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261.
Genetic Cancer Risk Assessment and Counseling: Recommendations of the National Society of Genetic Counselors 总被引:4,自引:0,他引:4
Trepanier A Ahrens M McKinnon W Peters J Stopfer J Grumet SC Manley S Culver JO Acton R Larsen-Haidle J Correia LA Bennett R Pettersen B Ferlita TD Costalas JW Hunt K Donlon S Skrzynia C Farrell C Callif-Daley F Vockley CW;National Society of Genetic Counselors 《Journal of genetic counseling》2004,13(2):83-114
These cancer genetic counseling recommendations describe the medical, psychosocial, and ethical ramifications of identifying at-risk individuals through cancer risk assessment with or without genetic testing. They were developed by members of the Practice Issues Subcommittee of the National Society of Genetic Counselors Cancer Genetic Counseling Special Interest Group. The information contained in this document is derived from extensive review of the current literature on cancer genetic risk assessment and counseling as well as the personal expertise of genetic counselors specializing in cancer genetics. The recommendations are intended to provide information about the process of genetic counseling and risk assessment for hereditary cancer disorders rather than specific information about individual syndromes. Key components include the intake (medical and family histories), psychosocial assessment (assessment of risk perception), cancer risk assessment (determination and communication of risk), molecular testing for hereditary cancer syndromes (regulations, informed consent, and counseling process), and follow-up considerations. These recommendations should not be construed as dictating an exclusive course of management, nor does use of such recommendations guarantee a particular outcome. These recommendations do not displace a health care provider's professional judgment based on the clinical circumstances of a client. 相似文献
262.
263.
Nicholas Long Barbara-Jeanne Austin Mary M. Gound Abesie O. Kelly Adrienne A. Gardner Rick Dunn Stacy B. Harris Kim S. Miller 《Journal of child and family studies》2004,13(1):47-65
The Parents Matter! Program (PMP) has developed three interventions for parents of 4th and 5th grade African-American children (9–12 years old). The overarching goal of all three interventions is to provide parents with knowledge, skills, and support for enhancing their efforts to raise healthy children. The interventions are: (1) Enhanced Communication and Parenting (five 2
-hour sessions), (2) Brief Communication and Parenting (single 2
-hour session), and (3) General Health (single 2
-hour session). This article discusses the development of these interventions, presents an overview of the content of each intervention, and discusses issues related to the facilitation/presentation of these interventions. 相似文献
264.
Marshall MF 《Science and engineering ethics》2004,10(1):37-42
This paper gives an overview of the placebo effect in popular culture, especially as it pertains to the work of authors Patrick
O’Brian and Sinclair Lewis. The beloved physician as placebo, and the clinician scientist as villain are themes that respectively
inform the novels, The Hundred Days and Arrowsmith. Excerpts from the novels, and from film show how the placebo effect, and the randomized clinical trial, have emerged into
popular culture, and evolved over time.
An earlier version of this paper was presented at an international conference, “Placebo: Its Action and Place in Health Research
Today,” held in Warsaw, Poland on 12–13 April, 2003. 相似文献
265.
Adults with auditory-visual synesthesia agree that higher pitched sounds induce smaller, brighter visual percepts. We have
hypothesized that these correspondences are remnants of cross-modal neural connections that are present at birth and that
influence the development of perception and language even in adults and children without synesthesia. In this study, we explored
these correspondences in preschoolers (30-36 months; n=12 per experiment). The children were asked to indicate which of two
bouncing balls was making a centrally located sound. The balls varied in size and/or surface darkness; the sound varied in
pitch. The children reliably matched the higher pitched sound to a smaller and lighter (white) ball (Experiment 1), to a lighter
(white) ball (Experiment 2), and in one of two groups, to a smaller ball (Experiment 3). Children’s matching of pitch and
size cannot be attributed to intensity matching or to learning. These data support the hypothesis that some cross-modal correspondences
may be remnants of the neural mechanisms underlying neonatal perception. 相似文献
266.
267.
A structural analysis of working memory and related cognitive skills in young children 总被引:9,自引:0,他引:9
Alloway TP Gathercole SE Willis C Adams AM 《Journal of experimental child psychology》2004,87(2):85-106
The aim of this study was to investigate the functional organisation of working memory and related cognitive abilities in young children. A sample of 633 children aged between 4 and 6 years were tested on measures of verbal short-term memory, complex memory span, sentence repetition, phonological awareness, and nonverbal ability. The measurement model that provided the best fit of the data incorporates constructs that correspond to the central executive, phonological loop, and episodic buffer subcomponents of working memory, plus distinct but associated constructs associated with phonological awareness and nonverbal ability. 相似文献
268.
Strategy choices in simple and complex addition: Contributions of working memory and counting knowledge for children with mathematical disability 总被引:19,自引:0,他引:19
Geary DC Hoard MK Byrd-Craven J DeSoto MC 《Journal of experimental child psychology》2004,88(2):121-151
Groups of first-grade (mean age = 82 months), third-grade (mean age = 107 months), and fifth-grade (mean age = 131 months) children with a learning disability in mathematics (MD, n = 58) and their normally achieving peers (n = 91) were administered tasks that assessed their knowledge of counting principles, working memory, and the strategies used to solve simple (4+3) and complex (16+8) addition problems. In all grades, the children with MD showed a working memory deficit, and in first grade, the children with MD used less sophisticated strategies and committed more errors while solving simple and complex addition problems. The group differences in strategy usage and accuracy were related, in part, to the group difference in working memory and to group and individual differences in counting knowledge. Across grade-level and group, the switch from simple to complex addition problems resulted in a shift in the mix of problem-solving strategies. Individual differences in the strategy mix and in the strategy shift were related, in part, to individual differences in working memory capacity and counting knowledge. 相似文献
269.
Mondloch CJ Dobson KS Parsons J Maurer D 《Journal of experimental child psychology》2004,89(2):159-181
Children are nearly as sensitive as adults to some cues to facial identity (e.g., differences in the shape of internal features and the external contour), but children are much less sensitive to small differences in the spacing of facial features. To identify factors that contribute to this pattern, we compared 8-year-olds' sensitivity to spacing cues with that of adults under a variety of conditions. In the first two experiments, participants made same/different judgments about faces differing only in the spacing of facial features, with the variations being kept within natural limits. To measure the effect of attention, we reduced the salience of featural information by blurring faces and occluding features (Experiment 1). To measure the role of encoding speed and memory limitations, we presented pairs of faces simultaneously and for an unlimited time (Experiment 2). To determine whether participants' sensitivity would increase when spacing distortions were so extreme as to make the faces grotesque, we manipulated the spacing of features beyond normal limits and asked participants to rate each face on a "bizarreness" scale (Experiment 3). The results from the three experiments indicate that low salience, poor encoding efficiency, and limited memory can partially account for 8-year-olds' poor performance on face processing tasks that require sensitivity to the spacing of features, a kind of configural processing that underlies adults' expertise. However, even when the task is modified to compensate for these problems, children remain less sensitive than adults to the spacing of features. 相似文献
270.
Despite a growing awareness of the unique needs of psychiatric patients with co-occurring substance abuse and dependence disorders (i.e. dual diagnosis), there is a dearth of research investigating the prevalence of dual diagnosis in forensic psychiatric populations. Similarly, little work has been done to determine the implications of dual diagnosis for forensic psychiatric patients. Patients at the Thomas Embling Hospital in Victoria, Australia, were assessed to determine the prevalence of substance abuse disorders and mental illnesses within this population. Results reveal that the majority of patients (approximately 74%) have a lifetime substance abuse or dependence disorder. Information was collected concerning patients' criminal histories and the Level of Service Inventory, Revised, was completed for each patient who participated. Results suggest that patients with both major mental illnesses and substance abuse disorders have more extensive criminal histories and demonstrate a higher level of risks and needs when compared with patients with major mental illness alone. The implications for the development and delivery of effective forensic mental health services that address both co-occurring disorders are also discussed. 相似文献