Newborn Screening for Cystic Fibrosis: Parents’ Preferences Regarding Counseling At the Time of Infants’ Sweat Test

Newborn screening (NBS) protocols for cystic fibrosis (CF) are the first regional population-based programs to incorporate DNA analysis into their procedures. Research about these programs can inform policy and practice regarding how best to counsel families with abnormal NBS results. The grounded theory method guided interviews with 33 families whose infants had abnormal CF NBS results. A dimensional analysis of these interviews provided a theoretical framework describing parents’ preferences regarding counseling during their infant's sweat test appointment. This framework describes the contexts and characteristics of the two main dimensions of parents’ preferences: factual information and emotional support. Factual information included learning about the probability of a CF diagnosis, CF disease facts, sweat test procedure, and CF genetics. Social support consisted of offering parents a choice about the timing and amount of CF information, showing empathy for their distress, instilling hope, personalizing counseling, and providing hospitality. This framework also explains the consequences of counseling that matched versus mismatched parental preferences in these domains. Counseling that matched parents preferences reduced parents’ distress while mismatched counseling tended to increase parents’ worry about their infant.     

Integrating ethics in design through the value-sensitive design approach

The Accreditation Board of Engineering and Technology (ABET) has declared that to achieve accredited status, “engineering programs must demonstrate that their graduates have an understanding of professional and ethical responsibility.” Many engineering professors struggle to integrate this required ethics instruction in technical classes and projects because of the lack of a formalized ethics-in-design approach. However, one methodology developed in human-computer interaction research, the Value-Sensitive Design approach, can serve as an engineering education tool which bridges the gap between design and ethics for many engineering disciplines. The three major components of Value-Sensitive Design, conceptual, technical, and empirical, exemplified through a case study which focuses on the development of a command and control supervisory interface for a military cruise missile.     

Discrimination and exiting homelessness among homeless adolescents

This article examines how newly homeless adolescents' discrimination experiences were associated with exiting homelessness after 6 months. A sample of 262 homeless adolescents, aged 12 to 20 years, were recruited and followed longitudinally (6-month retention rate = 88%). Discrimination was related to being gay, lesbian, or bisexual (LGB). Discrimination from family was related to exiting homelessness. Other than those who were LGB, adolescents who reported discrimination from their families were more likely to exit homelessness than adolescents who did not report such discrimination. Suggestions for future research include focusing on the experiences of LGB homeless adolescents, the role of families in the lives of homeless adolescents, and other aspects of discrimination, including salience, frequency, intensity, and duration.     

Animal models of drug addiction: Where do we go from here?

Compulsion and impulsivity are both primary features of drug addiction. Based on decades of animal research, we have a detailed understanding of the factors (both environmental and physiological) that influence compulsive drug use, but still know relatively little about the impulsive aspects of drug addiction. This review outlines our current knowledge of the relationship between impulsivity and drug addiction, focusing on cognitive and motor impulsivity, which are particularly relevant to this disorder. Topics to be discussed include the influence of chronic drug administration on impulsivity, the mechanisms that may explain drug-induced impulsivity, and the role of individual differences in the development of impulsive drug use. In addition, the manner in which contemporary theories of drug addiction conceptualize the relationship between impulsivity and compulsion is examined. Most importantly, this review emphasizes a critical role for animal research in understanding the role of impulsivity in the development and maintenance of drug addiction.     

Traits and stories: links between dispositional and narrative features of personality

Dispositional traits and life narratives represent two different levels of personality that have not previously been empirically linked. The current study tested five hypotheses connecting Big-Five traits to life-narrative indices of emotional tone, theme, and structure. Students (Study 1) and adults (Study 2) completed a self-report measure of the Big-Five traits and provided extended written accounts of either ten (students) or eight (adults) key life-narrative scenes, including life high points, low points, and turning points. Content analysis of the narrative data revealed that for both samples Neuroticism was positively associated with an emotionally negative life-narrative tone, Agreeableness was correlated with narrative themes of communion (e.g., friendship, caring for others), and Openness was strongly associated with the structural complexity of life narrative accounts. Contrary to prediction, however, Conscientiousness was not consistently associated with themes of agency (e.g., achievement, self-mastery) and Extraversion was unrelated to positive narrative tone. The results are discussed in the context of contemporary research and theorizing on the narrative study of lives and the relation of narrative research in personality to more conventional, trait-based approaches.     

Construct validity of the relationship profile test: impact of gender, gender role, and gender role stereotype

Research supports the construct validity of the Relationship Profile Test (RPT; Bornstein & Languirand, 2003), a 30-item, self-report measure of destructive overdependence (DO), dysfunctional detachment (DD), and healthy dependency. In this investigation, we assessed the relationships of gender, gender role, and gender role stereotype ratings to RPT subscale scores. In Study 1, we replicated earlier patterns of gender differences in RPT scores, assessed cross-sample consistency in gender difference effect sizes, and provided preliminary nonclinical norms for the RPT subscales. Study 2 showed that--as expected--DO items are perceived as stereotypically feminine, whereas DD items are perceived as stereotypically masculine. In Study 3, we examined the relationships of RPT subscale scores to masculinity, femininity, and androgyny scores. We discuss the theoretical, empirical, and clinical implications of these findings.     

Self-reported comfort in athletic training to same- and opposite-sex athletes

To assess the comfort of athletic trainers in providing care to athletes of the same- and opposite-sex, the Gender Comfort in Athletic Training Questionnaire was developed. Cronbach alpha was .72. The 8-item questionnaire was mailed to 235 participants, who were senior athletic training students and clinical instructors affiliated with 14 university athletic training programs. 192 questionnaires were returned (82%). Only one t test showed a significant mean difference in reported comfort between women (n= 103, M=2.8, SD= 0.8; disagree) and men (n= 89, M=3.1, SD=0.8; neutral) on the statement: I feel more comfortable providing athletic training services to male athletes than female athletes. The women and men in this sample were similar in their self-ratings of comfort in providing athletic training services to male and female athletes.     

The neurophysiological correlates of face processing in adults and children with Asperger's syndrome

Past research has found evidence for face and emotional expression processing differences between individuals with Asperger's syndrome (AS) and neurotypical (NT) controls at both the neurological and behavioural levels. The aim of the present study was to examine the neurophysiological basis of emotional expression processing in children and adults with AS relative to age- and gender-matched NT controls. High-density event-related potentials were recorded during explicit processing of happy, sad, angry, scared, and neutral faces. Adults with AS were found to exhibit delayed P1 and N170 latencies and smaller N170 amplitudes in comparison to control subjects for all expressions. This may reflect impaired holistic and configural processing of faces in AS adults. However, these differences were not observed between AS and control children. This may result from incomplete development of the neuronal generators of these ERP components and/or early intervention.     

Life stress, the "kindling" hypothesis, and the recurrence of depression: considerations from a life stress perspective

Major depression is frequently characterized by recurrent episodes over the life course. First lifetime episodes of depression, however, are typically more strongly associated with major life stress than are successive recurrences. A key theoretical issue involves how the role of major life stress changes from an initial episode over subsequent recurrences. The primary conceptual framework for research on life stress and recurrence of depression is the "kindling" hypothesis (R. M. Post, 1992). Despite the strengths of the kindling hypothesis, a review of the research literature reveals inconsistencies and confusion about life stress and its implications for the recurrence of depression. Adopting a life stress perspective, the authors introduce 3 major themes that resolve the inconsistencies in the current literature. They integrate these themes and extrapolate the ideas with available data to develop a preliminary framework for evaluating competing explanatory models and to guide research on life stress and the recurrence of depression.