The impact of HIV infection on society's perception of clinical trials

All international codes of research ethics and virtually all national legislation and regulation in the field of research involving human subjects project an attitude of protectionism. Written with the aim of avoiding a repetition of atrocities like those committed by the Nazi physician-researchers, calamities like the thalidomide experience, or ethical violations like those of the Tuskegee syphilis study, their dominant concerns are the protection of individuals from injury and from exploitation. In recent years, however, society's perception of clinical research has shifted dramatically. Now, largely as a consequence of the efforts of the AIDS activists, clinical research is widely perceived as benign and beneficial. Although this shift in attitude has resulted in some important improvements in research policies and practices, this new perception is just as wrong-headed as was the earlier excessive protectionism. It is necessary to maintain a balanced perspective; our policies should encourage the conduct of ethical research while maintaining the vigilance necessary to safeguard the rights and welfare of the subjects.     

Modifying law enforcement training simulators for use in basic research

Several approaches to using simulation as a method for teaching good judgment in the use of firearms by law enforcement officers and military personnel were investigated for their potential applications to research: the GAMMA Live Fire Video Training System, the FireArms Training Systems Simulator (FATS), and the Judgment Under Stress Training (JUST) simulator. Each instrument uses real-time, computer-controlled, life-sized projected video images of scenarios that may or may not present a threat, and handguns that fire real or simulated ammunition. The subjects respond to a sequence of “shoot/no-shoot” judgment scenarios resulting in data on judgment, reaction time, and accuracy. The JUST simulator was found to be more easily modifiable in capturing data on performance at microanalytic levels. Although true interactive simulations are not feasible with this system, this was not seen as a hindrance to its usefulness for research.     

Pantheism,theism and the problem of evil

International Journal for Philosophy of Religion -     

The Commercialization of Clinical Genetics: An Analysis of Interrelations Between Academic Centers and For-Profit Clinical Genetics Diagnostics Companies

The field of clinical genetics has undergone substantial commercialization, including the development of genetics diagnostics companies. Numerous for-profit corporations now offer genetic diagnostic services; until recently, these clinical services were provided almost exclusively through academic, not-for-profit medical centers. Some of these for-profit corporations have business and/or research relationships with academia. An evaluation of the interconnections between academia and the clinical genetics industry is an important first step in analyzing the risks and benefits of commercialization. We analyzed the personnel and business affiliations of 19 major U.S. for-profit clinical genetics diagnostics companies with universities, academic medical centers, and the scientific and medical genetics communities in a 2-year period, 1991–1992. We noted extensive connections between the for-profit sector and academia. At least 17% of high-ranking personnel and 85% of consultants for the companies had one or more academic ties. At least 68% of the companies had one or more business agreements with at least one university or academic medical center. These results raise many issues regarding the delivery of genetic medicine and the structure and function of academic medical genetics centers.     

Temporal binding errors are redistributed by the attentional blink

When one searches for a target among nontargets appearing in rapid serial visual presentation (RSVP), one’s errors in performance typically involve the misreporting of neighboring nontargets. Such illusory conjunctions or intrusion errors are distributed differently around the target, depending on task or stimulus variables. It is shown here that shifts in intrusion error patterns can be produced by the manipulation of attention alone. In a dual-task paradigm, the magnitude and distribution of intrusion errors changed systematically as a function of available attentional resources. Intrusion errors in RSVP tasks reflect internal capacity limitations for binding independent features. The present results support a two-stage model of RSVP target processing.     

Psychotherapists and the clergy: Fifty years later

Jung's two powerful articles on psychotherapy and the clergy, written in 1928 and 1932. are looked at from the vantage point of fifty years later and the author's experience in conducting analysis with many people from both vocations. He notes that relatively few people achieve the kind of integration of the ego that Jung writes about-an essentially religious experience-wherein the center of their existence now gravitates about the Self. Yet Jung's work and views have had a profound effect on spiritually inclined people of all ages. The predictions of Jung's articles, regarding therapy, the dissemination of pyschology to the masses, and other issues are examined.     

Development of calculation abilities in young children.

This study investigates the development of skills for solving verbally and nonverbally presented calculation problems in children between 4 and 6 years of age. Identical addition and subtraction calculations were presented in three problem-type formats: nonverbal problems, story problems, and number-fact problems. The nonverbal problems involved presenting sets of physical referents that were then transformed either by adding or removing elements. The child saw the initial set and the number of elements that were added or removed, but not the final set. The task was to construct an array that contained the number of elements in the final set. The story problems and number-fact problems were presented orally, without props. Results indicate that children as young as 4 years of age have some success on the nonverbal problems, showing that they can transform sets by adding or subtracting elements. In contrast, children do not achieve comparable levels of success on the story problems or number-fact problems until 5 1/2 to 6 1/2 years of age. Moreover, throughout the age range tested, children performed better on nonverbal problems than on either story problems or number-fact problems. These results suggest that children's earliest ability to add and subtract is based on experiences combining and separating sets of objects in the world and that this ability precedes the development of conventional verbal methods of calculating.     

Cognitive and projective measures of differentiation and their relationship to empathy

The present investigation compared cognitive and projective methods of assessing “differentiation,” Witkin's Embedded Figures Test (EFT) and Blatt's Concept of the Object Scale (COS), and reexamined expectations concerning the relationship between level of differentiation and capacity for empathy. Whether lesser or greater differentiation would promote empathy was of specific interest. Two forms of empathy were investigated, an “affective” form assessed by the Mehrabian Empathy Scale and a “cognitive” form assessed by the Hogan Empathy Scale. Expected sex differences in differentiation and empathy were also investigated. Results demonstrated consonance between COS and EFT measures of differentiation within the male sample only (p < .05). Individuals classified by EFT as relatively less differentiated (“field dependent”) produced more part object responses (p < .02) and those classified as more differentiated (“field independent”) showed a trend toward more whole object responses (p < .10) on the COS. Associations between measures of differentiation and empathy reached significance or showed trends in the male group only. Men with relatively lesser differentiation on the EFT (“field dependent”) showed greater “affective empathy” (p < .10) and men with greater differentiation on the COS showed greater “cognitive” empathy (p < .05). Women demonstrated higher levels of “affective” empathy than men (p < .001).     

Predictive validation of an insurance agent support person selection battery

This study investigated the predictive validity of a selection battery for insurance agent support persons. The selection battery included cognitive tests, personality scales, and biodata scales. Predictor data were collected as part of the agent support person selection process. Behavior summary scale ratings made by immediate supervisors of agent support persons were used as criteria in this study. Uncorrected correlations for six matched predictor composite-criterion dimension combinations identified in a previous concurrent validation study (Ashworth, Barge, Dunnette, & Carter, 1987) ranged from .17 (p<. 01) to .28 (p< .01) (M=.21, N=357).