The effects of reversible lidocaine-induced lesion of the tissue surrounding the anterior ventral wall of the third ventricle on drinking in rats.

The local anesthetic lidocaine (XILOCAINA), 2%, was injected into the tissue surrounding the anterior region of the third cerebral ventricle (AV3V) of the rat, through a permanently implanted cannula, to produce a temporary and reversible disruption of the nervous connections of this area with other cellular nuclei while leaving the vascular connections intact. Following 24 h water deprivation, lidocaine was injected, and after 20 min water intake decreased; subsequently, the lidocaine-injected rats behaved similarly to control rats injected with artificial cerebrospinal fluid. Osmotic drinking was not affected. Prolonged adipsia or hyperdipsia did not occur. In nondeprived rats, lidocaine prevented angiotensin II-induced drinking. Following 24 h sodium depletion by peritoneal dialysis, lidocaine decreased the specific sodium appetite by 50% in animals with different levels of body sodium depletion. The data indicate that the integrity of the neural tissue of the AV3V is essential for a correct body water-salt regulation. Temporary "ablation" with lidocaine, which blocked neural activity but maintained the blood supply, produced responses different from most of those reported after electrolytic lesions. Therefore, lidocaine may be used as a tool to assess the response of this neural tissue to body fluid regulation.     

Wayfinding on foot from information in retinal, not optical, flow.

People find their way through cluttered environments with ease and without injury. How do they do it? Two approaches to wayfinding are considered: Differential motion parallax (DMP) is a retinal motion invariant of near and far objects moving against fixation; the information in optical flow (IOF) is a radial pattern of vectors, relying on decomposition of retinal flow. Evidence is presented that DMP guides wayfinding during natural gait, accounting for errors as well as correct responses. Evidence against IOF is also presented, and a space-time aliasing artifact that can contaminate IOF displays is explored. Finally, DMP and IOF are separated, showing they can yield different results in different environments. Thus, it is concluded that (a) DMP and IOF are different, (b) DMP and not IOF is used for wayfinding, (c) moving observers do not usually decompose retinal flow, and (d) optical flow may be a mathematical fiction with no psychological reality.     

Impairment of spontaneous alternation performance by an NMDA antagonist: attenuation with non-NMDA treatments.

N-Methyl-D-aspartate (NMDA) receptor antagonists disrupt learning on a variety of tasks. Previous findings indicate that glucose, naloxone, and physostigmine ameliorate learning deficits produced by several treatments. The present experiment examines whether these agents also reverse the amnestic effects of NMDA receptor blockade. Mice were tested for spontaneous alternation performance in a Y-maze. The animals received either saline or the NMDA antagonist, NPC 12626 (35 mg/kg, IP), 50 min prior to testing and received an additional injection of saline, glucose, naloxone, or physostigmine 30 min prior to testing. NPC 12626 significantly decreased alternation scores. Glucose (250 mg/kg), physostigmine (0.01 mg/kg), and naloxone (1 mg/kg) reversed the effects of NPC 12626. Thus, impairments of learning after NMDA receptor blockade share with other amnestic conditions the susceptibility to attenuation by glucose, naloxone, and physostigmine.     

Visual evoked potentials related to behavioral asymmetries during foveal attention in the two extrapersonal Hemispaces

In a group of male and female subjects we studied the VEPs related to the solution of a lexical decision task presented in the Left and Right Hemispaces with respect to the Central position in order to explore the electrophysiological correlates of the performance asymmetries obtained when overt spatial attention is directed to the Left or Right Hemispace. When stimuli were presented in the Left Hemispace a significant asymmetry was observed between the two hemispheres of the negative activity around 280 msec in the occipital-parietal areas. Moreover a general increase in the Central and Frontal areas of both the hemispheres was observed. In this paper we discuss why these effects can be considered to be the cause of the costs on accuracy observed in the male subjects. The differences obtained with the female group are discussed in relation to the observed modification on the negative activity around 400 msec with stimuli in the Left Hemispace. These findings give some suggestions about the interaction of structural and attentional mechanisms in the brain during the solution of a lateralized cognitive task.     

Patterns of coping with cancer.

We identified five patterns of coping in a sample of 603 cancer patients: "seeking or using social support," "focusing on the positive," "distancing," "cognitive escape-avoidance," and "behavioral escape-avoidance." Relationships of these coping patterns to sociodemographic characteristics, medical factors, stress appraisals, psychotherapeutic experience, and emotional distress were tested using correlational and regression techniques. Type of cancer, time since diagnosis, and whether a person was currently in treatment had few or no relationships to coping. The specific cancer-related problem (e.g., pain, fear of future) was also not associated with how individuals coped. Perceptions of its stressfulness, however, were related to significantly more coping through social support and more of both forms of escape-avoidance. Coping through social support, focusing on the positive, and distancing was associated with less emotional distress, whereas using cognitive and behavioral escape-avoidance was associated with more emotional distress. Implications of the results for understanding coping processes and intervention with cancer patients are discussed.     

The Personal and Social Worries of Adolescents in Northern Ireland: Results of a Survey

The aim of this study was to ascertain the self-perceived social and personal concerns of adolescents attending educational institutions in Northern Ireland. 446 questionnaires from 15-18-year-old students at ten institutions were analysed in order to determine the frequency with which respondents reported worrying about the following broad areas: school, choosing a job, finding a job, home, starting work, opposite-sex relationships, personal issues, and relating to others. The effects of variables such as gender, age and nature of educational institution attended were also examined. The results indicated that most frequent worry was reported about finding and choosing employment, personal issues and opposite-sex relationships. Gender, age and religious affiliation of school attended exerted major effects. Implications for those involved in working with adolescents within educational contexts are discussed.     

By your attributions you shall be known: Consequences of attributional accounts for professional and gender identities

We demonstrate the power of a situated identity perspective for understanding the different attributional patterns of women and men in an academic setting and their differential experiences in the workplace. Two explanations for the gender difference found in attributions of success are considered. This difference may be due either to different identities being attributed to men and women employing the same explanations for success and failure, or to the inconsistency between actions that confirm a professional (academic) identity and women's gender identity. The results of this survey of senior social science faculty men support the latter explanation but not the former. An editorial acceptance was seen as more professional but less feminine than a rejection. In the eyes of senior colleagues, the modest account of success, typical of women academics, enhances femininity but detracts from professionalism. The self-serving account typical of men makes the offerer appear less feminine but more professional. Thus in their situated identity claims, successful academic women, but not men, must choose between their professional and gender identities. Despite the movement of women into university social science positions, the role of academic has a masculine face.Order of authors was determined by a coin toss.     

A typology of personal and environmental sexual harassment: Research and policy implications for the 1990s

Most of the research conducted on sexual harassment over the last decade and a half has used categories that are neither mutually exclusive nor exhaustive. This has created problems for researchers: it is difficult to compare results from one study to another, harassment types that have scholarly and legal-policy relevance are omitted, and the ability of researchers to inform legal and policy decisions is diminished as a result of these problems. A comprehensive categorization of harassment types that addresses these methodological problems is presented. Specifically, 11 specific types of harassment—4 types of Verbal Requests, 3 Verbal Remarks, and 4 Nonverbal Displays—are presented with examples from research and legal literatures. Recommendations for reconceptualizing research definitions of harassment as well as for diversifying the methodological approaches to the topic are made.     

An exploratory study of videotapes of long-term group psychotherapy of outpatients with major and chronic mental illness

This study explored patterns emerging in videotaped sessions of group psychotherapy with seven outpatients of a large mental health facility. The 22 sessions spanned the 12th to 27th months of the group's existence. Group members had long histories (25–50 years) of symptoms characteristic of schizophrenia. Each session was rated on the Group Environment Scale. One session from a group in its earlier stages was also rated on the same instrument to give some indication of baseline patterns. Analyses of changes across the 15 months were not statistically significant. However, some GES subscales, including Cohesion, Independence, and Self-Discovery, showed relatively high mean levels across the 15-month period. These elevations are discussed as suggesting the codevelopment of orientations that have sometimes been viewed as incompatible and unattainable for schizophrenics. Interpreted clinically, the GES patterns help to elaborate recent findings about the relatively good success of long-term group therapy with such populations. The study, although merely suggestive, illustrates the potential for gleaning solid and clinically useful data from group psychotherapy research.The authors would like to thank Drs. Jill Rierdan, Nina Fieldsteel, Joseph Christy, and an anonymous reviewer for their suggestions, Kendra Bryant for serving as the reliability rater, and Janet Eltinge for her skilled videotaping.