Prevalence of ADHD and comorbid disorders among elementary school children screened for disruptive behavior

In the context of a school-based prevention of conduct disorder program, 7,231 first- through fourth-grade children were screened for cross-setting disruptive behavior. Frequencies of DSM-III-R psychiatric disorders and patterns of comorbidity were assessed. We also examined the association of psychiatric diagnosis with child and parent characteristics to determine differential risk based on diagnostic subgroups. Attention deficit hyperactivity disorder (ADHD) and oppositional-defiant disorder (ODD) were the most frequent diagnoses. Mood and anxiety disorders were infrequent as single diagnoses. Patterns of comorbidity demonstrated that both externalizing and internalizing disorders commonly cooccurred with ADHD. More severe degrees of psychopathology and psychosocial risk accrued to the subgroup of youths with ADHD plus a comorbid externalizing disorder.This study was supported by grant MN-46584 from the National Institute of Mental Health.     

Active and passive avoidance following the administration of systemic DSP4, xylamine, or p-chloroamphetamine

Groups of rats were administered either DSP4 (50 mg/kg, ip), xylamine (50 mg/kg, ip), or p-chloroamphetamine (2 X 10 mg/kg, ip), either 2 weeks or 1 week before the testing of two-way active avoidance. DSP4 and xylamine, the selective noradrenaline (NA) neurotoxins, caused a two-way avoidance impairment but p-chloroamphetamine, the selective 5-hydroxytryptamine (5-HT) neurotoxin, did not do so. Pretreatment with desipramine (20 mg/kg, ip) blocked the avoidance impairment caused by DSP4 and xylamine treatment. Neither DSP4 nor xylamine caused any alteration of passive avoidance retention. The biochemical analyses indicated severe NA, but not 5-HT, depletions in the DSP4 and xylamine conditions and drastic 5-HT, but not NA, depletions in the p-chloroamphetamine conditions. These results confirm and extend earlier findings concerning the role of NA in avoidance behavior.     

Iconic memory and visible persistence

There are three senses in which a visual stimulus may be said to persist psychologically for some time after its physical offset. First, neural activity in the visual system evoked by the stimulus may continue after stimulus offset (“neural persistence”). Second, the stimulus may continue to be visible for some time after its offset (“visible persistence”). Finally, information about visual properties of the stimulus may continue to be available to an observer for some time after stimulus offset (“informational persistence”). These three forms of visual persistence are widely assumed to reflect a single underlying process: a decaying visual trace that (1) consists of afteractivity in the visual system, (2) is visible, and (3) is the source of visual information in experiments on decaying visual memory. It is argued here that this assumption is incorrect. Studies of visible persistence are reviewed; seven different techniques that have been used for investigating visible persistence are identified, and it is pointed out that numerous studies using a variety of techniques have demonstrated two fundamental properties of visible persistence: theinverse duration effect (the longer a stimulus lasts, the shorter is its persistence after stimulus offset) and theinverse intensity effect (the more intense the stimulus, the briefer its persistence). Only when stimuli are so intense as to produce afterimages do these two effects fail to occur. Work on neural persistences is briefly reviewed; such persistences exist at the photoreceptor level and at various stages in the visual pathways. It is proposed that visible persistence depends upon both of these types of neural persistence; furthermore, there must be an additional neural locus, since a purely stereoscopic (and hence cortical) form of visible persistence exists. It is argued that informational persistence is defined by the use of the partial report methods introduced by Averbach and Coriell (1961) and Sperling (1960), and the term “iconic memory” is used to describe this form of persistence. Several studies of the effects of stimulus duration and stimulus intensity upon the duration of iconic memory have been carried out. Their results demonstrate that the duration of iconic memory is not inversely related to stimulus duration or stimulus intensity. It follows that informational persistence or iconic memory cannot be identified with visible persistence, since they have fundamentally different properties. One implication of this claim that one cannot investigate iconic memory by tasks that require the subject to make phenomenological judgments about the duration of a visual display. In other words, the so-called “direct methods” for studying iconic memory do not provide information about iconic memory. Another implication is that iconic memory is not intimately tied to processes going on in the visual system (as visible persistence is); provided a stimulus is adequately legible, its physical parameters have little influence upon its iconic memory. The paper concludes by pointing out that there exists an alternative to the usual view of iconic memory as a precategorical sensory buffer. According to this alternative, iconic memory is post-categorical, occurring subsequent to stimulus identification. Here, stimulus identification is considered to be a rapid automatic process which does not require buffer storage, but which provides no information about episodic properties of a visual stimulus. Information about these physical stimulus properties must, in some way, be temporarily attached to a representation of the stimulus in semantic memory; and it is this temporarily attached physical information which constitutes iconic memory.     

Children’s use of phonological encoding when reading for meaning

The role of phonological recoding in children’s reading was investigated by means of a task requiring comprehension of sentence meaning: The child’s task was to decide whether a sequence of printed letter strings was a meaningful sentence or not. Meaningless sentences that are meaningful when phonologically recoded (e.g., “He ran threw the street”) produced more incorrect responses than did meaningless sentences that remain meaningless when phonologically recoded (e.g., “He ran sew the street”). The difference in error rates between the two sentence types diminished as a function of age. Control experiments showed that these results were not due to visual similarity effects, nor to imperfect ability to spell homophones. It was concluded that very young readers rely extensively on phonological recoding when reading for meaning; as they grow older, reliance on visual encoding becomes progressively more important.     

Saccade latency and warning signals: Effects of auditory and visual stimulus onset and offset

Previous studies have found that a nonspecific visual event occurring at the fovea 50–150 msec after the onset of a peripheral target delayed the initiation of the saccade to that target. The present studies replicated and extended this finding by studying the effects of both visual and auditory warning signals, by examining the effects of onset and offset warning on manual response latency, and by investigating the effects of presenting the warning events in the periphery of the visual field. The results indicated that the interfering effects occur with visual but not auditory stimuli, with saccades but not motor responses, and when the visual warning event occurs either foveally or in the subject’s periphery. Implications for the processes involved are discussed.     

The more,the better?: Number of decisions as a determinant of memorability

Three experiments tested alternative explanations to the Johnson-Laird, Gibbs, and deMowbray (1978) proposal that the number of decisions made about a word is a major determinant of its memorability. The alternatives considered were increased processing time, retrieval aids, and the number of positive decisions. In Experiment 1, subjects made a speeded classification about each word for a category defined by three properties. Though items with more target properties were processed longer and better remembered, within a property level processing time was not associated with better memory. In Experiment 2, subjects received three properties, but different groups responded “Yes” to words with all three properties, words with any of the three properties, or whether words had each of the properties. As predicted by the number-of-decisions hypothesis, but not by the other hypotheses, with an increasing number of target properties, recall generally increased in the ALL group, decreased in the ANY group, and remained constant in the EACH group. In Experiment 3, this recall pattern was replicated with a different set of two target properties. The number-of-decisions notion is contrasted to the elaboration principle, and a simple model is proposed. It is concluded that the number of decisions is a useful technique for investigating within-level encoding differences     

Phonological processing during silent reading in aphasic patients

In a task involving the detection of a predesignated letter during the silent reading of a series of passages, left-brain-damaged aphasic patients and right-brain-damaged patients showed patterns of performance consistent with those of normal individuals. Both of the brain-damaged groups were more likely to detect letters when they were pronounced in a typical way (e.g., g in "ago") than in an atypical way (e.g., g in "through"), suggesting the use of phonological recoding during silent reading. In addition, both of these groups were more likely to detect letters when they occurred in content than in function words, suggesting a differential processing of these word types. Possible differences in the strategies predominantly relied on for phonological recoding and for the differential processing of content and function words by different groups of patients are discussed.