The Effect of BRCA Gene Testing on Family Relationships: A Thematic Analysis of Qualitative Interviews

Discovery of mutations in the breast and ovarian cancer susceptibility genes BRCA1 and BRCA2 can have emotional consequences for both the tested individual and his or her relatives. This secondary analysis study investigated how BRCA testing impacts family dynamics and relationships. For the original study, a grounded theory inquiry, participants were recruited from a hereditary breast/ovarian cancer syndrome support website and open-ended interviews were performed asking about individual and family experiences after BRCA testing. All 12 participants whose interviews were included in the secondary analysis had a BRCA mutation. For the secondary analysis, thematic analysis was conducted and revealed three main themes characterizing the effect of BRCA testing on family relationships: 1. That the first in the family to have testing or seek genetic counseling takes on a special family role that can be difficult for them; 2. That discussions in the family often change; and 3. That individuals may feel more or less connected to certain family members. These changes seemed to relate to family cancer history, relationships, coping strategies, communication patterns, and mutation status. Genetic counselors might find it useful to explore these issues in order to prepare clients before BRCA testing and to support them through shifts in family dynamics after disclosure of results.     

Publication patterns in developmental psychology: Trends and social networks

Interest in publication patterns has been steady. Journals have instituted policies in an effort to curb bias and provide globally representative research. This study aimed to examine if publication patterns were present in two developmental psychology journals. It also explored the social networks of prominent authors and the prevalence of informal author–editor relationships, searching for any potential power groups. Data were taken from empirical articles published between 2005 and 2014 in Child Development (CD) and The International Journal of Early Childhood (IJEC) data points were geographical authorship affiliation, informal author relationships as established by co‐publishing, and connections to journal editors via identical affiliation. Results confirmed the previously established North American dominance in published research. In CD a strongly interlinked social network was identified between authors over the 10 years, with 15 chief influentialists binding groups of authors together. Results suggest that patterns are still present in published research in the realm of developmental psychology. To conclude, the potential implications of these patterns within developmental psychology are presented.     

Interaction between locale and taxon strategies in human spatial learning

Three computer-based experiments which tested human participants in a non-immersive virtual watermaze task sought to determine factors which dictate whether the presence of a visual platform disrupts locale learning and taxon learning. In Experiment 1, the visible platform disrupted locale but not taxon learning based on viewpoint-independent and viewpoint-dependent information, respectively. In Experiment 2, taxon learning based on non-geometric cues providing viewpoint-dependent information was disrupted by the visible platform when the cues required relational information to disambiguate them from other cues. Experiment 3 placed participants in an isosceles triangular pool. The presence of the visible platform did not disrupt the encoding of relational information provided by shape of the pool. These results support the notion that geometric cues are encoded in a separate module which is impenetrable to non-geometric cues not creating the shape of the environment.     

Ultradian rhythms of gastric acidity

Measurements of gastric pH and hydrogen ion concentration were made serially for six hours in five rhesus monkeys. Both pH and hydrogen ion concentration showed rapid fluctuations with periods approximating 90 minutes. These rhythms persisted in the face of continous infusion with Pentagastrin, indicating that while gastrin release is sufficient to stimulate acid secretion, it is not the only mechanism of acid control.