A facilitative role for corticosterone in the acquisition of a spatial task under moderate stress

Emotionally charged experiences alter memory storage via the activation of hormonal systems. Previously, we have shown that compared with rats trained for a massed spatial learning task in the water maze in warm water (25°C), animals that were trained in cold water (19°C) performed better and showed higher levels of the stress hormone corticosterone. Here, we examined whether manipulating the levels of corticosterone can determine the strength of spatial information acquisition and retention. Rats were injected with metyrapone (25, 50, and 75 mg/kg, i.p.) or with corticosterone (10 and 25 mg/kg, i.p.) and trained in a massed spatial task in either cold (19°C) or warm (25°C) water. We found that whereas animals injected with vehicle performed well in the spatial task in cold water (moderate stress), rats injected with the intermediate metyrapone dose showed impairment in performance. Moreover, whereas animals injected with vehicle on average did not perform well in warm water (mild stress), rats injected with the lower corticosterone dose showed improvement in performance in warm water. These two mirror experiments of corticosterone blockade and enhancement strongly suggest that corticosterone is instrumental in the acquisition and retention of the spatial learning task.     

Looking on the One We Have Pierced: Repentance,Resurrection, and Winnicott's “Capacity for Concern”

This work presents a view of Christian repentance as a process analogous to the development of Winnicott's capacity for concern and illuminated by Rowan Williams' theology of the Resurrection. One begins with fear of forfeiting one's attachment to the divine good mother, confronts the evidence of one's destructiveness in the Passion of Christ, experiences the risen Christ's object survival and acceptance of reparations, and attains a desire to contribute-in to God and neighbor.     

More about brows: how poses that change brow position affect perceptions of gender

The speeded categorisation of gender from photographs of men's and women's faces under conditions of vertical brow and vertical head movement was explored in two sets of experiments. These studies were guided by the suggestion that a simple cue to gender in faces, the vertical distance between the eyelid and brow, could support such decisions. In men this distance is smaller than in women, and can be further reduced by lowering the brows and also by lowering the head and raising the eyes to camera. How does the gender-classification mechanism take changes in pose into account? Male faces with lowered brows (experiment 1) were more quickly and accurately categorised (there was little corresponding 'feminisation' of raised-brow faces). Lowering gaze had a similar effect, but failed to interact with head lowering in a simple manner (experiment 2). We conclude that the initial classification of gender from the facial image may not involve normalisation of the face image to a canonical state (the 'mug-shot view') for expressive pose (brow movement and direction of gaze). For head pose (relative position of the features when the face is not viewed head-on), normalisation cannot be ruled out. Some perceptual mechanisms for these effects, and their functional implications, are discussed.     

Attention and social functioning in children with malformations of cortical development and stroke

Attention and social functioning and their interrelationships have not been routinely examined in children with early brain insult (EBI). This study aimed to describe attention and social functioning in children with two types of EBI: malformations of cortical development (MCD) and stroke. Children diagnosed with MCD (n = 14, 6 males) or stroke (n = 14, 8 males) aged 8 to 14 years (M = 12 years 11 months) completed neuropsychological assessments to examine attention processes. Primary caregivers completed a questionnaire to assess executive components of children's attention and teachers completed a questionnaire to measure children's social functioning. Brain scans (MRI or CT) were coded by a pediatric neuroradiologist. Higher rates of impairments in attention and social function were found in children with EBI compared with normative expectations. Children with MCD experienced more global and clinically significant levels of impairment than children with stroke; though impairments were present in both groups. A strong association between executive components of attention and social function was observed. In addition, complex attention processes were associated with social function. The findings emphasize the reciprocity between attention, behavior and social outcomes, and the vulnerability of social function following EBI.     

TRAINING STAFF TO INCREASE MANDING IN STUDENTS WITH AUTISM: TWO PRELIMINARY CASE STUDIES

Two case studies evaluated two versions of behavioral skills training on peer‐to‐peer manding. Case Study 1 evaluated the full package of instructions, modeling, rehearsal, and feedback, and Case Study 2 used modeling and feedback only. Both case studies employed AB designs. In both case studies, staff increased correct teaching responses, and students increased the number of independent peer‐to peer mands. These pilot data suggest that staff can readily acquire teaching skills to increase peer‐to‐peer manding and that modeling and feedback may be sufficient to train staff to do so. Copyright © 2012 John Wiley & Sons, Ltd.     

Adult mice maintained on a high-fat diet exhibit object location memory deficits and reduced hippocampal SIRT1 gene expression

Mounting evidence has established that diet-induced obesity (DIO) is associated with deficits in hippocampus-dependent memory. The bulk of research studies dealing with this topic have utilized rats fed a high-fat diet as an experimental model. To date, there has been a paucity of research studies that have established whether the memory deficits exhibited in DIO rats can be recapitulated in mice. Moreover, the majority of experiments that have evaluated memory performance in rodent models of DIO have utilized memory tests that are essentially aversive in nature (i.e., Morris water maze). The current study sought to fill an empirical void by determining if mice maintained on a high-fat diet exhibit deficits in two non-aversive memory paradigms: novel object recognition (NOR) and object location memory (OLM). Here we report that mice fed a high-fat diet over 23 weeks exhibit intact NOR, albeit a marked impairment in hippocampus-dependent OLM. We also determined the existence of corresponding aberrations in gene expression within the hippocampus of DIO mice. DIO mice exhibited significant reductions in both SIRT1 and PP1 mRNA within the hippocampus. Our data suggest that mice maintained on a high-fat diet present with impaired hippocampus-dependent spatial memory and a corresponding alteration in the expression of genes that have been implicated in memory consolidation.     

Why they leave: the impact of stereotype threat on the attrition of women and minorities from science, math and engineering majors

This paper examines the effects of group performance anxiety on the attrition of women and minorities from science, math, and engineering majors. While past research has relied primarily on the academic deficits and lower socioeconomic status of women and minorities to explain their absence from these fields, we focus on the impact of stereotype threat—the anxiety caused by the expectation of being judged based on a negative group stereotype. Using data from the National Longitudinal Survey of Freshmen, our findings indicate that minorities experience stereotype threat more strongly than whites, although women do not suffer from stereotype threat more than men. Our findings also reveal that stereotype threat has a significant positive effect on the likelihood of women, minorities, and surprisingly, white men leaving science, technology, engineering and math majors.     

Temperament and Happiness in Children in India

The relation between temperament and happiness was assessed in a sample of 441 children aged 7–14 years drawn from a population in Northern India. Parents assessed their children’s happiness and rated their children’s temperament using the Emotionality, Activity, and Sociability Temperament Survey (EAS). Children self-reported their own happiness using a single-item measure, the Oxford Happiness Scale Short Form, and the Subjective Happiness Scale. Parents’ temperament ratings conformed to the four factor structure proposed by Buss and Plomin (Temperament: early developing personality traits. Lawrence Erlbaum Associates, Hillsdale, 1984): Emotionality, Activity, Sociability, and Shyness. Temperament accounted for between 4 and 11% of the variance in children’s happiness depending on the measures. Children who were more social and active, and less shy, were happier. This result parallels the well-established relation between happiness and personality in adults and is similar to recent research on happiness and temperament in children; temperament traits akin to extraversion were positively associated with happiness. However, despite that neuroticism and its temperament counterpart are strongly and consistently linked to happiness in adults, the relation between happiness and the temperament trait associated with neuroticism (i.e., Emotionality) was weak. This suggests that the relations between temperament and happiness in children may not completely generalize across cultures.     

Would introverts be better off if they acted more like extraverts? Exploring emotional and cognitive consequences of counterdispositional behavior

People enjoy acting extraverted, and this seems to apply equally across the dispositional introversion-extraversion dimension (Fleeson, Malanos, & Achille, 2002). It follows that dispositional introverts might improve their happiness by acting more extraverted, yet little research has examined potential costs of this strategy. In two studies, we assessed dispositions, randomly assigned participants to act introverted or extraverted, and examined costs-both emotional (concurrent negative affect) and cognitive (Stroop performance). Results replicated and extended past findings suggesting that acting extraverted produces hedonic benefits regardless of disposition. Positive affect increased and negative affect did not, even for participants acting out of character. In contrast, we found evidence that acting counterdispositionally could produce poor Stroop performance, but this effect was limited to dispositional extraverts who were assigned to act introverted. We suggest that the positive affect produced by introverts' extraverted behavior may buffer the potentially depleting effects of counterdispositional behavior, and we consider alternative explanations. We conclude that dispositional introverts may indeed benefit from acting extraverted more often and caution that dispositional extraverts may want to adopt introverted behavior strategically, as it could induce cognitive costs or self-regulatory depletion more generally.