Cigarette smoking, urinary acidity, and nicotine excretion under natural conditions

For 40 males who smoked 20 cigarettes a day titratable acidity of the urine was significantly correlated with nicotine/cotinine excretion at several sample intervals, as was urinary pH, but not urinary acidity and daily cigarette consumption or serum COHB.     

Relative size and spatial separation: effects on the parallel-lines illusion

The parallel-lines illusion provides a prototypical example of visual-size assimilation, where the size of a test element is phenomenally skewed towards (or "averaged with") that of a context element. Most assimilation theories predict that distortion should decrease with spatial separation between context and test lengths. However, there is some disagreement about the nature of the function relating sizes of context and test elements and magnitude of assimilation. The present study tests the limits of assimilation in the parallel-lines configurations by observing the effects of a wide range of context/test size ratios, repeated over two disparate levels of spatial separation. The results replicate and extend 1979 findings by Brigell and Uhlarik, confirming that assimilation rises to a peak at midrange size ratios, only to decrease continuously as the ratios become more extreme. The functions were nonmonotonic and similar in shape for both levels of spatial separation, with an over-all decrease in distortion for configurations with the larger separation.     

Effects of auditory masking by white noise on primary stressing during spontaneous speech

6 adult subjects (3 men, 3 women) produced highly similar spontaneous speech utterances in quiet and with 90-dB SPL white noise. The frequency of occurrence of perceptual judgments of primary stressing in an utterance was not affected by the masking noise. This finding supplements our previous report that variability for stress production of fundamental frequency (fo) during spontaneous speech was preserved under short-term auditory disruption. Also, it adds further support to the contention that fo is under open-loop regulation.     

Integration of noxious stimulation across separate somatosensory communications systems: a functional theory of pain

Functional measurement analyses and psychophysical techniques were used to assess how separate, cross-modal, aversive events are integrated in judgements of pain. Subjects made magnitude estimations of noxious stimuli produced by a 6 X 6 factorial design of electric shocks and loud tones. Group data and most of the individual results were consistent with a model of linear pain summation: The estimates of pain approximated the linear sum of the pain estimates of the individual electrocutaneous and auditory components. The relation between painful sensation and current intensity could be described by a mildly expansive power function with an exponent of about 1.1. Auditorily produced painful sensation related to sound pressure level by a mildly compressive power function with an exponent of about 0.90 as a representative figure. Results are interpreted in terms of a functional theory of pain. Noxious events are first transformed to psychological scale values via stimulus-specific psychophysical transfer functions. The outputs of these functions are then combined with other pain-related internal representations of either sensory or cognitive origin, according to simple algebraic models.     

Performance of normal and neurological mutant mice on radial arm maze and active avoidance tasks

The objectives of the present study are to assess the import of gene-imposed structural alterations on behavioral performance and obtain performance data preliminary to studies of experimental mouse chimera behavior. Reeler, staggerer, and weaver neurological mutant, and control B6C3 and ichthyosis mice were tested on radial arm maze and active avoidance tasks. Weaver mice had incapacitating seizures while performing the radial arm maze task and were, therefore, removed from further testing. Staggerer mice displayed a significant deficit on both tasks compared to control mice. Homozygous reeler mice (rl/rl) also had a significant deficit on the active avoidance task compared to +/rl control mice but not significantly poorer than ichthyosis mice. However, their performance on the radial arm maze task, while initially poor, improved so that they performed the task similar to wild-type controls. Three of the reeler mice reached criterion for solving the radial arm maze task. None of the staggerer mice reached criterion. These data are discussed in terms of the value of using neurologically mutant mice in dissecting structural-functional relationships. It is suggested that the behavior of these mutants might point toward specific components of cerebellar involvement in behavioral acts.     

An assessment of decision-making as a possible factor in the age-related loss of contrast sensitivity

The possibility that changes in decision-making may contribute to the age-related decline in contrast sensitivity has been investigated in nineteen young subjects (ages 21-38 years) and twenty-seven old subjects (ages 55-92 years). A signal detection paradigm was employed in which the detection of stationary sinusoidal grating patterns was measured at 3 and 15 cycles deg-1 for a range of contrasts which were psychophysically equivalent for each subject. A decline in contrast sensitivity with age at the spatial frequencies studied was confirmed for contrast thresholds obtained both by the ascending method and from the 50% hit rate for detection of the grating pattern. The criterion adopted for decision-making, expressed as both beta and percentage bias, did not change significantly between young and old subjects at 15 cycles deg-1. At 3 cycles deg-1, criterion beta did not change significantly at X0.8, X1.0, or X1.2 contrast threshold, but at contrast giving 50% hit rate there was a significant increase with age. The percentage bias increased significantly at contrast threshold but not at 50% hit rate. It is inferred from the results that the loss of contrast sensitivity was not accountable in terms of the adoption of a more conservative criterion by older subjects. Hence visual loss in ageing is attributed to changes within the visual pathway rather than within higher decision-making centres.     

Social and solipsistic observer training: Effects on agreement with a criterion

The need to train accurate, not necessarily agreeing, observers is discussed. Intraobserver consistency as an intermediate criterion in such training is proposed and contrasted with the more familiar criterion of interobserver agreement. Videotaped observations of social interactions between handicapped and nonhandicapped preschoolers provided the medium for examining the criterion agreement of four observers trained against each type of standard. Observers generally failed to show high levels of criterion agreement whether trained to a within- or to a between-observer agreement standard. The results varied somewhat with the frequency of behaviors, however. Correlations between interobserver agreement and intraobserver consistency were variable but somewhat higher when interobserver agreement was the training criterion than when intraobserver consistency was the criterion. Correlations between interobserver agreement and criterion agreement ranged from — .16 to .89 during interobserver agreement training. Correlations between intraobserver consistency and criterion agreement ranged from — .23 to .99 during intraobserver consistency training.     

Comparative studies of squirrel monkeys (Saimiri sciureus) and titi monkeys (Callicebus moloch): performance on choice tasks in near space

Squirrel monkeys (Saimiri sciureus) and titi monkeys (Callicebus moloch) were studied in tasks involving reaching for food in near space (arm's reach). Although performance by monkeys of the two species differed in several ways familiar from previous studies, the species did not differ in the tendency to adopt a habitual position or limb during reaching. The findings contrast with previous work on spatial preferences in these species in tasks involving movement of the whole body. Together with the results of previous studies on movement patterns in these two species, the findings are placed in a comparative psychological framework of the proximate sources of use of space in nature.