Reduction of caregiver burden in Alzheimer's disease by treatment with galantamine

Alzheimer's disease is a progressive condition characterized by a loss of cognition, altered behavior, and a loss of functional ability, such as bathing, dressing, toileting, and organizing finances. Family and friends provide nearly three quarters of all care for patients with Alzheimer's disease. This informal care results in significant burden to caregivers. Caregiver burden is the set of physical, psychological or emotional, social, and financial problems that family members may experience when caring for impaired older adults. Caregivers of Alzheimer's disease patients report higher rates of physical symptoms, mortality, depression, and fatigue, as well as adverse effects on employment compared with those who are not caregivers for Alzheimer's disease patients. In many cases, the same family members are responsible for both out-of-pocket expenditures and caregiving duties. For this article, a MEDLINE search using the key words "caregiver and Alzheimer's disease" and "cost and Alzheimer's disease" was performed. The purpose of this article is to review the literature on caregiver burden, the components of caregiver burden, effects of caregiving on the health of caregivers, the cost of Alzheimer's disease on the caregiver and society, and the benefits attainable with treatment.     

Neuropsychological Aspects of Pediatric Sickle Cell Disease

Sickle cell disease (SCD), a class of genetic disorders characterized by abnormal, sickled red blood cells, is a chronic illness that results in progressive cerebrovascular disease. Neurocognitive sequelae of clinically apparent cerebrovascular accidents in children with SCD are characterized by pervasive impairments, including decrements in general intellectual functioning, language and verbal abilities, visual-motor and visual-spatial processing, memory, academic achievement, and processing of subtle prosodic information. In contrast, subtle neurocognitive deficits in the areas of attention and concentration, executive function, and visual-motor speed and coordination appear to be associated with silent infarcts that are not necessarily detected on physical examination. Investigation of the disease course and associated neurocognitive sequelae suggest a disease-specific model of neuropsychological impairment. Recommendations are made for clinical and research efforts in the field of pediatric neuropsychology.     

The impact of competition on intrinsic motivation and creativity: considering gender, gender segregation and gender role orientation

The present research investigated whether competition influences children's artistic creativity and intrinsic motivation toward an art activity. Study 1 tested the hypothesis that boys' creativity would be enhanced by competition, while girls' creativity would be undermined. Fifty children (aged 6–10) made paper collages in one of two conditions; half competed for prizes and half did not. Results supported our hypotheses, and further showed that when children self-segregated by gender, the impact of competition was much more pronounced. Study 2 was designed to clarify the unexpected gender-segregation finding from Study 1. The Children's Sex Role Inventory [Boldizar, J.P. (1991). Assessing sex typing and androgyny in children: the Children's Sex Role Inventory. Developmental Psychology, 27, 505–515] was administered to 143 children (aged 6–11). One week later, these children made paper collages in one of four conditions; in addition to manipulating competition, assigned seating ensured that half of children were segregated by gender and half were not. Following the collage activity, an intrinsic and extrinsic motivation questionnaire was administered. Masculine children reported higher levels of intrinsic motivation when competing and when segregated by gender; they also reported higher levels of extrinsic motivation, especially when segregated by gender. These findings demonstrate that gender role is an important factor in determining children's responses to competition.     

Designer Theology: A Feminist Perspective

This is a critical look at the question of design from a feminist theological perspective. The author analyzes James Moore's 1995 Zygon article, "Cosmology and Theology: The Reemergence of Patriarchy." Then she looks at the relationship between science and religion from a feminist perspective, focusing on the kyriarchal nature of theology itself in light of the myriad power issues at hand. Finally, she suggests that, instead of pondering the notion of design, scientists and theologians might more fruitfully look for new ground for dialogue since feminist scholars are asking very different questions, not just answering questions differently.     

On the Construct Validity of Integrity Tests: Individual and Situational Factors as Predictors of Test Performance

Although integrity tests are widely applied in screening job applicants, there is a need for research for examining the construct validity of these tests. In the present study, a theoretical model examining the causes of destructive behavior in organizational settings was used to develop background data measures of individual and situational variables that might be related to integrity test scores. Subsequently, 692 undergraduates were asked to complete these background data scales along with (a) two overt integrity tests – the Reid Report and the Personnel Selection Inventory, and (b) two personality‐based measures – the delinquency and socialization scales of the California Psychological Inventory. When scores of these measures were correlated with and regressed on the background data scales, it was found that relevant individual variables, such as narcissism and power motives, and relevant situational variables, such as alienation and exposure to negative peer groups, were related to scores on both types of integrity tests. However, a stronger pattern of validity evidence was obtained for the personality‐based measures and, in all cases, situational variables were found to be better predictors than individual variables. The implications of these findings for the validity of inferences drawn from overt and personality‐based integrity tests are discussed.     

Women and Salary Negotiation: The Costs of Self-Advocacy

Introducing the concepts of self- and other-advocacy should prove useful as a means of understanding the different contexts in which women and men can effectively and comfortably exert power and influence when making requests. In this conceptual paper, social psychological research is reviewed demonstrating that women can advocate effectively on behalf of others without incurring costs, but gender-linked stereotypes, roles, and norms constrain them from advocating as freely and effectively for themselves. It is argued that women do not frequently make requests for themselves, because they have learned that they may ultimately lose more than they gain. This gendered difference has implications for ongoing pay and promotion inequities.     

Palm Beach County Child Abuse and Neglect System Redesign: Initial Process Evaluation

For the families in Palm Beach County who entered the child abuse and neglect system as a result of having a child placed into emergency shelter, their experience was that the system was frequently intimidating, confusing, and fragmented. The reaction of the children and their families to this system was often defensiveness and resistance. To increase the system's effectiveness, it was redesigned and privatized. The redesigned system included centralized shelter placement, a comprehensive assessment, independent service coordination, and treatment service provision within a managed care model. By emphasizing family involvement and quality service provision, the goal was to increase voluntary participation and improve family outcomes. Based on initial data, it appears that the redesigned system has been successfully implemented and has made notable progress toward meeting its system flow timeframes. The initial data also indicate that high percentages of families are participating in and are satisfied with the system, that children are spending less time in shelter placements, and that only one family has reentered the system.     

What’s Really at Issue with Novel Predictions?

In this paper I distinguish two kinds of predictivism, ‘timeless’ and ‘historicized’. The former is the conventional understanding of predictivism. However, I argue that its defense in the works of John Worrall (Scerri and Worrall 2001, Studies in History and Philosophy of Science 32, 407–452; Worrall 2002, In the Scope of Logic, Methodology and Philosophy of Science, 1, 191–209) and Patrick Maher (Maher 1988, PSA 1988, 1, pp. 273) is wanting. Alternatively, I promote an historicized predictivism, and briefly defend such a predictivism at the end of the paper.