Effects of Lipopolysaccharide on Consolidation of Partial Learning in the Y-Maze

Research on consolidation of long-term memory suggests that acute immune system activation induced by endotoxin lipopolysaccharide (LPS) may disrupt consolidation of newly acquired learning. Adult male Sprague-Dawley rats were trained to perform a simple Y-maze task and were immediately afterwards administered LPS (15 microg/kg) or saline. After a seven-day interval, subjects were returned to the Y-maze and were retrained to criterion. It was found that subjects treated with saline required significantly fewer trials to relearn the task relative to the LPS group and a no-partial-learning control group, which themselves did not differ. These results are most readily explained in terms of a disruptive effect of acute immune system activation on consolidation of newly induced acquired memories.     

When the sexes need not differ: Emotional responses to the sexual and emotional aspects of infidelity

This study assessed whether previously reported sex differences in jealousy could be accounted for by other related emotions. Participants were presented with hypothetical scenarios involving both a sexual and an emotional infidelity, then were asked how jealous, angry, hurt, and disgusted they would be (using continuous scales). The results replicate the sex difference in response to sexual and emotional infidelity, demonstrate that it is robust when continuous measures are used, and confirm that it is unique to jealousy. Sex differences did not emerge for anger, hurt, or disgust. Instead, sexual infidelity elicited greater anger and disgust, and less hurt, than emotional infidelity, for both women and men. The results also suggest that it is the jealous response to an emotional infidelity that best discriminates women from men, and that both women and those participants in a serious, committed relationship reported significantly greater intensity in their emotional reactions, as compared to men and those not in a committed relationship.     

How Work-Family Research Can Finally Have an Impact in Organizations

Although work-family research has mushroomed over the past several decades, an implementation gap persists in putting work-family research into practice. Because of this, work-family researchers have not made a significant impact in improving the lives of employees relative to the amount of research that has been conducted. The goal of this article is to clarify areas where implementation gaps between work-family research and practice are prevalent, discuss the importance of reducing these gaps, and make the case that both better and different research should be conducted. We recommend several alternative but complementary actions for the work-family researcher: (a) work with organizations to study their policy and practice implementation efforts, (b) focus on the impact of rapid technological advances that are blurring work-family boundaries, (c) conduct research to empower the individual to self-manage the work-family interface, and (d) engage in advocacy and collaborative policy research to change institutional contexts and break down silos. Increased partnerships between industrial-organizational (I-O) psychology practitioners and researchers from many industries and disciplines could break down silos that we see as limiting development of the field.     

A new measure for dispositional optimism and pessimism in young children

We describe here a new test for dispositional optimism and pessimism in young children, the Parent‐rated Life Orientation Test of children (the PLOT) and assess its psychometric properties. Two hundred and twenty one mother–father pairs rated their children's (mean age = 8.1, SD = 0.3 years) dispositional optimism and pessimism using a new scale, the PLOT, including four optimism and four pessimism items. We associated the PLOT with parent‐rated self‐esteem (Behavioral Rating Scale of Presented Self‐Esteem in Young Children), social competence (Social Competence and Behaviour Evaluation Scale, the SCBE‐30), psychiatric symptoms (Child Behaviour Checklist, the CBCL) and temperament (Children's Behaviour Questionnaire, the CBQ) of the child. A confirmatory factor analysis (CFA) of the mother‐ and father‐rated PLOT revealed a significantly better fit for a two‐ over a one‐factor solution (p < 0.001). The optimism and pessimism subscales displayed good reliabilities, inter‐parental agreement and modest to moderate associations, in the expected direction, with the measures of self‐esteem, social competence, temperament and behaviour problems. To conclude, the PLOT shows good construct and convergent validity and reliability. The findings encourage its use to assess early emerging generalized expectancies of positive and negative outcomes in young children. Copyright © 2009 John Wiley & Sons, Ltd.     

Investigating the relationship between meaningful time use and health in 18‐ to 25‐year‐old unemployed people in New South Wales,Australia

A vast body of literature has reported on the association between unemployment and poor psychological health. Nonetheless, there remains limited understanding of the influence of meaningfulness of time use, suggested by some to be the key mediator between time use and health. This project set out to explore the association between meaningful time use and health in 18‐ to 25‐year‐old unemployed people. In April 2007, 150 unemployed 18‐ to 25‐year‐old Australians (56% female) completed an online survey package exploring meaningfulness of time use and health. Hierarchical stepwise regression equations were developed to analyse the relationship between psychological health and measures of meaningful time use. Results provided partial support for the hypothesis that measures of meaningful time use would contribute to the prediction of psychological health. The addition of the person measure for the combined construct of ‘meaningful time use’ failed to make a significant contribution towards the prediction of psychological health. However, ‘reason for doing the activity’ emerged as a significant predictor. Findings provide preliminary evidence for the establishment of activity‐based programs to support young unemployed people. Further research is required to evaluate the outcomes of such programs and to replicate this study with other groups of unemployed individuals. Copyright © 2010 John Wiley & Sons, Ltd.     

Effects of warned and unwarned demand transitions on vigilance performance and stress

The present study was designed to explore the effects of warned and unwarned demand transitions in vigilance on performance and self-reported stress. Twenty observers (10 women and 10 men) were assigned at random to each of six conditions resulting from the factorial combination of signal salience (high and low salience signals) and switching (no switch, switch with warning, and switch without warning). Performance metrics and self-reported stress state (Task Engagement, Distress, and Worry) were collected. While demand transitions did destabilize subsequent performance, increasing intra-individual variability, overall performance efficiency was uninfluenced by either switching or warning. Demand transitions, whether warned or not, increased self-reported distress. A dynamic model of performance stress may be necessary and research employing vigilance tasks in the future may be useful for developing this performance-stress model.     

The Rationale Behind Revision-Rule Semantics

According to Gupta and Belnap, the “extensional behavior” of ‘true’ matches that of a circularly defined predicate. Besides promising to explain semantic paradoxicality, their general theory of circular predicates significantly liberalizes the framework of truth-conditional semantics. The authors’ discussions of the rationale behind that liberalization invoke two distinct senses in which a circular predicate’s semantic behavior is explained by a “revision rule” carrying hypothetical information about its extension. Neither attempted explanation succeeds. Their theory may however be modified to employ a relativized notion of extension. The resulting contextualist semantics for ‘true’ construes circularity as a pragmatic phenomenon.     

Blood lead (Pb) levels: a potential environmental mechanism explaining the relation between socioeconomic status and cardiovascular reactivity in children.

OBJECTIVE: A number of studies have shown an association between socioeconomic status (SES) and cardiovascular reactivity to acute stress. In addition, the authors recently reported that higher early childhood blood lead (Pb) levels are associated with significantly greater total peripheral (vascular) resistance (TPR) responses to acute stress. It is not known whether the SES-TPR association is mediated by underlying differences in blood lead levels. DESIGN: Participants were 9.5-year-old children (N=122) with established early childhood blood lead levels. MAIN OUTCOME MEASURES: Family SES was measured using the Hollingshead Index, blood lead levels were abstracted from pediatrician and state records, and children's cardiovascular responses to acute stressors were measured in the laboratory with impedance cardiography and an automated blood pressure monitor. RESULTS: Lower family SES was shown to be associated with significantly higher blood lead levels as well as significantly heightened systolic blood pressure, diastolic blood pressure, and TPR responses to acute stress tasks. A mediational analysis confirmed that Pb was a significant mediator of the SES-TPR reactivity association; some evidence also suggested moderation. CONCLUSION: These results suggest the importance of considering the chemical environment as well as social and psychological environment when evaluating cardiovascular effects of low SES.     

mTOR signaling in the hippocampus is necessary for memory formation

It is widely accepted that the formation of long-term memory (LTM) requires mRNA translation, but little is known about the cellular mechanisms in the brain that regulate this process. Mammalian target of rapamycin (mTOR) is a key regulator of translational efficacy and capacity. Here, we show that LTM formation of one-trial inhibitory avoidance (IA) in rats, a hippocampus-dependent fear-motivated learning task, requires mTOR activation. IA training is specifically associated with a rapid increase in the phosphorylation state of mTOR and its substrate ribosomal S6 kinase (p70S6K). Bilateral intra-CA1 infusion of rapamycin, a selective mTOR inhibitor, 15 min before, but not immediately after training completely hinders IA LTM without affecting short-term memory (STM) retention. Therefore, our findings indicate that the regulation of hippocampal mRNA translation is a major control step in memory consolidation.