Hippocampal deafferentation: transplantderived reinnervation and functional recovery

A brief review is provided of the capacity of neural tissue transplants to reinnervate the deafferented hippocampus and repair functional deficits induced by the lesion. The techniques for transplantation of solid pieces of embryonic septum, locus coeruleus or raphe nuclei, or tissue suspensions of embryonic septum, to the adult rat hippocampus are described. Such grafts manifest good long-term survival, provide a good reinnervation of the hippocampus that is histochemically and biochemically appropriate and specific, can establish ultrastructural synaptic contacts with the host, and are electrophysiologically active. Rats with septal grafts manifest recovery of the capacity to learn certain aspects of radial 8-arm maze, T-maze alternation and Morris water-maze tasks. Rats with locus coeruleus grafts manifest an amelioration of lesion-induced hyperactivity. It is concluded that neural tissue transplantation provides a powerful new tool in the study of the functional organization of the hippocampus and its various neurotransmitter-specific afferent systems.     

Premenstrual syndrom

Premenstrual syndrome is a condition with cyclical mood changes occurring in 30 % of the female population of fertile ages. The symptom development is very closely related to the luteal phase indicating the existence of one or more factors during the luteal phase that provoke mental symptoms in sensitive patients. This is further supported by the fact that hysterectomized women with no menstrual bleedings but with the ovarian hormone cycle continue to show cyclical mood changes without having the cycle phase. The nature of the symptom provocating factor is still unknown but the ovarian hormones progesterone and/or estradiol are suspected. This as certain women taking oral contraceptives and sequential postmenopausal estrogen-progestagen treatment achieve mood changes. Psychological and personality factors are probably also involved, at least in the degree of the mood change and the type of mood experienced.     

Constraints on strategy construction in a speeded discrimination task

In three experiments, subjects reported the identity of a word (above or below) that appeared above or below a fixation point. On some trials, a cue presented 100, 200, 400, 600, 800, or 1,000 msec before the word indicated the relation between position and identity (i.e., whether the dimensions were compatible, e.g., above/above and below/below, or conflicted, e.g., above/below and below/above). On the other trials, the cue was withheld (Experiment 2) or it bore no information about the relation between dimensions (Experiment 1 and 3). In each experiment, the cue reduced reaction time below the level of no-cue or neutral-cue controls, indicating strategic use of the relation between dimensions. Experiments 1 and 2 manipulated the number of potential cues that could occur in a block. A stronger cuing effect was found when one cue could occur (Experiment 2) than when two cues could occur (Experiment 1). Experiment 3 manipulated practice; it revealed that with practice the cuing effect reached asymptote at shorter delays. The asymptote itself did not change. Experiment 4 showed that cue-delay effects were independent of warning interval (warning interval and cue delay confounded in Experiment 1, 2, and 3). The experiments demonstrate construction and utilization of strategies; they show that construction is sensitive to constraints imposed by the subject's goals and abilities and by the structure of the task environment.     

Chronic effects of electrical stimulation of muscle on the fractionated components of audio response time

Six male volunteer subjects underwent five weeks (15 sessions) of electrical stimulation (ES) of the triceps brachii muscle (medial head), participated in a pretest, and five weekly post-treatment performance tests of an elbow extension task. Response time (RSP) was electronically fractionated into the two components of reaction time (RT): premotor reaction time (PMT) and motor reaction time (MT): and movement time (MVT) for 45 degrees of elbow extension. Acceleration characteristics of the movement were quantified via a piezoelectric accelerometer mounted on a specially-built mechanism that allowed the desired motion in a transverse plane. Statistical analysis did not indicate significant treatment effects on the criterion measures, however, a significant linear trend for MT and significant linear and quadratic trends for MVT were indicated. Neuromuscular adaptation to the passage of electric current through nerve and muscle tissue was indicated by a significant quadratic trend and significant differences between all weekly accumulative (treatment) voltages. An unexpected significant negative correlation between PMT and MT was considered cause for further study. The particular technique of ES administration, although it produced consistant changes in RSP components (Ward and Grabiner 1981) was not as effective as methods described by other investigators for increased human performance.     

Gender differences in performance attributions: Students' explanations for personal success or failure

Women are often said to exhibit an externality bias in their performance attributions. To test this hypothesis, male and female college students made effort, ability, luck, and task difficulty attributions for their performance on a recent course examination. Measures of the students' affective reactions toward their performance were also obtained. Successful students, whether male or female, made internal attributions and were pleased with their performance. Stronger internal attributions were associated with more positive affective reactions for these students. Unsuccessful female students made external attributions, were displeased with their performance, and felt better when they attributed their failure to unstable factors. Unsuccessful male students were also displeased with their performance, but tended to make more internal attributions for their failure, and felt better as a result. These findings, which suggest the influence of an internality bias among men, rather than an externality bias among women, were interpreted in terms of the male sex role.     

The effects of specifying job requirements and using explicit warnings to decrease sex discrimination in employment interviews

To determine the relative effectiveness of instructions designed to reduce sex discrimination in employment interviews, 96 students rated resumes for both a male and a female applicant. In one instructional condition subjects were told the specific requirements necessary for success on the job. In a second condition subjects were warned that it was illegal to discriminate on the applicant's sex. A third condition received both instructions, and a fourth received neither. Results revealed a series of interactions suggesting that the use of legal warning alone tended to increase the ratings of male applicants in some cases and influenced how male evaluators rated all applicants in other cases. The major implications were that legal warnings may actually bias ratings in favor of male applicants and may occasionally lead male evaluators to make lenient ratings. The specification of job requirements was suggested as a viable method of reducing discrimination.This work was supported in part by funds from the Foundation of the University of North Carolina at Charlotte and from the State of North Carolina. The author wishes to thank P. S. Siegfried, J. Thomas Puglisi, and an anonymous reviewer for their comments and revisions of an earlier draft.     

Behaviors associated with “good” and “poor” outcomes in a simulated career decision

What career decision-making procedures enable people to make decisions that yield consequences congruent with their own values? The 40 “best” (most congruent) and 40 “worst” decision makers on the Career Decision Simulation were compared in a sample of 148 community college students. No significant differences appeared in the amount of double checking, number of occupations and information sources checked, amount of information collected, decision time required, and the proportion of information sought about high values. The “best” decision makers, however, were significantly more persistent in immediately seeking more information about an occupation that seemed to match one of their most important personal work values. Following a values-guided search appears more effective than simply searching exhaustively.