fathers, the Adult version of the Personality Assessment Questionnaire-short form, and the Interpersonal Acceptance-Rejection Loneliness Scale. Adults' remembrances of maternal and paternal rejection in childhood significantly and independently predicted feelings of loneliness but remembered paternal rejection was more strongly related to these feelings than were remembrances of maternal rejection. Psychological maladjustment fully mediated the effect of remembered maternal rejection but only partially mediated the effect of remembered paternal rejection on loneliness. There were no significant differences in these results across the five countries or genders. Overall, the results suggest that adults' remembrances of parental rejection in childhood—along with the theoretically expected development of psychological maladjustment—are likely to be associated panculturally with the experience of loneliness in adulthood.     

The Effect of Spiritual Self-care Training on the Quality of Life of Mothers of Preterm Infants: A Randomized Controlled Trial

The present study was carried out with the aim of determining the effect of spiritual self-care training on the quality of life of mothers of preterm infants. This trial was carried out on 60 mothers with premature infants. Mothers were randomly divided into two intervention and control groups. Training for increasing awareness about the condition of the infants was carried out in both groups. In the intervention group, spiritual self-care training was also done. Data were completed in both groups before, immediately after, and two weeks after the intervention by using the standard WHO quality of life questionnaire. Data were analysed using statistical tests, including ANOVA and Repeated Measures. The results showed that the average quality of life of mothers under study was significantly different at different points of measurement in the intervention group (first, second, and third time-points) (P = 0.016). An increase was observed in the intervention group at the second time-point compared to the first time-point (84.2–88.4, P < 0.001) and in the third time-point compared to the first time-point, (87.9), which was also statistically significant (P < 0.001). According to the results of post hoc tests, there was a decrease in quality of life in the control group at the second time-point compared to the first time-point and the average score of mothers decreased from 82.9 to 75.3, which was statistically significant (P < 0.001). Spiritual self-care training can increase the quality of life and can be used as a form of holistic nursing care for mothers with premature infants in neonatal intensive care units.