Tower of London test: a comparison between conventional statistic approach and modelling based on artificial neural network in differentiating fronto-temporal dementia from Alzheimer's disease

The early differentiation of Alzheimer's disease (AD) from frontotemporal dementia (FTD) may be difficult. The Tower of London (ToL), thought to assess executive functions such as planning and visuo-spatial working memory, could help in this purpose. Twentytwo Dementia Centers consecutively recruited patients with early FTD or AD. ToL performances of these groups were analyzed using both the conventional statistical approaches and the Artificial Neural Networks (ANNs) modelling. Ninety-four non aphasic FTD and 160 AD patients were recruited. ToL Accuracy Score (AS) significantly (p < 0.05) differentiated FTD from AD patients. However, the discriminant validity of AS checked by ROC curve analysis, yielded no significant results in terms of sensitivity and specificity (AUC 0.63). The performances of the 12 Success Subscores (SS) together with age, gender and schooling years were entered into advanced ANNs developed by Semeion Institute. The best ANNs were selected and submitted to ROC curves. The non-linear model was able to discriminate FTD from AD with an average AUC for 7 independent trials of 0.82. The use of hidden information contained in the different items of ToL and the non linear processing of the data through ANNs allows a high discrimination between FTD and AD in individual patients.     

The subjective duration of audiovisual looming and receding stimuli

Looming visual stimuli (log-increasing in proximal size over time) and auditory stimuli (of increasing sound intensity over time) have been shown to be perceived as longer than receding visual and auditory stimuli (i.e., looming stimuli reversed in time). Here, we investigated whether such asymmetry in subjective duration also occurs for audiovisual looming and receding stimuli, as well as for stationary stimuli (i.e., stimuli that do not change in size and/or intensity over time). Our results showed a great temporal asymmetry in audition but a null asymmetry in vision. In contrast, the asymmetry in audiovision was moderate, suggesting that multisensory percepts arise from the integration of unimodal percepts in a maximum-likelihood fashion.     

The Interaction Between Culture, Health and Psychological Well-Being: Data Mining from the Italian Culture and Well-Being Project

The purpose of this study is to understand the impact of health status and cultural participation upon psychological well-being, with special attention to the interaction between patterns of cultural access and other factors known to affect psychological well-being. Data for this report were collected from a sample of 1,500 Italian citizens. A multi-step random sampling method was adopted to draw a large representative sample from the Italian population. Subjects underwent a standard questionnaire for psychological well-being [the Italian short form of the Psychological General Well Being Index (PGWBI)], and a questionnaire related to the frequency of participation to 15 different kinds of cultural activities during the previous year. The results show that, among the various potential factors considered, cultural access unexpectedly rankes as the second most important determinant of psychological well-being, immediately after the absence or presence of diseases, and outperforming factors such as job, age, income, civil status, education, place of living and other important factors. According to a semantic map generated by a powerful data mining algorithm, it turns out that different factors (among which cultural access and health status in particular) may be viewed as concurrent elements of a complex multi-causal scheme that seems to play a primary role in determining psychological distress or well-being. In particular, distress seems to be tightly connected with: living in the Southern part of Italy, average income level, living in semi-urban and urban areas, age group 46–60, presence of more than two concomitant diseases and a low level of cultural access. Well being, on the other hand, is tightly connected with: male gender, high cultural access, and absence of diseases. Some of these associations are confirmed by Principal Component Analysis.     

The Realist Wager: Challenging Rorty on His Home Ground

Philosophia - The paper is devoted to Richard Rorty’s thought, with the aim of exploiting a certain contention of his and directing it, as it were, against Rorty himself. Here is the...     

Communicating Science Effectively: When an Optimised Video Communication Enhances Comprehension,Pleasantness, and People’s Interest in Knowing More About Scientific Findings

In two experiments (N = 160) we predicted and found that an optimised video science communication was more effective than either a press release science communication (Experiment 1) and a non-optimised video science communication (Experiment 2) in promoting (a) a better comprehension of the communication, (b) a higher perceived pleasantness, and (c) a stronger manifest interest in learning more about its findings, as reflected in participants’ explicit requests to receive supplemental material on the communicated and analogous findings. The results were consistent across experiments. They were also not influenced by the content type of the communication. Implications for communication professionals and future research in the field of media, social influence, education, and applied social psychology are discussed.