Glucocorticoid administration into the dorsal striatum [corrected] facilitates memory consolidation of inhibitory avoidance training but not of the context or footshock components

It is well established that glucocorticoid administration into a variety of brain regions facilitates memory consolidation of fear-conditioning tasks, including inhibitory avoidance. The present findings indicate that the natural glucocorticoid corticosterone administered into the dorsal striatum (i.e., caudate nucleus) of male Wistar rats produced dose- and time-dependent enhancement of inhibitory avoidance memory consolidation. However, as assessed with a modified inhibitory avoidance procedure that took place on two sequential days to separate context training from footshock training, corticosterone administration into the dorsal striatum did not enhance memory of either the contextual or aversively motivational aspects of the task.     

Boolos and the Metamathematics of Quine's Definitions of Logical Truth and Consequence

The paper is concerned with Quine's substitutional account of logical truth. The critique of Quine's definition tends to focus on miscellaneous odds and ends, such as problems with identity. However, in an appendix to his influential article On Second Order Logic, George Boolos offered an ingenious argument that seems to diminish Quine's account of logical truth on a deeper level. In the article he shows that Quine's substitutional account of logical truth cannot be generalized properly to the general concept of logical consequence. The purpose of this paper is threefold: first, to introduce the reader to the metamathematics of Quine's substitutional definition of logical truth; second, to make Boolos' result accessible to a broader audience by giving a detailed and self-contained presentation of his proof; and, finally, to discuss some of the possible implications and how a defender of the Quinean concepts might react to the challenge posed by Boolos' result.     

Predictive Factors of Spiritual Quality of Life during the COVID-19 Pandemic: A Multivariate Analysis

Journal of Religion and Health - COVID-19 has led to the implementation of various social and sanitary measures, impacting populations’ quality of life. Aims: Documenting the spiritual...     

Adult outcomes as a function of an early childhood educational program: an Abecedarian Project follow-up

Adult (age 30) educational, economic, and social-emotional adjustment outcomes were investigated for participants in the Abecedarian Project, a randomized controlled trial of early childhood education for children from low-income families. Of the original 111 infants enrolled (98% African American), 101 took part in the age 30 follow-up. Primary indicators of educational level, economic status, and social adjustment were examined as a function of early childhood treatment. Treated individuals attained significantly more years of education, but income-to-needs ratios and criminal involvement did not vary significantly as a function of early treatment. A number of other indicators were described for each domain. Overall, the findings provide strong evidence for educational benefits, mixed evidence for economic benefits, and little evidence for treatment-related social adjustment outcomes. Implications for public policy are discussed.     

Zuckerman-Kuhlman-Aluja Personality Questionnaire (ZKA-PQ) and Cloninger's Temperament and Character Inventory Revised (TCI-R): a comparative study

The aim of this study was to compare the psychometric properties (normal distribution values, reliabilities and factor structure) of the Zuckerman-Kuhlman-Aluja Personality Questionnaire (ZKA-PQ) and the Temperament and Character Inventory revised (TCI-R). The total sample consisted of 482 subjects (53.1% men and 46.9% women) from diverse age. Results showed somewhat better psychometric properties, like reliability and facet-factor structure, for the ZKA-PQ than the TCI-R. The expected five-factor facet structure of the ZKA-PQ was clear found. However, the seven-factor structure of TCI-R was not clear and it did not show a clear distinction between Temperament and Character factors. When ZKA-PQ and TCI-R variables are analyzed together, the ZKA-PQ factors are related to the Character as well as the Temperament factors. In some cases they represent the opposite poles of ZKA-PQ factors; for example, Neuroticism versus Self-Directiveness and Aggression versus Cooperativeness. Some are directly and highly related to ZKA-PQ factors; for example, Sensation Seeking and Novelty Seeking, Extraversion and Reward Dependence, Neuroticism and Harm Avoidance, and Activity and Persistence.     

Slim Futures and the Fat Pill: Civic Imaginations of Innovation and Governance in an Engagement Setting

Innovation politics is seen as an ever more central area of public policy, and as a key means for shaping societal futures. Particularly in Europe, with its history of controversial public debates about innovations, the idea that scientific progress is automatically equated with societal progress seems hard to sustain. Broader public participation within techno-scientific governance seems necessary; though who is to participate in which form often remains unclear. Increasingly, when the innovation process is discussed in both policy and academia, the question of when public engagement should take place in the innovation process is addressed using common models such as ‘upstream engagement’. However, these discussions about public engagement often assume a top-down approach, and pay little attention to citizens' perspectives. To address this gap in the literature, this article will ask the following questions: what tacit understandings of techno-scientific innovation and governance do citizens have; and how do they relate their understandings of the form, structure and dynamics of these innovation processes to their visions of governance and participation? How do specific cultural forms of conceptualising innovation open up or close down particular possibilities of governance and public participation, hence privileging the involvement of certain actors and not others? To address these questions, we analyse the discussions in a long-term public engagement setting involving both genome scientists and citizens in Austria.     

Remarks on Independence Proofs and Indirect Reference

In the last two decades, there has been increasing interest in a re-evaluation of Frege's stance towards consistency- and independence proofs. Papers by several authors deal with Frege's views on these topics. In this note, I want to discuss one particular problem, which seems to be a main reason for Frege's reluctant attitude towards his own proposed method of proving the independence of axioms, namely his view that thoughts, that is, intensional entities are the objects of metatheoretical investigations. This stands in contrast to more straightforward interpretations, which claim that Frege's hesitancy is mainly due to worries concerning the logical constants or what counts as a logical inference.     

Why the Concept of Moral Status Should be Abandoned

The use of the concept of moral status is commonplace today in debates about the moral consideration of entities lacking certain special capacities, such as nonhuman animals. This concept has been typically used to defend the view that adult human beings have a status higher than all those entities. However, even those who disagree with this claim have often accepted the idea of moral status as if it were part of an undisputed received way of thinking in ethics. This paper argues that the use of this concept, however common, distorts our understanding of how to behave towards different individuals in different circumstances. When moral status is identified with the interest in living or the capacity for well-being, it becomes an arbitrary and irrelevant criterion. When it is used as a synonym of moral consideration or considerability, in a way that is compatible with the principle of equal consideration, it becomes trivial and confusing. When used, instead, to defend the unequal moral consideration of interests of equal weight, it has several implausible implications. In particular, the claim that unequal status is justified because of the value (either final or intrinsic, or instrumental) of cognitive capacities implausibly entails that our exercising those capacities should have priority over the promotion of our wellbeing. The idea of full moral status is also problematic as it implies the possibility of status monsters. In addition, its use is based in a misconceived way of what it would really entail to have a full status by virtue of having rational capacities. The paper concludes that we have strong reasons to abandon the concept of moral status altogether.     

Perceptual control models of pursuit manual tracking demonstrate individual specificity and parameter consistency

Attention, Perception, & Psychophysics - Computational models that simulate individuals’ movements in pursuit-tracking tasks have been used to elucidate mechanisms of human motor control....