Fetal Alcohol Spectrum Disorders: Neuropsychological and Behavioral Features

Heavy prenatal alcohol exposure can cause alterations to the developing brain. The resulting neurobehavioral deficits seen following this exposure are wide-ranging and potentially devastating and, therefore, are of significant concern to individuals, families, communities, and society. These effects occur on a continuum, and qualitatively similar neuropsychological and behavioral features are seen across the spectrum of effect. The term fetal alcohol spectrum disorders (FASD) has been used to emphasize the continuous nature of the outcomes of prenatal alcohol exposure, with fetal alcohol syndrome (FAS) representing one point on the spectrum. This paper will provide a comprehensive review of the neuropsychological and behavioral effects of heavy prenatal alcohol exposure, including a discussion of the emerging neurobehavioral profile. Supporting studies of lower levels of exposure, brain-behavior associations, and animal model systems will be included when appropriate.     

Associations Between Adolescents’ Family Stressors and Life Satisfaction

Extant literature suggests that family stressors co-occur with elevated adolescent psychopathology. Few studies have examined the relationship between family stressors and life satisfaction, a positive indicator of mental health. The current study explored the relationships between specific family stressors (i.e., low socioeconomic status, disrupted family structure, cumulative major life events, and perceived interparental conflict) and adolescents’ life satisfaction in a sample of 181 middle school students. Participants completed psychometrically sound self-report measures of the aforementioned constructs. Results from a simultaneous regression analysis indicated that the four forms of family stress accounted for 37 % of the variance in life satisfaction; experiencing major life events (β = ?0.31, p < .05) and perceiving interparental conflict (β = ?0.41, p < .05) emerged as unique predictors of life satisfaction. Implications and directions for future research are discussed.     

Building Schools’ Readiness to Implement a Comprehensive Approach to School Safety

Research consistently finds that a comprehensive approach to school safety, which integrates the best scientific evidence and solid implementation strategies, offers the greatest potential for preventing youth violence and promoting mental and behavioral health. However, schools and communities encounter enormous challenges in articulating, synthesizing, and implementing all the complex aspects of a comprehensive approach to school safety. This paper aims to bridge the gap between scientific evidence and the application of that evidence in schools and communities by defining the key components of a comprehensive approach to school safety and describing how schools can assess their readiness to implement a comprehensive approach. We use readiness and implementation data from the Safe Communities Safe Schools project to illustrate these challenges and solutions. Our findings suggest that (1) readiness assessment can be combined with feasibility meetings to inform school selection for implementation of a comprehensive approach to school safety and (2) intentionally addressing readiness barriers as part of a comprehensive approach may lead to improvements in readiness (motivation and capacity) to effectively implement a comprehensive approach to school safety.     

Refining the experimental analysis of academic skills deficits: part II. Use of brief experimental analysis to evaluate reading fluency treatments

The technology of brief experimental analysis is just beginning to be used for identification of effective treatments for individual students who experience difficulty with oral reading fluency. In this study, the effect of a reading fluency treatment package was examined on easy and hard passages, and generalization was assessed on passages with high content overlap. The results suggest that the treatment package increased reading fluency for all 3 students. Effects were moderated by difficulty level for all 3 students. Results are discussed in terms of future refinements to the procedures, validation of the methods, and potential applications in clinical and school settings.     

Accelerated cognitive aging in diabetic rats is prevented by lowering corticosterone levels

Diabetes and normal aging are both characterized by increases in levels of glucocorticoids. Because long-term exposure to elevated glucocorticoids can be detrimental to hippocampal function, we evaluated the performance of young diabetic rats in the 14-unit T-maze, a task that is sensitive to hippocampal deficits. To assess the contribution of diabetes-induced elevations in corticosterone levels, we examined maze learning in diabetic rats that had levels of corticosterone 'clamped' through adrenalectomy and low-dose corticosterone replacement. For comparison, we also tested a separate group of young and aged rats in the maze. Adrenally intact diabetic rats learned poorly in the 14-unit T-maze. Preventing the increases in corticosterone levels that accompanies the onset of experimental diabetes also prevented deficits in complex maze learning. The pattern of errors made by adrenally intact diabetic rats was similar to the pattern of errors made by aged rats, suggesting that the cognitive profiles of diabetic and aged rats share common features.     

Social Information Processing Skills in Children with Histories of Heavy Prenatal Alcohol Exposure

Based on caregiver report, children with prenatal alcohol exposure have difficulty with social functioning, but little is known about their social cognition. The current study assessed the social information processing patterns of school-age children with heavy prenatal alcohol exposure using a paradigm based on Crick and Dodge’s reformulated six-stage model. Fifty-two children (aged 7–11) with and without heavy prenatal alcohol exposure were tested using a structured interview measure of social information processing involving 18 videotaped vignettes of children in group entry and provocation situations. Alcohol-exposed children displayed maladaptive processing patterns on the goal, response generation, and response evaluation steps in group entry situations, and encoding, attribution, response evaluation, and enactment steps during provocation situations. Children with heavy prenatal alcohol exposure also had difficulty on the Test of Problem Solving, and performance correlated with social information processing measures. Such difficulties may lead to problems in social functioning and warrant early intervention.     

Age-related differences on a new test of temporal order memory for everyday events

We developed a new test to examine incidental temporal order memory for a self-generated sequence of tasks one might complete in everyday life. Young and older adults were given 10 cards, each listing a task one might accomplish in a typical day. Participants were asked to self-generate a “to do” list by placing the 10 cards in a sequence representing the order in which they would accomplish the tasks, but were not informed of a subsequent memory test. We assessed immediate free recall, delayed free recall, and delayed cued recall for the order of the tasks in the sequence. Older adults were significantly impaired relative to young adults on immediate free recall, delayed free recall, and delayed cued recall. Correlation analyses with standardized neuropsychological tests provide preliminary evidence for construct validity for our test, which is portable and can be rapidly administered in clinical or laboratory settings.     

Psysquash: a program for the analysis of PsyScope data files

Many experiment-running programs generate output files that require selection, reduction, and formatting of the raw data before the numbers are suitable for input into statistical packages. PsySquash is a Macintosh program for the selection, organization, and summary of the tabular data that are produced by a widely used freeware data acquisition system, PsyScope. PsySquash serves as a bridge between PsyScope’s output data format and the input formats required by common statistical packages such as SAS, SPSS, and SuperAnova. An extension of PsySquash is proposed for use with arbitrary tabular data.     

ATTITUDES INFLUENCING EMPLOYMENT OF THE HANDICAPPED

This study investigates the effect of existing attitudes on employment practices of two groups of Texas employers, the first employing visually handicapped persons, and the second employing physically handicapped persons. After personal interviews, all 24 participants were administered the Survey of Interpersonal Values (SIV) and the Action, Cognition, and Emotion Test (ACET). Among conclusions drawn from the findings were that employers of the visually handicapped indicate their willingness to hire persons with physical disabilities, that employers who show willingness to employ handicapped personnel at the professional level tend to value leadership traits in employees, that employers may not carry through with actual employment of the handicapped even though they communicate interest in and tolerance for these individuals, that employers' positive attitudes appear to relate significantly to positive experiences with handicapped workers, and that the larger the population center the more receptive the attitudes of employers toward the handicapped.